Table 5 Open in new tab The performance...

Ablation settings	Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
✓				0.5789	0.5611	0.4012	0.4654	0.469	0.4011	0.5108
✓	✓			0.8517	0.5995	0.9206	0.7874	0.8338	0.5948	0.8236
✓	✓	✓		0.8632	0.6619	0.9357	0.7939	0.8467	0.6487	0.8384
✓	✓		✓	0.8492	0.5923	0.9292	0.7817	0.8414	0.5609	0.8303
✓	✓	✓	✓	0.8641	0.6828	0.9329	0.7978	0.8384	0.6614	0.8336

Ablation settings	Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
✓				0.5789	0.5611	0.4012	0.4654	0.469	0.4011	0.5108
✓	✓			0.8517	0.5995	0.9206	0.7874	0.8338	0.5948	0.8236
✓	✓	✓		0.8632	0.6619	0.9357	0.7939	0.8467	0.6487	0.8384
✓	✓		✓	0.8492	0.5923	0.9292	0.7817	0.8414	0.5609	0.8303
✓	✓	✓	✓	0.8641	0.6828	0.9329	0.7978	0.8384	0.6614	0.8336

Table 5

The performance of DAmiRLocGNet on AUC

Ablation settings				Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
a	b	c	d	Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
✓				0.5789	0.5611	0.4012	0.4654	0.469	0.4011	0.5108
✓	✓			0.8517	0.5995	0.9206	0.7874	0.8338	0.5948	0.8236
✓	✓	✓		0.8632	0.6619	0.9357	0.7939	0.8467	0.6487	0.8384
✓	✓		✓	0.8492	0.5923	0.9292	0.7817	0.8414	0.5609	0.8303
✓	✓	✓	✓	0.8641	0.6828	0.9329	0.7978	0.8384	0.6614	0.8336

Ablation settings				Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
a	b	c	d	Cytop	Exos	Nucleo	Nucle	EV	Microv	Mitochon
✓				0.5789	0.5611	0.4012	0.4654	0.469	0.4011	0.5108
✓	✓			0.8517	0.5995	0.9206	0.7874	0.8338	0.5948	0.8236
✓	✓	✓		0.8632	0.6619	0.9357	0.7939	0.8467	0.6487	0.8384
✓	✓		✓	0.8492	0.5923	0.9292	0.7817	0.8414	0.5609	0.8303
✓	✓	✓	✓	0.8641	0.6828	0.9329	0.7978	0.8384	0.6614	0.8336

a: Sequence layer; b: GCN layer; c: miRNA RWR layer; d: disease RWR layer. Cytop: cytoplasm, Exos: exosome, Nucleo: nucleolus, Nucle: nucleus, EV: extracellular vesicle, Microv: microvesicle and Mitochon: mitochondrion.

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