Table 1 Open in new tab Hazard ratio for...

Secondary outcome	Unadjusted	Adjusted
MI	1.41	(1.12–1.78)	0.004	1.40	(1.11–1.78)	0.005^a
Ischaemic stroke	1.19	(0.83–1.72)	0.336	1.13	(0.77–1.66)	0.536^b
Coronary revascularization	1.40	(1.13–1.72)	0.002	1.42	(1.14–1.75)	0.001^a
CHD death	1.40	(1.07–1.83)	0.013	1.52	(1.16–2.01)	0.003^c
CHD death and MI	1.31	(1.08–1.60)	0.007	1.35	(1.10–1.66)	0.004^a
CV death	1.27	(1.02–1.58)	0.029	1.39	(1.10–1.74)	0.005^a
CV death, MI, and ischaemic stroke	1.27	(1.07–1.51)	0.005	1.31	(1.09–1.56)	0.003^a
CV death, MI, ischaemic stroke, and coronary revascularization	1.26	(1.08–1.47)	0.003	1.29	(1.10–1.51)	0.002^a
All-cause mortality	1.04	(0.89–1.22)	0.622	1.10	(0.93–1.30)	0.255^a

Secondary outcome	Unadjusted	Adjusted
MI	1.41	(1.12–1.78)	0.004	1.40	(1.11–1.78)	0.005^a
Ischaemic stroke	1.19	(0.83–1.72)	0.336	1.13	(0.77–1.66)	0.536^b
Coronary revascularization	1.40	(1.13–1.72)	0.002	1.42	(1.14–1.75)	0.001^a
CHD death	1.40	(1.07–1.83)	0.013	1.52	(1.16–2.01)	0.003^c
CHD death and MI	1.31	(1.08–1.60)	0.007	1.35	(1.10–1.66)	0.004^a
CV death	1.27	(1.02–1.58)	0.029	1.39	(1.10–1.74)	0.005^a
CV death, MI, and ischaemic stroke	1.27	(1.07–1.51)	0.005	1.31	(1.09–1.56)	0.003^a
CV death, MI, ischaemic stroke, and coronary revascularization	1.26	(1.08–1.47)	0.003	1.29	(1.10–1.51)	0.002^a
All-cause mortality	1.04	(0.89–1.22)	0.622	1.10	(0.93–1.30)	0.255^a

Table 1

Hazard ratio for secondary cardiovascular outcomes associated with Lipoprotein(a) ≥ 200 vs. <200 nmol/L

Secondary outcome	Unadjusted			Adjusted
	HR	95% CI	P-value	HR	95% CI	P-value
MI	1.41	(1.12–1.78)	0.004	1.40	(1.11–1.78)	0.005^a
Ischaemic stroke	1.19	(0.83–1.72)	0.336	1.13	(0.77–1.66)	0.536^b
Coronary revascularization	1.40	(1.13–1.72)	0.002	1.42	(1.14–1.75)	0.001^a
CHD death	1.40	(1.07–1.83)	0.013	1.52	(1.16–2.01)	0.003^c
CHD death and MI	1.31	(1.08–1.60)	0.007	1.35	(1.10–1.66)	0.004^a
CV death	1.27	(1.02–1.58)	0.029	1.39	(1.10–1.74)	0.005^a
CV death, MI, and ischaemic stroke	1.27	(1.07–1.51)	0.005	1.31	(1.09–1.56)	0.003^a
CV death, MI, ischaemic stroke, and coronary revascularization	1.26	(1.08–1.47)	0.003	1.29	(1.10–1.51)	0.002^a
All-cause mortality	1.04	(0.89–1.22)	0.622	1.10	(0.93–1.30)	0.255^a

Secondary outcome	Unadjusted			Adjusted
	HR	95% CI	P-value	HR	95% CI	P-value
MI	1.41	(1.12–1.78)	0.004	1.40	(1.11–1.78)	0.005^a
Ischaemic stroke	1.19	(0.83–1.72)	0.336	1.13	(0.77–1.66)	0.536^b
Coronary revascularization	1.40	(1.13–1.72)	0.002	1.42	(1.14–1.75)	0.001^a
CHD death	1.40	(1.07–1.83)	0.013	1.52	(1.16–2.01)	0.003^c
CHD death and MI	1.31	(1.08–1.60)	0.007	1.35	(1.10–1.66)	0.004^a
CV death	1.27	(1.02–1.58)	0.029	1.39	(1.10–1.74)	0.005^a
CV death, MI, and ischaemic stroke	1.27	(1.07–1.51)	0.005	1.31	(1.09–1.56)	0.003^a
CV death, MI, ischaemic stroke, and coronary revascularization	1.26	(1.08–1.47)	0.003	1.29	(1.10–1.51)	0.002^a
All-cause mortality	1.04	(0.89–1.22)	0.622	1.10	(0.93–1.30)	0.255^a

Bold text indicates statistical significance at an alpha level of 0.05.

CI, confidence interval; CHD, coronary heart disease; CV, cardiovascular; HR, hazard ratio; MI, myocardial infarction.

Adjusted for: Age, sex, hypertension, hyperlipidaemia, diabetes mellitus, chronic kidney disease, and smoking.

Adjusted for: Age and sex.

Adjusted for: Age, sex, hypertension, hyperlipidaemia, diabetes mellitus, and chronic kidney disease.