TABLE IV.

12-Month Air Pollution Exposure and the Risk of CRS by Nasal Polyp Status in ADSMs

PollutantsModelCRS without nasal-polypsCRS with nasal polyps
n (case/control)ORs (95% CI)n (case/control)ORs (95% CI)
PM2.5Model 1308/3087.19 (2.54, 20.36)91/913.98 (0.88, 18.01)
Model 2308/3083.32 (0.63, 17.40)91/913.76 (0.35, 39.85)
PM10Model 1213/2130.97 (0.67, 1.40)66/661.10 (0.75, 1.62)
Model 2213/2130.97 (0.49, 1.91)66/667.34 (0.83, 65.00)
NO2Model 1132/1320.65 (0.36, 1.18)35/350.89 (0.37, 2.15)
Model 2132/1320.85 (0.27, 2.69)35/352.37 (0.15, 37.28)
OzoneModel 1258/2580.57 (0.34, 0.93)75/750.49 (0.24, 1.03)
Model 2258/2583.10 (0.93, 10.30)75/750.45 (0.11, 1.86)
PollutantsModelCRS without nasal-polypsCRS with nasal polyps
n (case/control)ORs (95% CI)n (case/control)ORs (95% CI)
PM2.5Model 1308/3087.19 (2.54, 20.36)91/913.98 (0.88, 18.01)
Model 2308/3083.32 (0.63, 17.40)91/913.76 (0.35, 39.85)
PM10Model 1213/2130.97 (0.67, 1.40)66/661.10 (0.75, 1.62)
Model 2213/2130.97 (0.49, 1.91)66/667.34 (0.83, 65.00)
NO2Model 1132/1320.65 (0.36, 1.18)35/350.89 (0.37, 2.15)
Model 2132/1320.85 (0.27, 2.69)35/352.37 (0.15, 37.28)
OzoneModel 1258/2580.57 (0.34, 0.93)75/750.49 (0.24, 1.03)
Model 2258/2583.10 (0.93, 10.30)75/750.45 (0.11, 1.86)

For PM2.5, PM10, and NO2, we used 5-µg/m3 unit increase; for ozone, we used each 1 IQR increase (0.005 units). Model 1 adjusted for age, gender, and diagnosis year. Model 2 further adjusted for smoking status. In the CRS without nasal-polyps group (n = 308), we have missing exposure data for PM10 (95 cases), NO2 (176 cases), and ozone (50 cases) in this study due to missing air pollution exposure from local EPA monitors. In the CRS with nasal-polyps group (n = 91), we have missing exposure data for PM10 (25 cases), NO2 (56 cases), and ozone (16 cases) in this study due to missing air pollution exposure from local EPA monitors.

TABLE IV.

12-Month Air Pollution Exposure and the Risk of CRS by Nasal Polyp Status in ADSMs

PollutantsModelCRS without nasal-polypsCRS with nasal polyps
n (case/control)ORs (95% CI)n (case/control)ORs (95% CI)
PM2.5Model 1308/3087.19 (2.54, 20.36)91/913.98 (0.88, 18.01)
Model 2308/3083.32 (0.63, 17.40)91/913.76 (0.35, 39.85)
PM10Model 1213/2130.97 (0.67, 1.40)66/661.10 (0.75, 1.62)
Model 2213/2130.97 (0.49, 1.91)66/667.34 (0.83, 65.00)
NO2Model 1132/1320.65 (0.36, 1.18)35/350.89 (0.37, 2.15)
Model 2132/1320.85 (0.27, 2.69)35/352.37 (0.15, 37.28)
OzoneModel 1258/2580.57 (0.34, 0.93)75/750.49 (0.24, 1.03)
Model 2258/2583.10 (0.93, 10.30)75/750.45 (0.11, 1.86)
PollutantsModelCRS without nasal-polypsCRS with nasal polyps
n (case/control)ORs (95% CI)n (case/control)ORs (95% CI)
PM2.5Model 1308/3087.19 (2.54, 20.36)91/913.98 (0.88, 18.01)
Model 2308/3083.32 (0.63, 17.40)91/913.76 (0.35, 39.85)
PM10Model 1213/2130.97 (0.67, 1.40)66/661.10 (0.75, 1.62)
Model 2213/2130.97 (0.49, 1.91)66/667.34 (0.83, 65.00)
NO2Model 1132/1320.65 (0.36, 1.18)35/350.89 (0.37, 2.15)
Model 2132/1320.85 (0.27, 2.69)35/352.37 (0.15, 37.28)
OzoneModel 1258/2580.57 (0.34, 0.93)75/750.49 (0.24, 1.03)
Model 2258/2583.10 (0.93, 10.30)75/750.45 (0.11, 1.86)

For PM2.5, PM10, and NO2, we used 5-µg/m3 unit increase; for ozone, we used each 1 IQR increase (0.005 units). Model 1 adjusted for age, gender, and diagnosis year. Model 2 further adjusted for smoking status. In the CRS without nasal-polyps group (n = 308), we have missing exposure data for PM10 (95 cases), NO2 (176 cases), and ozone (50 cases) in this study due to missing air pollution exposure from local EPA monitors. In the CRS with nasal-polyps group (n = 91), we have missing exposure data for PM10 (25 cases), NO2 (56 cases), and ozone (16 cases) in this study due to missing air pollution exposure from local EPA monitors.

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