Table 3 Open in new tab Prevalence and...

Cancer type	Total (N = 188 351)^a	Provided blood (N = 38 799)^a
Anal	45	67	4.0	15	13	4.7
Bladder	321	580	34.7	97	126	46.0
Bone and joint	47	37	2.2	12	11	4.0
Brain, spine and nervous systems	146	208	12.4	22	50	18.2
Breast (female)	2535	1870	190.2	926	415	263.3
Breast (male)	13	19	2.9	<5	<5	1.8
Cervical	232	99	9.8	62	17	60.0
Colorectal	960	969	58.2	275	167	61.2
Gastrointestinal	160	378	22.6	49	68	24.7
Heart and other intrathoracic	31	41	2.4	9	11	4.0
Haematobiliary	42	232	13.8	13	48	17.5
Haematologic	469	956	57.2	139	217	79.3
Lung	280	1049	62.7	80	200	72.9
Lymph node	653	335	20.1	191	77	28.1
Nasal cavity and sinuses	17	22	1.3	6	6	2.2
Ocular	44	42	2.5	10	12	4.4
Oral	240	258	15.4	68	45	16.4
Other urinary	39	69	4.1	8	16	5.8
Ovarian	196	213	21.1	59	43	26.1
Pancreatic	44	281	16.8	14	74	26.9
Prostate	2194	1699	266.3	683	456	441.9
Renal	312	357	21.3	104	73	26.6
Skin (melanoma)	972	834	50.1	315	204	74.9
Throat	75	65	3.9	16	14	5.1
Thyroid and other endocrinal	829	522	31.3	285	93	34.1
Tissues and abdominal cavity	115	121	7.2	34	30	10.9
Uterine	468	540	53.6	176	134	81.8
Other female genital	74	77	7.6	28	14	8.5
Other male genital	180	73	11.0	41	11	10.1

Cancer type

Total (N = 188 351)^a

Provided blood (N = 38 799)^a

Prevalence^b

Incidence^c^,^d

Prevalence^b

Incidence^c

Per 100 000 person-years

Anal

4.0

4.7

Bladder

321

580

34.7

126

46.0

Bone and joint

2.2

4.0

Brain, spine and nervous systems

146

208

12.4

18.2

Breast (female)

2535

1870

190.2

926

415

263.3

Breast (male)

2.9

1.8

Cervical

232

9.8

60.0

Colorectal

960

969

58.2

275

167

61.2

Gastrointestinal

160

378

22.6

24.7

Heart and other intrathoracic

2.4

4.0

Haematobiliary

232

13.8

17.5

Haematologic

469

956

57.2

139

217

79.3

Lung

280

1049

62.7

200

72.9

Lymph node

653

335

20.1

191

28.1

Nasal cavity and sinuses

1.3

2.2

Ocular

2.5

4.4

Oral

240

258

15.4

16.4

Other urinary

4.1

5.8

Ovarian

196

213

21.1

26.1

Pancreatic

281

16.8

26.9

Prostate

2194

1699

266.3

683

456

441.9

Renal

312

357

21.3

104

26.6

Skin (melanoma)

972

834

50.1

315

204

74.9

Throat

3.9

5.1

Thyroid and other endocrinal

829

522

31.3

285

34.1

Tissues and abdominal cavity

115

121

7.2

10.9

Uterine

468

540

53.6

176

134

81.8

Other female genital

7.6

8.5

Other male genital

180

11.0

10.1

Cancer type	Total (N = 188 351)^a	Provided blood (N = 38 799)^a
Anal	45	67	4.0	15	13	4.7
Bladder	321	580	34.7	97	126	46.0
Bone and joint	47	37	2.2	12	11	4.0
Brain, spine and nervous systems	146	208	12.4	22	50	18.2
Breast (female)	2535	1870	190.2	926	415	263.3
Breast (male)	13	19	2.9	<5	<5	1.8
Cervical	232	99	9.8	62	17	60.0
Colorectal	960	969	58.2	275	167	61.2
Gastrointestinal	160	378	22.6	49	68	24.7
Heart and other intrathoracic	31	41	2.4	9	11	4.0
Haematobiliary	42	232	13.8	13	48	17.5
Haematologic	469	956	57.2	139	217	79.3
Lung	280	1049	62.7	80	200	72.9
Lymph node	653	335	20.1	191	77	28.1
Nasal cavity and sinuses	17	22	1.3	6	6	2.2
Ocular	44	42	2.5	10	12	4.4
Oral	240	258	15.4	68	45	16.4
Other urinary	39	69	4.1	8	16	5.8
Ovarian	196	213	21.1	59	43	26.1
Pancreatic	44	281	16.8	14	74	26.9
Prostate	2194	1699	266.3	683	456	441.9
Renal	312	357	21.3	104	73	26.6
Skin (melanoma)	972	834	50.1	315	204	74.9
Throat	75	65	3.9	16	14	5.1
Thyroid and other endocrinal	829	522	31.3	285	93	34.1
Tissues and abdominal cavity	115	121	7.2	34	30	10.9
Uterine	468	540	53.6	176	134	81.8
Other female genital	74	77	7.6	28	14	8.5
Other male genital	180	73	11.0	41	11	10.1

Table 3

Open in new tab

Prevalence and incidence of cancer in the Ontario Health Study, overall and among those who provided a blood sample^a

Cancer type	Total (N = 188 351)^a			Provided blood (N = 38 799)^a
	Prevalence^b	Incidence^c^,^d		Prevalence^b	Incidence^c
	n	n	Per 100 000 person-years	n	n	Per 100 000 person-years
Anal	45	67	4.0	15	13	4.7
Bladder	321	580	34.7	97	126	46.0
Bone and joint	47	37	2.2	12	11	4.0
Brain, spine and nervous systems	146	208	12.4	22	50	18.2
Breast (female)	2535	1870	190.2	926	415	263.3
Breast (male)	13	19	2.9	<5	<5	1.8
Cervical	232	99	9.8	62	17	60.0
Colorectal	960	969	58.2	275	167	61.2
Gastrointestinal	160	378	22.6	49	68	24.7
Heart and other intrathoracic	31	41	2.4	9	11	4.0
Haematobiliary	42	232	13.8	13	48	17.5
Haematologic	469	956	57.2	139	217	79.3
Lung	280	1049	62.7	80	200	72.9
Lymph node	653	335	20.1	191	77	28.1
Nasal cavity and sinuses	17	22	1.3	6	6	2.2
Ocular	44	42	2.5	10	12	4.4
Oral	240	258	15.4	68	45	16.4
Other urinary	39	69	4.1	8	16	5.8
Ovarian	196	213	21.1	59	43	26.1
Pancreatic	44	281	16.8	14	74	26.9
Prostate	2194	1699	266.3	683	456	441.9
Renal	312	357	21.3	104	73	26.6
Skin (melanoma)	972	834	50.1	315	204	74.9
Throat	75	65	3.9	16	14	5.1
Thyroid and other endocrinal	829	522	31.3	285	93	34.1
Tissues and abdominal cavity	115	121	7.2	34	30	10.9
Uterine	468	540	53.6	176	134	81.8
Other female genital	74	77	7.6	28	14	8.5
Other male genital	180	73	11.0	41	11	10.1

Cancer type	Total (N = 188 351)^a			Provided blood (N = 38 799)^a
	Prevalence^b	Incidence^c^,^d		Prevalence^b	Incidence^c
	n	n	Per 100 000 person-years	n	n	Per 100 000 person-years
Anal	45	67	4.0	15	13	4.7
Bladder	321	580	34.7	97	126	46.0
Bone and joint	47	37	2.2	12	11	4.0
Brain, spine and nervous systems	146	208	12.4	22	50	18.2
Breast (female)	2535	1870	190.2	926	415	263.3
Breast (male)	13	19	2.9	<5	<5	1.8
Cervical	232	99	9.8	62	17	60.0
Colorectal	960	969	58.2	275	167	61.2
Gastrointestinal	160	378	22.6	49	68	24.7
Heart and other intrathoracic	31	41	2.4	9	11	4.0
Haematobiliary	42	232	13.8	13	48	17.5
Haematologic	469	956	57.2	139	217	79.3
Lung	280	1049	62.7	80	200	72.9
Lymph node	653	335	20.1	191	77	28.1
Nasal cavity and sinuses	17	22	1.3	6	6	2.2
Ocular	44	42	2.5	10	12	4.4
Oral	240	258	15.4	68	45	16.4
Other urinary	39	69	4.1	8	16	5.8
Ovarian	196	213	21.1	59	43	26.1
Pancreatic	44	281	16.8	14	74	26.9
Prostate	2194	1699	266.3	683	456	441.9
Renal	312	357	21.3	104	73	26.6
Skin (melanoma)	972	834	50.1	315	204	74.9
Throat	75	65	3.9	16	14	5.1
Thyroid and other endocrinal	829	522	31.3	285	93	34.1
Tissues and abdominal cavity	115	121	7.2	34	30	10.9
Uterine	468	540	53.6	176	134	81.8
Other female genital	74	77	7.6	28	14	8.5
Other male genital	180	73	11.0	41	11	10.1

Includes participants who consented to administrative linkages; mean (SD) age in years is 47 (15) overall and 57 (10) among those who provided a blood sample.

Ascertained through linkage with the Ontario Cancer Registry from 1 January 1964 through to date of enrolment; self-reported cancer history is also available.

Ascertained through linkage with the Ontario Cancer Registry covering the period from baseline to 31 March 2021.

Average follow-up time is 8.7 years; 1 634 839 total person-years of observation.

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