Impact of postinduction PRO severity on achieving one year endoscopic remission (SES-CD <3) among participants with >5 mm ulcers at baseline endoscopy (n = 283).
| Postinduction PRO . | Unadjusted OR (95% CI) . | P Unadjusted . | Adjusted OR (95% CI) 1 . | P Adjusted . |
|---|---|---|---|---|
| Abdominal pain moderate/severe vs not | 1.43 (0.77-2.67) | 0.261 | 1.42 (0.76-2.66) | 0.272 |
| Stool frequency >3 vs ≤3 | 0.67 (0.33-1.33) | 0.251 | 0.58 (0.28-1.23) | 0.159 |
| General well-being (poor/very poor/terrible) vs not | 1.11 (0.59-2.07) | 0.752 | 1.10 (0.59-2.06) | 0.763 |
| Abdominal pain moderate/severe and stool frequency >3 vs not | 1.05 (0.49-2.27) | 0.896 | 1.02 (0.46-2.25) | 0.961 |
| Abdominal pain moderate/severe and general well-being (poor/very poor/terrible) vs not | 1.47 (0.78-2.77) | 0.238 | 1.46 (0.77-2.76) | 0.245 |
| Stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.72 (0.32-1.64) | 0.435 | 0.69 (0.30-1.59) | 0.380 |
| Abdominal pain moderate/severe, stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.95 (0.41-2.17) | 0.896 | 0.91 (0.39-2.14) | 0.836 |
| PRO3 remission (AP ≤1, SF ≤1.5 and GWB ≤1) | 0.97 (0.48-1.95) | 0.935 | 0.96 (0.48-1.93) | 0.907 |
| PRO2 remission (AP ≤1 and SF ≤1.5) | 0.91 (0.47-1.78) | 0.794 | 0.90 (0.46-1.76) | 0.760 |
| Postinduction PRO . | Unadjusted OR (95% CI) . | P Unadjusted . | Adjusted OR (95% CI) 1 . | P Adjusted . |
|---|---|---|---|---|
| Abdominal pain moderate/severe vs not | 1.43 (0.77-2.67) | 0.261 | 1.42 (0.76-2.66) | 0.272 |
| Stool frequency >3 vs ≤3 | 0.67 (0.33-1.33) | 0.251 | 0.58 (0.28-1.23) | 0.159 |
| General well-being (poor/very poor/terrible) vs not | 1.11 (0.59-2.07) | 0.752 | 1.10 (0.59-2.06) | 0.763 |
| Abdominal pain moderate/severe and stool frequency >3 vs not | 1.05 (0.49-2.27) | 0.896 | 1.02 (0.46-2.25) | 0.961 |
| Abdominal pain moderate/severe and general well-being (poor/very poor/terrible) vs not | 1.47 (0.78-2.77) | 0.238 | 1.46 (0.77-2.76) | 0.245 |
| Stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.72 (0.32-1.64) | 0.435 | 0.69 (0.30-1.59) | 0.380 |
| Abdominal pain moderate/severe, stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.95 (0.41-2.17) | 0.896 | 0.91 (0.39-2.14) | 0.836 |
| PRO3 remission (AP ≤1, SF ≤1.5 and GWB ≤1) | 0.97 (0.48-1.95) | 0.935 | 0.96 (0.48-1.93) | 0.907 |
| PRO2 remission (AP ≤1 and SF ≤1.5) | 0.91 (0.47-1.78) | 0.794 | 0.90 (0.46-1.76) | 0.760 |
1Adjusted for disease duration and treatment allocation.
Impact of postinduction PRO severity on achieving one year endoscopic remission (SES-CD <3) among participants with >5 mm ulcers at baseline endoscopy (n = 283).
| Postinduction PRO . | Unadjusted OR (95% CI) . | P Unadjusted . | Adjusted OR (95% CI) 1 . | P Adjusted . |
|---|---|---|---|---|
| Abdominal pain moderate/severe vs not | 1.43 (0.77-2.67) | 0.261 | 1.42 (0.76-2.66) | 0.272 |
| Stool frequency >3 vs ≤3 | 0.67 (0.33-1.33) | 0.251 | 0.58 (0.28-1.23) | 0.159 |
| General well-being (poor/very poor/terrible) vs not | 1.11 (0.59-2.07) | 0.752 | 1.10 (0.59-2.06) | 0.763 |
| Abdominal pain moderate/severe and stool frequency >3 vs not | 1.05 (0.49-2.27) | 0.896 | 1.02 (0.46-2.25) | 0.961 |
| Abdominal pain moderate/severe and general well-being (poor/very poor/terrible) vs not | 1.47 (0.78-2.77) | 0.238 | 1.46 (0.77-2.76) | 0.245 |
| Stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.72 (0.32-1.64) | 0.435 | 0.69 (0.30-1.59) | 0.380 |
| Abdominal pain moderate/severe, stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.95 (0.41-2.17) | 0.896 | 0.91 (0.39-2.14) | 0.836 |
| PRO3 remission (AP ≤1, SF ≤1.5 and GWB ≤1) | 0.97 (0.48-1.95) | 0.935 | 0.96 (0.48-1.93) | 0.907 |
| PRO2 remission (AP ≤1 and SF ≤1.5) | 0.91 (0.47-1.78) | 0.794 | 0.90 (0.46-1.76) | 0.760 |
| Postinduction PRO . | Unadjusted OR (95% CI) . | P Unadjusted . | Adjusted OR (95% CI) 1 . | P Adjusted . |
|---|---|---|---|---|
| Abdominal pain moderate/severe vs not | 1.43 (0.77-2.67) | 0.261 | 1.42 (0.76-2.66) | 0.272 |
| Stool frequency >3 vs ≤3 | 0.67 (0.33-1.33) | 0.251 | 0.58 (0.28-1.23) | 0.159 |
| General well-being (poor/very poor/terrible) vs not | 1.11 (0.59-2.07) | 0.752 | 1.10 (0.59-2.06) | 0.763 |
| Abdominal pain moderate/severe and stool frequency >3 vs not | 1.05 (0.49-2.27) | 0.896 | 1.02 (0.46-2.25) | 0.961 |
| Abdominal pain moderate/severe and general well-being (poor/very poor/terrible) vs not | 1.47 (0.78-2.77) | 0.238 | 1.46 (0.77-2.76) | 0.245 |
| Stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.72 (0.32-1.64) | 0.435 | 0.69 (0.30-1.59) | 0.380 |
| Abdominal pain moderate/severe, stool frequency >3 and general well-being (poor/very poor/terrible) vs not | 0.95 (0.41-2.17) | 0.896 | 0.91 (0.39-2.14) | 0.836 |
| PRO3 remission (AP ≤1, SF ≤1.5 and GWB ≤1) | 0.97 (0.48-1.95) | 0.935 | 0.96 (0.48-1.93) | 0.907 |
| PRO2 remission (AP ≤1 and SF ≤1.5) | 0.91 (0.47-1.78) | 0.794 | 0.90 (0.46-1.76) | 0.760 |
1Adjusted for disease duration and treatment allocation.
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