Predictors for SARS-CoV-2 neutralizing antibody decay >50% at 6-month after second vaccine dose
Clinical parameters . | Univariate regression . | Multivariate regression . | ||||
---|---|---|---|---|---|---|
P . | OR . | 95% CI . | P . | OR . | 95% CI . | |
JIA | 0.011 | 7.333 | 1.583–33.967 | 0.010 | 10.130 | 1.757–58.415 |
SLE | 0.060 | 0.109 | 0.011–1.099 | |||
Prednisolone | 0.060 | 0.109 | 0.011–1.099 | |||
MTX | 0.094 | 4.286 | 0.781–23.525 | |||
HCQ | 0.003 | 0.068 | 0.011–0.410 | |||
Anti-TNF | 0.024 | 7.091 | 1.297–38.765 | 0.019 | 10.142 | 1.469–70.005 |
Clinical parameters . | Univariate regression . | Multivariate regression . | ||||
---|---|---|---|---|---|---|
P . | OR . | 95% CI . | P . | OR . | 95% CI . | |
JIA | 0.011 | 7.333 | 1.583–33.967 | 0.010 | 10.130 | 1.757–58.415 |
SLE | 0.060 | 0.109 | 0.011–1.099 | |||
Prednisolone | 0.060 | 0.109 | 0.011–1.099 | |||
MTX | 0.094 | 4.286 | 0.781–23.525 | |||
HCQ | 0.003 | 0.068 | 0.011–0.410 | |||
Anti-TNF | 0.024 | 7.091 | 1.297–38.765 | 0.019 | 10.142 | 1.469–70.005 |
Confounders adjusted for include gender, race, age at first vaccination, diagnosis and medications. Variables that gave a P < 0.1 in the univariate logistic regression were entered into the multivariate logistic regression by a backward conditional method and confirmed with a forward conditional method. P-value <0.05 was considered statistically significant. Only variables with P-value <0.05 are shown above. SARS-CoV-2: severe acute respiratory syndrome coronavirus 2. OR: odds ratio.
Predictors for SARS-CoV-2 neutralizing antibody decay >50% at 6-month after second vaccine dose
Clinical parameters . | Univariate regression . | Multivariate regression . | ||||
---|---|---|---|---|---|---|
P . | OR . | 95% CI . | P . | OR . | 95% CI . | |
JIA | 0.011 | 7.333 | 1.583–33.967 | 0.010 | 10.130 | 1.757–58.415 |
SLE | 0.060 | 0.109 | 0.011–1.099 | |||
Prednisolone | 0.060 | 0.109 | 0.011–1.099 | |||
MTX | 0.094 | 4.286 | 0.781–23.525 | |||
HCQ | 0.003 | 0.068 | 0.011–0.410 | |||
Anti-TNF | 0.024 | 7.091 | 1.297–38.765 | 0.019 | 10.142 | 1.469–70.005 |
Clinical parameters . | Univariate regression . | Multivariate regression . | ||||
---|---|---|---|---|---|---|
P . | OR . | 95% CI . | P . | OR . | 95% CI . | |
JIA | 0.011 | 7.333 | 1.583–33.967 | 0.010 | 10.130 | 1.757–58.415 |
SLE | 0.060 | 0.109 | 0.011–1.099 | |||
Prednisolone | 0.060 | 0.109 | 0.011–1.099 | |||
MTX | 0.094 | 4.286 | 0.781–23.525 | |||
HCQ | 0.003 | 0.068 | 0.011–0.410 | |||
Anti-TNF | 0.024 | 7.091 | 1.297–38.765 | 0.019 | 10.142 | 1.469–70.005 |
Confounders adjusted for include gender, race, age at first vaccination, diagnosis and medications. Variables that gave a P < 0.1 in the univariate logistic regression were entered into the multivariate logistic regression by a backward conditional method and confirmed with a forward conditional method. P-value <0.05 was considered statistically significant. Only variables with P-value <0.05 are shown above. SARS-CoV-2: severe acute respiratory syndrome coronavirus 2. OR: odds ratio.
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