. | Study population (n = 77) . | CMR-RF ≤ 20% (n = 62) . | CMR-RF > 20% (n = 15) . | P value . |
---|---|---|---|---|
Demographics | ||||
Age, years | 80.4 ± 5.1 | 80.5 ± 5.0 | 80.4 ± 5.9 | 0.972 |
Male sex, n (%) | 36 (46.8) | 27 (43.5) | 9 (60) | 0.252 |
Body mass index (BMI), kg/m2 | 27.3 ± 4.0 | 27.1 ± 4.0 | 28.1 ± 4.1 | 0.402 |
Obesity, n (%) | 17 (22.1) | 12 (19.4) | 5 (33.3) | 0.300 |
Smoker, n (%) | 5 (6.5) | 3 (4.8) | 2 (13.3) | 0.249 |
Medical history | ||||
STS score | 2.38 ± 0.96 | 2.38 ± 0.93 | 2.35 ± 1.11 | 0.893 |
NYHA class | 2 [2–3] | 2 [2–3] | 2 [2–3] | 0.928 |
NYHA class III/IV, n (%) | 30 (39.0) | 24 (38.8) | 6 (40.0) | 0.927 |
Diabetes mellitus, n (%) | 20 (26.0) | 13 (21.0) | 7 (46.7) | 0.054 |
Coronary artery disease, n (%) | 41 (53.2) | 33 (53.2) | 8 (53.3) | 0.994 |
COPD, n (%) | 10 (13.0) | 8 (12.9) | 2 (13.3) | 1.000 |
Atrial fibrillation, n (%) | 17 (22.1) | 14 (22.6) | 3 (20.0) | 1.000 |
MDRD-GFR, mL/min | 64.8 ± 17.5 | 66.7 ± 17.0 | 57.0 ± 17.8 | 0.053 |
Haemoglobin level, mmol/L | 7.9 ± 0.9 | 8.0 ± 0.9 | 7.6 ± 1.0 | 0.122 |
Pre-procedural echocardiographic parameters | ||||
Aortic valve area, cm2 | 0.79 ± 0.18 | 0.78 ± 0.19 | 0.80 ± 0.11 | 0.794 |
Aortic valve mean gradient, mmHg | 45.2 ± 12.4 | 44.9 ± 11.6 | 46.5 ± 15.7 | 0.642 |
Aortic valve maximum velocity, m/s | 4.3 ± 0.6 | 4.3 ± 0.6 | 4.3 ± 0.6 | 0.583 |
Left ventricular ejection fraction, % | 54.2 ± 8.4 | 54.8 ± 8.3 | 51.7 ± 8.4 | 0.203 |
Moderate or severe aortic regurgitation, n (%) | 7 (9.1) | 6 (9.7) | 1 (6.7) | 1.000 |
. | Study population (n = 77) . | CMR-RF ≤ 20% (n = 62) . | CMR-RF > 20% (n = 15) . | P value . |
---|---|---|---|---|
Demographics | ||||
Age, years | 80.4 ± 5.1 | 80.5 ± 5.0 | 80.4 ± 5.9 | 0.972 |
Male sex, n (%) | 36 (46.8) | 27 (43.5) | 9 (60) | 0.252 |
Body mass index (BMI), kg/m2 | 27.3 ± 4.0 | 27.1 ± 4.0 | 28.1 ± 4.1 | 0.402 |
Obesity, n (%) | 17 (22.1) | 12 (19.4) | 5 (33.3) | 0.300 |
Smoker, n (%) | 5 (6.5) | 3 (4.8) | 2 (13.3) | 0.249 |
Medical history | ||||
STS score | 2.38 ± 0.96 | 2.38 ± 0.93 | 2.35 ± 1.11 | 0.893 |
NYHA class | 2 [2–3] | 2 [2–3] | 2 [2–3] | 0.928 |
NYHA class III/IV, n (%) | 30 (39.0) | 24 (38.8) | 6 (40.0) | 0.927 |
Diabetes mellitus, n (%) | 20 (26.0) | 13 (21.0) | 7 (46.7) | 0.054 |
Coronary artery disease, n (%) | 41 (53.2) | 33 (53.2) | 8 (53.3) | 0.994 |
COPD, n (%) | 10 (13.0) | 8 (12.9) | 2 (13.3) | 1.000 |
Atrial fibrillation, n (%) | 17 (22.1) | 14 (22.6) | 3 (20.0) | 1.000 |
MDRD-GFR, mL/min | 64.8 ± 17.5 | 66.7 ± 17.0 | 57.0 ± 17.8 | 0.053 |
Haemoglobin level, mmol/L | 7.9 ± 0.9 | 8.0 ± 0.9 | 7.6 ± 1.0 | 0.122 |
Pre-procedural echocardiographic parameters | ||||
Aortic valve area, cm2 | 0.79 ± 0.18 | 0.78 ± 0.19 | 0.80 ± 0.11 | 0.794 |
Aortic valve mean gradient, mmHg | 45.2 ± 12.4 | 44.9 ± 11.6 | 46.5 ± 15.7 | 0.642 |
Aortic valve maximum velocity, m/s | 4.3 ± 0.6 | 4.3 ± 0.6 | 4.3 ± 0.6 | 0.583 |
Left ventricular ejection fraction, % | 54.2 ± 8.4 | 54.8 ± 8.3 | 51.7 ± 8.4 | 0.203 |
Moderate or severe aortic regurgitation, n (%) | 7 (9.1) | 6 (9.7) | 1 (6.7) | 1.000 |
Data are presented as mean ± standard deviation, median [interquartile range], or as number (%).
CMR-RF, cardiac magnetic resonance-regurgitant fraction; COPD, chronic obstructive pulmonary disease; MDRD-GFR, Modification of Diet in Renal Disease—glomerular filtration rate; NYHA, New York Heart Association; STS, Society of Thoracic Surgeons.
. | Study population (n = 77) . | CMR-RF ≤ 20% (n = 62) . | CMR-RF > 20% (n = 15) . | P value . |
---|---|---|---|---|
Demographics | ||||
Age, years | 80.4 ± 5.1 | 80.5 ± 5.0 | 80.4 ± 5.9 | 0.972 |
Male sex, n (%) | 36 (46.8) | 27 (43.5) | 9 (60) | 0.252 |
Body mass index (BMI), kg/m2 | 27.3 ± 4.0 | 27.1 ± 4.0 | 28.1 ± 4.1 | 0.402 |
Obesity, n (%) | 17 (22.1) | 12 (19.4) | 5 (33.3) | 0.300 |
Smoker, n (%) | 5 (6.5) | 3 (4.8) | 2 (13.3) | 0.249 |
Medical history | ||||
STS score | 2.38 ± 0.96 | 2.38 ± 0.93 | 2.35 ± 1.11 | 0.893 |
NYHA class | 2 [2–3] | 2 [2–3] | 2 [2–3] | 0.928 |
NYHA class III/IV, n (%) | 30 (39.0) | 24 (38.8) | 6 (40.0) | 0.927 |
Diabetes mellitus, n (%) | 20 (26.0) | 13 (21.0) | 7 (46.7) | 0.054 |
Coronary artery disease, n (%) | 41 (53.2) | 33 (53.2) | 8 (53.3) | 0.994 |
COPD, n (%) | 10 (13.0) | 8 (12.9) | 2 (13.3) | 1.000 |
Atrial fibrillation, n (%) | 17 (22.1) | 14 (22.6) | 3 (20.0) | 1.000 |
MDRD-GFR, mL/min | 64.8 ± 17.5 | 66.7 ± 17.0 | 57.0 ± 17.8 | 0.053 |
Haemoglobin level, mmol/L | 7.9 ± 0.9 | 8.0 ± 0.9 | 7.6 ± 1.0 | 0.122 |
Pre-procedural echocardiographic parameters | ||||
Aortic valve area, cm2 | 0.79 ± 0.18 | 0.78 ± 0.19 | 0.80 ± 0.11 | 0.794 |
Aortic valve mean gradient, mmHg | 45.2 ± 12.4 | 44.9 ± 11.6 | 46.5 ± 15.7 | 0.642 |
Aortic valve maximum velocity, m/s | 4.3 ± 0.6 | 4.3 ± 0.6 | 4.3 ± 0.6 | 0.583 |
Left ventricular ejection fraction, % | 54.2 ± 8.4 | 54.8 ± 8.3 | 51.7 ± 8.4 | 0.203 |
Moderate or severe aortic regurgitation, n (%) | 7 (9.1) | 6 (9.7) | 1 (6.7) | 1.000 |
. | Study population (n = 77) . | CMR-RF ≤ 20% (n = 62) . | CMR-RF > 20% (n = 15) . | P value . |
---|---|---|---|---|
Demographics | ||||
Age, years | 80.4 ± 5.1 | 80.5 ± 5.0 | 80.4 ± 5.9 | 0.972 |
Male sex, n (%) | 36 (46.8) | 27 (43.5) | 9 (60) | 0.252 |
Body mass index (BMI), kg/m2 | 27.3 ± 4.0 | 27.1 ± 4.0 | 28.1 ± 4.1 | 0.402 |
Obesity, n (%) | 17 (22.1) | 12 (19.4) | 5 (33.3) | 0.300 |
Smoker, n (%) | 5 (6.5) | 3 (4.8) | 2 (13.3) | 0.249 |
Medical history | ||||
STS score | 2.38 ± 0.96 | 2.38 ± 0.93 | 2.35 ± 1.11 | 0.893 |
NYHA class | 2 [2–3] | 2 [2–3] | 2 [2–3] | 0.928 |
NYHA class III/IV, n (%) | 30 (39.0) | 24 (38.8) | 6 (40.0) | 0.927 |
Diabetes mellitus, n (%) | 20 (26.0) | 13 (21.0) | 7 (46.7) | 0.054 |
Coronary artery disease, n (%) | 41 (53.2) | 33 (53.2) | 8 (53.3) | 0.994 |
COPD, n (%) | 10 (13.0) | 8 (12.9) | 2 (13.3) | 1.000 |
Atrial fibrillation, n (%) | 17 (22.1) | 14 (22.6) | 3 (20.0) | 1.000 |
MDRD-GFR, mL/min | 64.8 ± 17.5 | 66.7 ± 17.0 | 57.0 ± 17.8 | 0.053 |
Haemoglobin level, mmol/L | 7.9 ± 0.9 | 8.0 ± 0.9 | 7.6 ± 1.0 | 0.122 |
Pre-procedural echocardiographic parameters | ||||
Aortic valve area, cm2 | 0.79 ± 0.18 | 0.78 ± 0.19 | 0.80 ± 0.11 | 0.794 |
Aortic valve mean gradient, mmHg | 45.2 ± 12.4 | 44.9 ± 11.6 | 46.5 ± 15.7 | 0.642 |
Aortic valve maximum velocity, m/s | 4.3 ± 0.6 | 4.3 ± 0.6 | 4.3 ± 0.6 | 0.583 |
Left ventricular ejection fraction, % | 54.2 ± 8.4 | 54.8 ± 8.3 | 51.7 ± 8.4 | 0.203 |
Moderate or severe aortic regurgitation, n (%) | 7 (9.1) | 6 (9.7) | 1 (6.7) | 1.000 |
Data are presented as mean ± standard deviation, median [interquartile range], or as number (%).
CMR-RF, cardiac magnetic resonance-regurgitant fraction; COPD, chronic obstructive pulmonary disease; MDRD-GFR, Modification of Diet in Renal Disease—glomerular filtration rate; NYHA, New York Heart Association; STS, Society of Thoracic Surgeons.
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