Table 3. Open in new tab MICs (mg/L) of... | Oxford Academic

Table 3.

Open in new tab

MICs (mg/L) of aminoglycosides in N. gonorrhoeae reference strains WHO M³⁵ and WHO X³⁵ and corresponding transformants expressing elongation factor G R635L or M520I + R635L substitutions

	Etest (mg/L)
Isolate	Gentamicin	Kanamycin	Amikacin	Tobramycin	Streptomycin
WHO M	4	16	32	8	16
WHO M_R635L	16	128	256	32	128
WHO M_{M520I + R635L}	32	256	256	32	256
WHO X	4	16	32	4	16
WHO X_R635L	32	128	128	32	128
WHO X_{M520I + R635L}	32	>256	>256	32	>256

	Etest (mg/L)
Isolate	Gentamicin	Kanamycin	Amikacin	Tobramycin	Streptomycin
WHO M	4	16	32	8	16
WHO M_R635L	16	128	256	32	128
WHO M_{M520I + R635L}	32	256	256	32	256
WHO X	4	16	32	4	16
WHO X_R635L	32	128	128	32	128
WHO X_{M520I + R635L}	32	>256	>256	32	>256

Table 3.

Open in new tab

MICs (mg/L) of aminoglycosides in N. gonorrhoeae reference strains WHO M³⁵ and WHO X³⁵ and corresponding transformants expressing elongation factor G R635L or M520I + R635L substitutions

	Etest (mg/L)
Isolate	Gentamicin	Kanamycin	Amikacin	Tobramycin	Streptomycin
WHO M	4	16	32	8	16
WHO M_R635L	16	128	256	32	128
WHO M_{M520I + R635L}	32	256	256	32	256
WHO X	4	16	32	4	16
WHO X_R635L	32	128	128	32	128
WHO X_{M520I + R635L}	32	>256	>256	32	>256

	Etest (mg/L)
Isolate	Gentamicin	Kanamycin	Amikacin	Tobramycin	Streptomycin
WHO M	4	16	32	8	16
WHO M_R635L	16	128	256	32	128
WHO M_{M520I + R635L}	32	256	256	32	256
WHO X	4	16	32	4	16
WHO X_R635L	32	128	128	32	128
WHO X_{M520I + R635L}	32	>256	>256	32	>256