Table 2.

Comparison of fetal–neonatal outcomes between pregnant women with and without SS

No. of events (%)
With SS (n = 449)Without SS (n = 2 099 694)Crude OR (95% CI)Adjusted OR (95% CI)a
Stillbirth9(2.00)16 229(0.77)2.54(1.20, 5.41)*2.14(1.01, 4.55)*
 Explained stillbirth0(0.00)1640(0.08)N/AN/A
 Unexplained stillbirth9(2.00)14 589(0.69)2.85(1.35, 6.03)*2.40(1.13, 5.09)*
Low birth weight (<2500 g)74(16.48)138 791(6.61)2.71(2.06, 3.55)*2.53(1.92, 3.33)*
Premature birth (<37 weeks)67(14.92)160 071(7.62)2.08(1.56, 2.79)*1.87(1.40, 2.51)*
Small for gestational age78(17.37)206 145(9.82)1.88(1.46, 2.42)*2.03(1.57, 2.63)*
Large for gestational age26(5.79)206 350(9.83)0.57(0.38, 0.86)*0.49(0.32, 0.74)*
1-min Apgar score (<7)27(6.01)40 364(1.92)3.27(2.13, 5.01)*2.95(1.92, 4.54)*
5-min Apgar score (<7)3(0.67)8274(0.39)1.73(0.56, 5.36)1.55(0.50, 4.78)
Fetal distress37(8.24)103 058(4.91)1.71(1.20, 2.44)*1.72(1.20, 2.45)*
Fetal abnormalities, any42(9.35)118 714(5.65)1.65(1.18, 2.30)*1.37(0.97, 1.92)
Central nervous system malformations8(0.87)9305(0.44)1.98(0.99, 3.95)1.87(0.93, 3.74)
Chromosomal abnormalities7(0.76)9696(0.46)1.74(0.83, 3.65)1.36(0.65, 2.87)
Decreased fetal movements15(1.63)50224(2.39)0.71(0.43, 1.17)0.64(0.39, 1.06)
Other/unspecified abnormalities31(3.36)45234(2.15)1.64(1.15, 2.33)*1.46(1.03, 2.09)*
No. of events (%)
With SS (n = 449)Without SS (n = 2 099 694)Crude OR (95% CI)Adjusted OR (95% CI)a
Stillbirth9(2.00)16 229(0.77)2.54(1.20, 5.41)*2.14(1.01, 4.55)*
 Explained stillbirth0(0.00)1640(0.08)N/AN/A
 Unexplained stillbirth9(2.00)14 589(0.69)2.85(1.35, 6.03)*2.40(1.13, 5.09)*
Low birth weight (<2500 g)74(16.48)138 791(6.61)2.71(2.06, 3.55)*2.53(1.92, 3.33)*
Premature birth (<37 weeks)67(14.92)160 071(7.62)2.08(1.56, 2.79)*1.87(1.40, 2.51)*
Small for gestational age78(17.37)206 145(9.82)1.88(1.46, 2.42)*2.03(1.57, 2.63)*
Large for gestational age26(5.79)206 350(9.83)0.57(0.38, 0.86)*0.49(0.32, 0.74)*
1-min Apgar score (<7)27(6.01)40 364(1.92)3.27(2.13, 5.01)*2.95(1.92, 4.54)*
5-min Apgar score (<7)3(0.67)8274(0.39)1.73(0.56, 5.36)1.55(0.50, 4.78)
Fetal distress37(8.24)103 058(4.91)1.71(1.20, 2.44)*1.72(1.20, 2.45)*
Fetal abnormalities, any42(9.35)118 714(5.65)1.65(1.18, 2.30)*1.37(0.97, 1.92)
Central nervous system malformations8(0.87)9305(0.44)1.98(0.99, 3.95)1.87(0.93, 3.74)
Chromosomal abnormalities7(0.76)9696(0.46)1.74(0.83, 3.65)1.36(0.65, 2.87)
Decreased fetal movements15(1.63)50224(2.39)0.71(0.43, 1.17)0.64(0.39, 1.06)
Other/unspecified abnormalities31(3.36)45234(2.15)1.64(1.15, 2.33)*1.46(1.03, 2.09)*
a

Adjusted for age, infant sex, Charlson comorbidity index, urbanization, income, occupation, birth year and maternal nationality.

OR, odds ratio; N/A, not applicable.

*

P < 0.05.

Table 2.

Comparison of fetal–neonatal outcomes between pregnant women with and without SS

No. of events (%)
With SS (n = 449)Without SS (n = 2 099 694)Crude OR (95% CI)Adjusted OR (95% CI)a
Stillbirth9(2.00)16 229(0.77)2.54(1.20, 5.41)*2.14(1.01, 4.55)*
 Explained stillbirth0(0.00)1640(0.08)N/AN/A
 Unexplained stillbirth9(2.00)14 589(0.69)2.85(1.35, 6.03)*2.40(1.13, 5.09)*
Low birth weight (<2500 g)74(16.48)138 791(6.61)2.71(2.06, 3.55)*2.53(1.92, 3.33)*
Premature birth (<37 weeks)67(14.92)160 071(7.62)2.08(1.56, 2.79)*1.87(1.40, 2.51)*
Small for gestational age78(17.37)206 145(9.82)1.88(1.46, 2.42)*2.03(1.57, 2.63)*
Large for gestational age26(5.79)206 350(9.83)0.57(0.38, 0.86)*0.49(0.32, 0.74)*
1-min Apgar score (<7)27(6.01)40 364(1.92)3.27(2.13, 5.01)*2.95(1.92, 4.54)*
5-min Apgar score (<7)3(0.67)8274(0.39)1.73(0.56, 5.36)1.55(0.50, 4.78)
Fetal distress37(8.24)103 058(4.91)1.71(1.20, 2.44)*1.72(1.20, 2.45)*
Fetal abnormalities, any42(9.35)118 714(5.65)1.65(1.18, 2.30)*1.37(0.97, 1.92)
Central nervous system malformations8(0.87)9305(0.44)1.98(0.99, 3.95)1.87(0.93, 3.74)
Chromosomal abnormalities7(0.76)9696(0.46)1.74(0.83, 3.65)1.36(0.65, 2.87)
Decreased fetal movements15(1.63)50224(2.39)0.71(0.43, 1.17)0.64(0.39, 1.06)
Other/unspecified abnormalities31(3.36)45234(2.15)1.64(1.15, 2.33)*1.46(1.03, 2.09)*
No. of events (%)
With SS (n = 449)Without SS (n = 2 099 694)Crude OR (95% CI)Adjusted OR (95% CI)a
Stillbirth9(2.00)16 229(0.77)2.54(1.20, 5.41)*2.14(1.01, 4.55)*
 Explained stillbirth0(0.00)1640(0.08)N/AN/A
 Unexplained stillbirth9(2.00)14 589(0.69)2.85(1.35, 6.03)*2.40(1.13, 5.09)*
Low birth weight (<2500 g)74(16.48)138 791(6.61)2.71(2.06, 3.55)*2.53(1.92, 3.33)*
Premature birth (<37 weeks)67(14.92)160 071(7.62)2.08(1.56, 2.79)*1.87(1.40, 2.51)*
Small for gestational age78(17.37)206 145(9.82)1.88(1.46, 2.42)*2.03(1.57, 2.63)*
Large for gestational age26(5.79)206 350(9.83)0.57(0.38, 0.86)*0.49(0.32, 0.74)*
1-min Apgar score (<7)27(6.01)40 364(1.92)3.27(2.13, 5.01)*2.95(1.92, 4.54)*
5-min Apgar score (<7)3(0.67)8274(0.39)1.73(0.56, 5.36)1.55(0.50, 4.78)
Fetal distress37(8.24)103 058(4.91)1.71(1.20, 2.44)*1.72(1.20, 2.45)*
Fetal abnormalities, any42(9.35)118 714(5.65)1.65(1.18, 2.30)*1.37(0.97, 1.92)
Central nervous system malformations8(0.87)9305(0.44)1.98(0.99, 3.95)1.87(0.93, 3.74)
Chromosomal abnormalities7(0.76)9696(0.46)1.74(0.83, 3.65)1.36(0.65, 2.87)
Decreased fetal movements15(1.63)50224(2.39)0.71(0.43, 1.17)0.64(0.39, 1.06)
Other/unspecified abnormalities31(3.36)45234(2.15)1.64(1.15, 2.33)*1.46(1.03, 2.09)*
a

Adjusted for age, infant sex, Charlson comorbidity index, urbanization, income, occupation, birth year and maternal nationality.

OR, odds ratio; N/A, not applicable.

*

P < 0.05.

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