Table 2 Open in new tab Performance on... | Oxford Academic

Table 2

Open in new tab

Performance on the UnifyPDBAcceptable 5-fold test datasets

	SPRI	EVmutation	FATHMM	LIST	PMUT	Polyphen-2	PROVEAN	Rhapsody
Completeness	1.0	0.711	0.990	0.990	0.987	0.990	0.990	0.941
Recall	0.913	0.902	0.846	0.753	0.747	0.881	0.824	0.822
Specificity	0.828	0.766	0.405	0.766	0.732	0.809	0.817	0.925
Precision	0.902	0.878	0.707	0.846	0.829	0.888	0.884	0.952
Accuracy	0.882	0.854	0.683	0.758	0.742	0.855	0.821	0.859
F-1 score	0.907	0.890	0.771	0.797	0.786	0.884	0.853	0.882
MCC score	0.744	0.676	0.281	0.505	0.466	0.689	0.628	0.721

	SPRI	EVmutation	FATHMM	LIST	PMUT	Polyphen-2	PROVEAN	Rhapsody
Completeness	1.0	0.711	0.990	0.990	0.987	0.990	0.990	0.941
Recall	0.913	0.902	0.846	0.753	0.747	0.881	0.824	0.822
Specificity	0.828	0.766	0.405	0.766	0.732	0.809	0.817	0.925
Precision	0.902	0.878	0.707	0.846	0.829	0.888	0.884	0.952
Accuracy	0.882	0.854	0.683	0.758	0.742	0.855	0.821	0.859
F-1 score	0.907	0.890	0.771	0.797	0.786	0.884	0.853	0.882
MCC score	0.744	0.676	0.281	0.505	0.466	0.689	0.628	0.721

Bold indicates the best metric.

Table 2

Open in new tab

Performance on the UnifyPDBAcceptable 5-fold test datasets

	SPRI	EVmutation	FATHMM	LIST	PMUT	Polyphen-2	PROVEAN	Rhapsody
Completeness	1.0	0.711	0.990	0.990	0.987	0.990	0.990	0.941
Recall	0.913	0.902	0.846	0.753	0.747	0.881	0.824	0.822
Specificity	0.828	0.766	0.405	0.766	0.732	0.809	0.817	0.925
Precision	0.902	0.878	0.707	0.846	0.829	0.888	0.884	0.952
Accuracy	0.882	0.854	0.683	0.758	0.742	0.855	0.821	0.859
F-1 score	0.907	0.890	0.771	0.797	0.786	0.884	0.853	0.882
MCC score	0.744	0.676	0.281	0.505	0.466	0.689	0.628	0.721

	SPRI	EVmutation	FATHMM	LIST	PMUT	Polyphen-2	PROVEAN	Rhapsody
Completeness	1.0	0.711	0.990	0.990	0.987	0.990	0.990	0.941
Recall	0.913	0.902	0.846	0.753	0.747	0.881	0.824	0.822
Specificity	0.828	0.766	0.405	0.766	0.732	0.809	0.817	0.925
Precision	0.902	0.878	0.707	0.846	0.829	0.888	0.884	0.952
Accuracy	0.882	0.854	0.683	0.758	0.742	0.855	0.821	0.859
F-1 score	0.907	0.890	0.771	0.797	0.786	0.884	0.853	0.882
MCC score	0.744	0.676	0.281	0.505	0.466	0.689	0.628	0.721

Bold indicates the best metric.