Table 2.

Treatment strategy used in EIA patients by 3 months

TotalRAPsAaxSpAUndifferentiated arthritisOther
N = 14 007N = 9729N = 1804N = 272N = 1661N = 541
No DMARD, n (%)2866 (21)1223 (13)452 (26)201 (80)689 (43)301 (60)
MTX, n (%)
 MTX monotherapy6008 (44)4591 (48)954 (56)13 (5)385 (24)65 (13)
 MTX combination1346 (10)1253 (13)25 (1)7 (3)54 (3)7 (1)
SSZ, n (%)
 SSZ monotherapy1280 (9)798 (8)224 (13)10 (4)202 (13)46 (9)
 SSZ combination244 (2)207 (2)15 (1)3 (1)17 (1)2 (0)
HCQ, n (%)
 HCQ monotherapy1813 (13)1450 (15)27 (2)8 (3)254 (16)74 (15)
 HCQ combination1352 (10)1282 (14)7 (0)4 (2)51 (3)8 (2)
Missing treatment information, n35123691215737
Corticosteroids, n (%)
 No4080 (30)2096 (22)882 (51)195 (79)632 (40)275 (55)
 Yes9513 (70)7417 (78)851 (49)51 (21)968 (60)226 (45)
Missing steroid information, n41421671266140
TotalRAPsAaxSpAUndifferentiated arthritisOther
N = 14 007N = 9729N = 1804N = 272N = 1661N = 541
No DMARD, n (%)2866 (21)1223 (13)452 (26)201 (80)689 (43)301 (60)
MTX, n (%)
 MTX monotherapy6008 (44)4591 (48)954 (56)13 (5)385 (24)65 (13)
 MTX combination1346 (10)1253 (13)25 (1)7 (3)54 (3)7 (1)
SSZ, n (%)
 SSZ monotherapy1280 (9)798 (8)224 (13)10 (4)202 (13)46 (9)
 SSZ combination244 (2)207 (2)15 (1)3 (1)17 (1)2 (0)
HCQ, n (%)
 HCQ monotherapy1813 (13)1450 (15)27 (2)8 (3)254 (16)74 (15)
 HCQ combination1352 (10)1282 (14)7 (0)4 (2)51 (3)8 (2)
Missing treatment information, n35123691215737
Corticosteroids, n (%)
 No4080 (30)2096 (22)882 (51)195 (79)632 (40)275 (55)
 Yes9513 (70)7417 (78)851 (49)51 (21)968 (60)226 (45)
Missing steroid information, n41421671266140

Early treatment strategy used in patients with EIA in England recruited to NEIAA. Individuals were considered at risk from February 2020 (date of first case of COVID-19 in NEIAA) or date of diagnosis (whichever was later) and censored at a COVID-19 event, May 2021 or death (whichever was sooner). EIA: early inflammatory arthritis; NEIAA: National Early Inflammatory Arthritis Audit; n: number of patients; COVID-19: coronavirus disease 2019.

Table 2.

Treatment strategy used in EIA patients by 3 months

TotalRAPsAaxSpAUndifferentiated arthritisOther
N = 14 007N = 9729N = 1804N = 272N = 1661N = 541
No DMARD, n (%)2866 (21)1223 (13)452 (26)201 (80)689 (43)301 (60)
MTX, n (%)
 MTX monotherapy6008 (44)4591 (48)954 (56)13 (5)385 (24)65 (13)
 MTX combination1346 (10)1253 (13)25 (1)7 (3)54 (3)7 (1)
SSZ, n (%)
 SSZ monotherapy1280 (9)798 (8)224 (13)10 (4)202 (13)46 (9)
 SSZ combination244 (2)207 (2)15 (1)3 (1)17 (1)2 (0)
HCQ, n (%)
 HCQ monotherapy1813 (13)1450 (15)27 (2)8 (3)254 (16)74 (15)
 HCQ combination1352 (10)1282 (14)7 (0)4 (2)51 (3)8 (2)
Missing treatment information, n35123691215737
Corticosteroids, n (%)
 No4080 (30)2096 (22)882 (51)195 (79)632 (40)275 (55)
 Yes9513 (70)7417 (78)851 (49)51 (21)968 (60)226 (45)
Missing steroid information, n41421671266140
TotalRAPsAaxSpAUndifferentiated arthritisOther
N = 14 007N = 9729N = 1804N = 272N = 1661N = 541
No DMARD, n (%)2866 (21)1223 (13)452 (26)201 (80)689 (43)301 (60)
MTX, n (%)
 MTX monotherapy6008 (44)4591 (48)954 (56)13 (5)385 (24)65 (13)
 MTX combination1346 (10)1253 (13)25 (1)7 (3)54 (3)7 (1)
SSZ, n (%)
 SSZ monotherapy1280 (9)798 (8)224 (13)10 (4)202 (13)46 (9)
 SSZ combination244 (2)207 (2)15 (1)3 (1)17 (1)2 (0)
HCQ, n (%)
 HCQ monotherapy1813 (13)1450 (15)27 (2)8 (3)254 (16)74 (15)
 HCQ combination1352 (10)1282 (14)7 (0)4 (2)51 (3)8 (2)
Missing treatment information, n35123691215737
Corticosteroids, n (%)
 No4080 (30)2096 (22)882 (51)195 (79)632 (40)275 (55)
 Yes9513 (70)7417 (78)851 (49)51 (21)968 (60)226 (45)
Missing steroid information, n41421671266140

Early treatment strategy used in patients with EIA in England recruited to NEIAA. Individuals were considered at risk from February 2020 (date of first case of COVID-19 in NEIAA) or date of diagnosis (whichever was later) and censored at a COVID-19 event, May 2021 or death (whichever was sooner). EIA: early inflammatory arthritis; NEIAA: National Early Inflammatory Arthritis Audit; n: number of patients; COVID-19: coronavirus disease 2019.

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