Table 3.

Predictors for SARS-CoV-2 neutralizing antibody decay >50% at 6-month after second vaccine dose

Clinical parametersUnivariate regression
Multivariate regression
POR95% CIPOR95% CI
JIA0.0117.3331.583–33.9670.01010.1301.757–58.415
SLE0.0600.1090.011–1.099
Prednisolone0.0600.1090.011–1.099
MTX0.0944.2860.781–23.525
HCQ0.0030.0680.011–0.410
Anti-TNF0.0247.0911.297–38.7650.01910.1421.469–70.005
Clinical parametersUnivariate regression
Multivariate regression
POR95% CIPOR95% CI
JIA0.0117.3331.583–33.9670.01010.1301.757–58.415
SLE0.0600.1090.011–1.099
Prednisolone0.0600.1090.011–1.099
MTX0.0944.2860.781–23.525
HCQ0.0030.0680.011–0.410
Anti-TNF0.0247.0911.297–38.7650.01910.1421.469–70.005

Confounders adjusted for include gender, race, age at first vaccination, diagnosis and medications. Variables that gave a P < 0.1 in the univariate logistic regression were entered into the multivariate logistic regression by a backward conditional method and confirmed with a forward conditional method. P-value <0.05 was considered statistically significant. Only variables with P-value <0.05 are shown above. SARS-CoV-2: severe acute respiratory syndrome coronavirus 2. OR: odds ratio.

Table 3.

Predictors for SARS-CoV-2 neutralizing antibody decay >50% at 6-month after second vaccine dose

Clinical parametersUnivariate regression
Multivariate regression
POR95% CIPOR95% CI
JIA0.0117.3331.583–33.9670.01010.1301.757–58.415
SLE0.0600.1090.011–1.099
Prednisolone0.0600.1090.011–1.099
MTX0.0944.2860.781–23.525
HCQ0.0030.0680.011–0.410
Anti-TNF0.0247.0911.297–38.7650.01910.1421.469–70.005
Clinical parametersUnivariate regression
Multivariate regression
POR95% CIPOR95% CI
JIA0.0117.3331.583–33.9670.01010.1301.757–58.415
SLE0.0600.1090.011–1.099
Prednisolone0.0600.1090.011–1.099
MTX0.0944.2860.781–23.525
HCQ0.0030.0680.011–0.410
Anti-TNF0.0247.0911.297–38.7650.01910.1421.469–70.005

Confounders adjusted for include gender, race, age at first vaccination, diagnosis and medications. Variables that gave a P < 0.1 in the univariate logistic regression were entered into the multivariate logistic regression by a backward conditional method and confirmed with a forward conditional method. P-value <0.05 was considered statistically significant. Only variables with P-value <0.05 are shown above. SARS-CoV-2: severe acute respiratory syndrome coronavirus 2. OR: odds ratio.

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