The characteristics of the Index for Mortality Prediction After Cardiac Transplantation and the United Network for Organ Sharing risk scores and the risk stratification Scores
The IMPACT score . | The UNOS score . | The RSS . | |||
---|---|---|---|---|---|
Recipient variable . | Points . | Risk factors . | Points . | Risk factors . | Points . |
Age >60 years | 3 | Recipient factors | Recipient age: >70 years | 2.1 | |
Serum bilirubin, mg/dl | Age >65 years | 1 | Recipient age: 55–70 years | 1.2 | |
0–0.99 | 0 | Body mass index (kg/m2) | Previous cardiac surgery | 1.3 | |
1–1.99 | 1 | 30–35 | 1 | Aetiology: congenital | 2.3 |
2–3.99 | 3 | >35 | 2 | Aetiology: amyloidosis | 1.8 |
≥4 | 4 | MPAP >30 mmHg | 1 | Diabetes complicated by CVA | 1.4 |
Creatinine clearance, ml/min | Total bilirubin | eGFR <33 | 2.8 | ||
≥50 | 0 | 1.5–1.9 | 1 | eGFR 33–53 | 1.4 |
30–49 | 2 | >1.9 | 2 | Total bilirubin >2 | 1.7 |
<30 | 5 | Creatinine | Intubated | 1.8 | |
Dialysis between listing and transplant | 4 | 1.5–2.0 | 1 | Hospitalized | 1.2 |
Female sex | 3 | >2.0 | 2 | RVAD-only | 4.7 |
Heart failure aetiology | Previous transplant | 2 | ECMO | 3.9 | |
Idiopathic | 0 | Previous cancer | 2 | Extracorporeal LVAD | 2.7 |
Ischaemic | 2 | Ventilator | 2 | Total artificial heart | 2.4 |
Congenital | 5 | Mechanical circulatory support | Paracorporeal LVAD | 2.7 | |
Others | 1 | Noncontinuous-flow ventricular assist device | 2 | Hepatitis C (+) donor | 2.1 |
Recent infection | 3 | Donor age: 50–55 years | 1 | Insulin-dependent donor | 1.8 |
Intra-aortic balloon pump | 3 | Donor age: >55 years | 2 | Donor age: 50–59 years | 1.7 |
Mechanical ventilation pretransplant | 5 | Ischaemia time >4 h | 2 | Donor age: 40–49 years | 1.5 |
Race | Gender mismatch | 1 | Donor age: 30–39 years | 1.3 | |
White | 0 | Diabetes | 1 | Ischaemic time >6 h | 1.7 |
African American | 3 | Total points | 22 | Ischaemic time 4–6 h | 1.4 |
Hispanic | 0 | Female donor: male recipient | 1.2 | ||
Others | 0 | Female donor: female recipient | 1.2 | ||
Temporary circulatory supporta | 7 | Total points | 49.3 | ||
Ventricular assist device | |||||
Older-generation pulsatile | 3 | ||||
Newer-generation continuousb | 5 | ||||
HeartMate II | 0 | ||||
Total points | 50 |
The IMPACT score . | The UNOS score . | The RSS . | |||
---|---|---|---|---|---|
Recipient variable . | Points . | Risk factors . | Points . | Risk factors . | Points . |
Age >60 years | 3 | Recipient factors | Recipient age: >70 years | 2.1 | |
Serum bilirubin, mg/dl | Age >65 years | 1 | Recipient age: 55–70 years | 1.2 | |
0–0.99 | 0 | Body mass index (kg/m2) | Previous cardiac surgery | 1.3 | |
1–1.99 | 1 | 30–35 | 1 | Aetiology: congenital | 2.3 |
2–3.99 | 3 | >35 | 2 | Aetiology: amyloidosis | 1.8 |
≥4 | 4 | MPAP >30 mmHg | 1 | Diabetes complicated by CVA | 1.4 |
Creatinine clearance, ml/min | Total bilirubin | eGFR <33 | 2.8 | ||
≥50 | 0 | 1.5–1.9 | 1 | eGFR 33–53 | 1.4 |
30–49 | 2 | >1.9 | 2 | Total bilirubin >2 | 1.7 |
<30 | 5 | Creatinine | Intubated | 1.8 | |
Dialysis between listing and transplant | 4 | 1.5–2.0 | 1 | Hospitalized | 1.2 |
Female sex | 3 | >2.0 | 2 | RVAD-only | 4.7 |
Heart failure aetiology | Previous transplant | 2 | ECMO | 3.9 | |
Idiopathic | 0 | Previous cancer | 2 | Extracorporeal LVAD | 2.7 |
Ischaemic | 2 | Ventilator | 2 | Total artificial heart | 2.4 |
Congenital | 5 | Mechanical circulatory support | Paracorporeal LVAD | 2.7 | |
Others | 1 | Noncontinuous-flow ventricular assist device | 2 | Hepatitis C (+) donor | 2.1 |
Recent infection | 3 | Donor age: 50–55 years | 1 | Insulin-dependent donor | 1.8 |
Intra-aortic balloon pump | 3 | Donor age: >55 years | 2 | Donor age: 50–59 years | 1.7 |
Mechanical ventilation pretransplant | 5 | Ischaemia time >4 h | 2 | Donor age: 40–49 years | 1.5 |
Race | Gender mismatch | 1 | Donor age: 30–39 years | 1.3 | |
White | 0 | Diabetes | 1 | Ischaemic time >6 h | 1.7 |
African American | 3 | Total points | 22 | Ischaemic time 4–6 h | 1.4 |
Hispanic | 0 | Female donor: male recipient | 1.2 | ||
Others | 0 | Female donor: female recipient | 1.2 | ||
Temporary circulatory supporta | 7 | Total points | 49.3 | ||
Ventricular assist device | |||||
Older-generation pulsatile | 3 | ||||
Newer-generation continuousb | 5 | ||||
HeartMate II | 0 | ||||
Total points | 50 |
Temporary circulatory support includes extracorporeal membrane oxygenation and extracorporeal ventricular assist device support.
Excluding HeartMate II.
CVA: cerebrovascular accident; ECMO: extracorporeal membrane oxygenation; eGFR: estimated glomerular filtration rate; IMPACT: Index for Mortality Prediction After Cardiac Transplantation; LVAD: left ventricular assist device; MPAP: mean pulmonary artery pressure; RSS: risk stratification score; RVAD: right ventricular assist device; UNOS: United Network for Organ Sharing.
The characteristics of the Index for Mortality Prediction After Cardiac Transplantation and the United Network for Organ Sharing risk scores and the risk stratification Scores
The IMPACT score . | The UNOS score . | The RSS . | |||
---|---|---|---|---|---|
Recipient variable . | Points . | Risk factors . | Points . | Risk factors . | Points . |
Age >60 years | 3 | Recipient factors | Recipient age: >70 years | 2.1 | |
Serum bilirubin, mg/dl | Age >65 years | 1 | Recipient age: 55–70 years | 1.2 | |
0–0.99 | 0 | Body mass index (kg/m2) | Previous cardiac surgery | 1.3 | |
1–1.99 | 1 | 30–35 | 1 | Aetiology: congenital | 2.3 |
2–3.99 | 3 | >35 | 2 | Aetiology: amyloidosis | 1.8 |
≥4 | 4 | MPAP >30 mmHg | 1 | Diabetes complicated by CVA | 1.4 |
Creatinine clearance, ml/min | Total bilirubin | eGFR <33 | 2.8 | ||
≥50 | 0 | 1.5–1.9 | 1 | eGFR 33–53 | 1.4 |
30–49 | 2 | >1.9 | 2 | Total bilirubin >2 | 1.7 |
<30 | 5 | Creatinine | Intubated | 1.8 | |
Dialysis between listing and transplant | 4 | 1.5–2.0 | 1 | Hospitalized | 1.2 |
Female sex | 3 | >2.0 | 2 | RVAD-only | 4.7 |
Heart failure aetiology | Previous transplant | 2 | ECMO | 3.9 | |
Idiopathic | 0 | Previous cancer | 2 | Extracorporeal LVAD | 2.7 |
Ischaemic | 2 | Ventilator | 2 | Total artificial heart | 2.4 |
Congenital | 5 | Mechanical circulatory support | Paracorporeal LVAD | 2.7 | |
Others | 1 | Noncontinuous-flow ventricular assist device | 2 | Hepatitis C (+) donor | 2.1 |
Recent infection | 3 | Donor age: 50–55 years | 1 | Insulin-dependent donor | 1.8 |
Intra-aortic balloon pump | 3 | Donor age: >55 years | 2 | Donor age: 50–59 years | 1.7 |
Mechanical ventilation pretransplant | 5 | Ischaemia time >4 h | 2 | Donor age: 40–49 years | 1.5 |
Race | Gender mismatch | 1 | Donor age: 30–39 years | 1.3 | |
White | 0 | Diabetes | 1 | Ischaemic time >6 h | 1.7 |
African American | 3 | Total points | 22 | Ischaemic time 4–6 h | 1.4 |
Hispanic | 0 | Female donor: male recipient | 1.2 | ||
Others | 0 | Female donor: female recipient | 1.2 | ||
Temporary circulatory supporta | 7 | Total points | 49.3 | ||
Ventricular assist device | |||||
Older-generation pulsatile | 3 | ||||
Newer-generation continuousb | 5 | ||||
HeartMate II | 0 | ||||
Total points | 50 |
The IMPACT score . | The UNOS score . | The RSS . | |||
---|---|---|---|---|---|
Recipient variable . | Points . | Risk factors . | Points . | Risk factors . | Points . |
Age >60 years | 3 | Recipient factors | Recipient age: >70 years | 2.1 | |
Serum bilirubin, mg/dl | Age >65 years | 1 | Recipient age: 55–70 years | 1.2 | |
0–0.99 | 0 | Body mass index (kg/m2) | Previous cardiac surgery | 1.3 | |
1–1.99 | 1 | 30–35 | 1 | Aetiology: congenital | 2.3 |
2–3.99 | 3 | >35 | 2 | Aetiology: amyloidosis | 1.8 |
≥4 | 4 | MPAP >30 mmHg | 1 | Diabetes complicated by CVA | 1.4 |
Creatinine clearance, ml/min | Total bilirubin | eGFR <33 | 2.8 | ||
≥50 | 0 | 1.5–1.9 | 1 | eGFR 33–53 | 1.4 |
30–49 | 2 | >1.9 | 2 | Total bilirubin >2 | 1.7 |
<30 | 5 | Creatinine | Intubated | 1.8 | |
Dialysis between listing and transplant | 4 | 1.5–2.0 | 1 | Hospitalized | 1.2 |
Female sex | 3 | >2.0 | 2 | RVAD-only | 4.7 |
Heart failure aetiology | Previous transplant | 2 | ECMO | 3.9 | |
Idiopathic | 0 | Previous cancer | 2 | Extracorporeal LVAD | 2.7 |
Ischaemic | 2 | Ventilator | 2 | Total artificial heart | 2.4 |
Congenital | 5 | Mechanical circulatory support | Paracorporeal LVAD | 2.7 | |
Others | 1 | Noncontinuous-flow ventricular assist device | 2 | Hepatitis C (+) donor | 2.1 |
Recent infection | 3 | Donor age: 50–55 years | 1 | Insulin-dependent donor | 1.8 |
Intra-aortic balloon pump | 3 | Donor age: >55 years | 2 | Donor age: 50–59 years | 1.7 |
Mechanical ventilation pretransplant | 5 | Ischaemia time >4 h | 2 | Donor age: 40–49 years | 1.5 |
Race | Gender mismatch | 1 | Donor age: 30–39 years | 1.3 | |
White | 0 | Diabetes | 1 | Ischaemic time >6 h | 1.7 |
African American | 3 | Total points | 22 | Ischaemic time 4–6 h | 1.4 |
Hispanic | 0 | Female donor: male recipient | 1.2 | ||
Others | 0 | Female donor: female recipient | 1.2 | ||
Temporary circulatory supporta | 7 | Total points | 49.3 | ||
Ventricular assist device | |||||
Older-generation pulsatile | 3 | ||||
Newer-generation continuousb | 5 | ||||
HeartMate II | 0 | ||||
Total points | 50 |
Temporary circulatory support includes extracorporeal membrane oxygenation and extracorporeal ventricular assist device support.
Excluding HeartMate II.
CVA: cerebrovascular accident; ECMO: extracorporeal membrane oxygenation; eGFR: estimated glomerular filtration rate; IMPACT: Index for Mortality Prediction After Cardiac Transplantation; LVAD: left ventricular assist device; MPAP: mean pulmonary artery pressure; RSS: risk stratification score; RVAD: right ventricular assist device; UNOS: United Network for Organ Sharing.
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