Table 3.
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Clinical and Genetic Prognostic Factors in TERTp Wild-Type GBM

Univariate AnalysisMultivariate Analysis
Prognostic factorHR (95% CI)P-valueHR (95% CI)P-value
Sex (male)2.00 (0.96–4.18).0652.12 (0.98–4.61).058
Age (>70 years)2.88 (1.38–6.00).005*2.69 (1.19–6.10).018*
KPS score (≤80 points)1.96 (0.92–4.18).0820.93 (0.40–2.16).862
Resection (90%>)2.24 (1.06–4.73).035*2.05 (0.92–4.58).079
PTEN loss and/or mut0.20 (0.08–0.46)<.001*0.29 (0.11–0.76).012*
Univariate AnalysisMultivariate Analysis
Prognostic factorHR (95% CI)P-valueHR (95% CI)P-value
Sex (male)2.00 (0.96–4.18).0652.12 (0.98–4.61).058
Age (>70 years)2.88 (1.38–6.00).005*2.69 (1.19–6.10).018*
KPS score (≤80 points)1.96 (0.92–4.18).0820.93 (0.40–2.16).862
Resection (90%>)2.24 (1.06–4.73).035*2.05 (0.92–4.58).079
PTEN loss and/or mut0.20 (0.08–0.46)<.001*0.29 (0.11–0.76).012*

KPS, Karnofsky Performance Status; mut, mutation.

*indicates statistical significance.

Table 3.
Open in new tab

Clinical and Genetic Prognostic Factors in TERTp Wild-Type GBM

Univariate AnalysisMultivariate Analysis
Prognostic factorHR (95% CI)P-valueHR (95% CI)P-value
Sex (male)2.00 (0.96–4.18).0652.12 (0.98–4.61).058
Age (>70 years)2.88 (1.38–6.00).005*2.69 (1.19–6.10).018*
KPS score (≤80 points)1.96 (0.92–4.18).0820.93 (0.40–2.16).862
Resection (90%>)2.24 (1.06–4.73).035*2.05 (0.92–4.58).079
PTEN loss and/or mut0.20 (0.08–0.46)<.001*0.29 (0.11–0.76).012*
Univariate AnalysisMultivariate Analysis
Prognostic factorHR (95% CI)P-valueHR (95% CI)P-value
Sex (male)2.00 (0.96–4.18).0652.12 (0.98–4.61).058
Age (>70 years)2.88 (1.38–6.00).005*2.69 (1.19–6.10).018*
KPS score (≤80 points)1.96 (0.92–4.18).0820.93 (0.40–2.16).862
Resection (90%>)2.24 (1.06–4.73).035*2.05 (0.92–4.58).079
PTEN loss and/or mut0.20 (0.08–0.46)<.001*0.29 (0.11–0.76).012*

KPS, Karnofsky Performance Status; mut, mutation.

*indicates statistical significance.

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