| . | N (%) . |
|---|---|
| Age | |
| 75-94 years | 9 (9.8) |
| 55-74 years | 22 (23.9) |
| Less than 55 years | 61 (66.3) |
| Body mass index* | |
| Obese | 33 (35.9) |
| Overweight | 29 (31.5) |
| Normal | 23 (25.0) |
| Lean | 7 (7.6) |
| Glycemic history | |
| Diabetes | 31 (33.7) |
| Pre-diabetes only | 9 (9.8) |
| Normoglycemia | 52 (56.5) |
| Diagnosis of hypertension | |
| Present | 49 (53.3) |
| Absent | 43 (46.7) |
| Diagnosis of hyperlipidemia | |
| Present | 38 (41.3) |
| Absent | 54 (58.7) |
| Self-reported ancestry | |
| Asian | 12 (13.0) |
| Hispanic/Latino | 14 (15.2) |
| African/Black | 8 (8.7) |
| Hawaiian/Pacific Islander | 1 (1.1) |
| Other | 2 (2.2) |
| Non-Hispanic White | 46 (50.0) |
| Unknown/decline to state | 9 (9.8) |
| . | N (%) . |
|---|---|
| Age | |
| 75-94 years | 9 (9.8) |
| 55-74 years | 22 (23.9) |
| Less than 55 years | 61 (66.3) |
| Body mass index* | |
| Obese | 33 (35.9) |
| Overweight | 29 (31.5) |
| Normal | 23 (25.0) |
| Lean | 7 (7.6) |
| Glycemic history | |
| Diabetes | 31 (33.7) |
| Pre-diabetes only | 9 (9.8) |
| Normoglycemia | 52 (56.5) |
| Diagnosis of hypertension | |
| Present | 49 (53.3) |
| Absent | 43 (46.7) |
| Diagnosis of hyperlipidemia | |
| Present | 38 (41.3) |
| Absent | 54 (58.7) |
| Self-reported ancestry | |
| Asian | 12 (13.0) |
| Hispanic/Latino | 14 (15.2) |
| African/Black | 8 (8.7) |
| Hawaiian/Pacific Islander | 1 (1.1) |
| Other | 2 (2.2) |
| Non-Hispanic White | 46 (50.0) |
| Unknown/decline to state | 9 (9.8) |
*As described in the Methods, Results, and Supplementary Table S1, for n = 64 subjects it was necessary to estimate the pre-alpelisib value of BMI from a post-alpelisib value in their medical chart. Lean was defined as BMI < 20, normal was defined as BMI 20 to <25 (BMI 20 to <23 for Asians), overweight was defined as BMI 25 to <30 (BMI 23 to <27.5 for Asians), and obese was defined as BMI ≥30 (BMI ≥27.5 for Asians).5,6
| . | N (%) . |
|---|---|
| Age | |
| 75-94 years | 9 (9.8) |
| 55-74 years | 22 (23.9) |
| Less than 55 years | 61 (66.3) |
| Body mass index* | |
| Obese | 33 (35.9) |
| Overweight | 29 (31.5) |
| Normal | 23 (25.0) |
| Lean | 7 (7.6) |
| Glycemic history | |
| Diabetes | 31 (33.7) |
| Pre-diabetes only | 9 (9.8) |
| Normoglycemia | 52 (56.5) |
| Diagnosis of hypertension | |
| Present | 49 (53.3) |
| Absent | 43 (46.7) |
| Diagnosis of hyperlipidemia | |
| Present | 38 (41.3) |
| Absent | 54 (58.7) |
| Self-reported ancestry | |
| Asian | 12 (13.0) |
| Hispanic/Latino | 14 (15.2) |
| African/Black | 8 (8.7) |
| Hawaiian/Pacific Islander | 1 (1.1) |
| Other | 2 (2.2) |
| Non-Hispanic White | 46 (50.0) |
| Unknown/decline to state | 9 (9.8) |
| . | N (%) . |
|---|---|
| Age | |
| 75-94 years | 9 (9.8) |
| 55-74 years | 22 (23.9) |
| Less than 55 years | 61 (66.3) |
| Body mass index* | |
| Obese | 33 (35.9) |
| Overweight | 29 (31.5) |
| Normal | 23 (25.0) |
| Lean | 7 (7.6) |
| Glycemic history | |
| Diabetes | 31 (33.7) |
| Pre-diabetes only | 9 (9.8) |
| Normoglycemia | 52 (56.5) |
| Diagnosis of hypertension | |
| Present | 49 (53.3) |
| Absent | 43 (46.7) |
| Diagnosis of hyperlipidemia | |
| Present | 38 (41.3) |
| Absent | 54 (58.7) |
| Self-reported ancestry | |
| Asian | 12 (13.0) |
| Hispanic/Latino | 14 (15.2) |
| African/Black | 8 (8.7) |
| Hawaiian/Pacific Islander | 1 (1.1) |
| Other | 2 (2.2) |
| Non-Hispanic White | 46 (50.0) |
| Unknown/decline to state | 9 (9.8) |
*As described in the Methods, Results, and Supplementary Table S1, for n = 64 subjects it was necessary to estimate the pre-alpelisib value of BMI from a post-alpelisib value in their medical chart. Lean was defined as BMI < 20, normal was defined as BMI 20 to <25 (BMI 20 to <23 for Asians), overweight was defined as BMI 25 to <30 (BMI 23 to <27.5 for Asians), and obese was defined as BMI ≥30 (BMI ≥27.5 for Asians).5,6
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