Table 2 Open in new tab Regions with...

Location	MNI coordinate	Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Patients > HCs
Insula_R (aal)	42	4	−6	569	1.950	0.18045	0.000106573	12/12	no	0.593
Postcentral_R (aal)	36	−30	56	169	1.611	0.15076	0.000996053	11/12	no	0.758
Cerebellum_9_L (aal)	−8	−48	−40	93	1.664	0.06858	0.000704467	11/12	no	0.081
Angular_L (aal)	−36	−60	34	63	1.490	0.14089	0.002001107	10/12	no	0.982
Caudate_R (aal)	8	10	10	74	1.391	0.05246	0.003449976	11/12	no	0.025
ParaHippocampal_L (aal)	−22	−38	−8	37	1.637	0.15185	0.000835299	11/12	no	0.036
Supp_Motor_Area_R (aal)	6	−2	70	11	1.389	0.12831	0.003506243	6/12	no	0.025
Patients< HCs
Cerebellum_6_L (aal)	−36	−50	−28	386	−1.584	−0.32515	0.001183629	10/12	yes	0.040
Cingulum_Mid_L (aal)	6	−26	28	118	−2.000	−0.18614	0.000073254	12/12	yes	0.586
Cerebellum_Crus1_R (aal)	14	−84	−24	292	−2.025	−0.18724	0.000064254	11/12	no	0.159
Supp_Motor_Area_L (aal)	0	16	44	155	−1.450	−0.23477	0.002647519	10/12	yes	0.098

Location

MNI coordinate

Cluster size

SDM-Z value

Effect size

P-value

Jacknife sensitivity analysis

Heterogeneity

Egger test (P-value)

Patients > HCs

Insula_R (aal)

−6

569

1.950

0.18045

0.000106573

12/12

0.593

Postcentral_R (aal)

−30

169

1.611

0.15076

0.000996053

11/12

0.758

Cerebellum_9_L (aal)

−8

−48

−40

1.664

0.06858

0.000704467

11/12

0.081

Angular_L (aal)

−36

−60

1.490

0.14089

0.002001107

10/12

0.982

Caudate_R (aal)

1.391

0.05246

0.003449976

11/12

0.025

ParaHippocampal_L (aal)

−22

−38

−8

1.637

0.15185

0.000835299

11/12

0.036

Supp_Motor_Area_R (aal)

−2

1.389

0.12831

0.003506243

6/12

0.025

Patients< HCs

Cerebellum_6_L (aal)

−36

−50

−28

386

−1.584

−0.32515

0.001183629

10/12

yes

0.040

Cingulum_Mid_L (aal)

−26

118

−2.000

−0.18614

0.000073254

12/12

yes

0.586

Cerebellum_Crus1_R (aal)

−84

−24

292

−2.025

−0.18724

0.000064254

11/12

0.159

Supp_Motor_Area_L (aal)

155

−1.450

−0.23477

0.002647519

10/12

yes

0.098

Location	MNI coordinate	Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Patients > HCs
Insula_R (aal)	42	4	−6	569	1.950	0.18045	0.000106573	12/12	no	0.593
Postcentral_R (aal)	36	−30	56	169	1.611	0.15076	0.000996053	11/12	no	0.758
Cerebellum_9_L (aal)	−8	−48	−40	93	1.664	0.06858	0.000704467	11/12	no	0.081
Angular_L (aal)	−36	−60	34	63	1.490	0.14089	0.002001107	10/12	no	0.982
Caudate_R (aal)	8	10	10	74	1.391	0.05246	0.003449976	11/12	no	0.025
ParaHippocampal_L (aal)	−22	−38	−8	37	1.637	0.15185	0.000835299	11/12	no	0.036
Supp_Motor_Area_R (aal)	6	−2	70	11	1.389	0.12831	0.003506243	6/12	no	0.025
Patients< HCs
Cerebellum_6_L (aal)	−36	−50	−28	386	−1.584	−0.32515	0.001183629	10/12	yes	0.040
Cingulum_Mid_L (aal)	6	−26	28	118	−2.000	−0.18614	0.000073254	12/12	yes	0.586
Cerebellum_Crus1_R (aal)	14	−84	−24	292	−2.025	−0.18724	0.000064254	11/12	no	0.159
Supp_Motor_Area_L (aal)	0	16	44	155	−1.450	−0.23477	0.002647519	10/12	yes	0.098

Table 2

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Regions with abnormal regional spontaneous brain activity in poststroke aphasia patients relative to HCs.

Location	MNI coordinate			Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Location	x	y	z	Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Patients > HCs
Insula_R (aal)	42	4	−6	569	1.950	0.18045	0.000106573	12/12	no	0.593
Postcentral_R (aal)	36	−30	56	169	1.611	0.15076	0.000996053	11/12	no	0.758
Cerebellum_9_L (aal)	−8	−48	−40	93	1.664	0.06858	0.000704467	11/12	no	0.081
Angular_L (aal)	−36	−60	34	63	1.490	0.14089	0.002001107	10/12	no	0.982
Caudate_R (aal)	8	10	10	74	1.391	0.05246	0.003449976	11/12	no	0.025
ParaHippocampal_L (aal)	−22	−38	−8	37	1.637	0.15185	0.000835299	11/12	no	0.036
Supp_Motor_Area_R (aal)	6	−2	70	11	1.389	0.12831	0.003506243	6/12	no	0.025
Patients< HCs
Cerebellum_6_L (aal)	−36	−50	−28	386	−1.584	−0.32515	0.001183629	10/12	yes	0.040
Cingulum_Mid_L (aal)	6	−26	28	118	−2.000	−0.18614	0.000073254	12/12	yes	0.586
Cerebellum_Crus1_R (aal)	14	−84	−24	292	−2.025	−0.18724	0.000064254	11/12	no	0.159
Supp_Motor_Area_L (aal)	0	16	44	155	−1.450	−0.23477	0.002647519	10/12	yes	0.098

Location	MNI coordinate			Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Location	x	y	z	Cluster size	SDM-Z value	Effect size	P-value	Jacknife sensitivity analysis	Heterogeneity	Egger test (P-value)
Patients > HCs
Insula_R (aal)	42	4	−6	569	1.950	0.18045	0.000106573	12/12	no	0.593
Postcentral_R (aal)	36	−30	56	169	1.611	0.15076	0.000996053	11/12	no	0.758
Cerebellum_9_L (aal)	−8	−48	−40	93	1.664	0.06858	0.000704467	11/12	no	0.081
Angular_L (aal)	−36	−60	34	63	1.490	0.14089	0.002001107	10/12	no	0.982
Caudate_R (aal)	8	10	10	74	1.391	0.05246	0.003449976	11/12	no	0.025
ParaHippocampal_L (aal)	−22	−38	−8	37	1.637	0.15185	0.000835299	11/12	no	0.036
Supp_Motor_Area_R (aal)	6	−2	70	11	1.389	0.12831	0.003506243	6/12	no	0.025
Patients< HCs
Cerebellum_6_L (aal)	−36	−50	−28	386	−1.584	−0.32515	0.001183629	10/12	yes	0.040
Cingulum_Mid_L (aal)	6	−26	28	118	−2.000	−0.18614	0.000073254	12/12	yes	0.586
Cerebellum_Crus1_R (aal)	14	−84	−24	292	−2.025	−0.18724	0.000064254	11/12	no	0.159
Supp_Motor_Area_L (aal)	0	16	44	155	−1.450	−0.23477	0.002647519	10/12	yes	0.098

Abbreviations: aal, anatomical automatic labeling; Angular_L, left angular gyrus; Caudate_R, right caudate nucleus; Cerebellum_Crus1_R, right cerebellar crus I; Cerebellum_9_L, left cerebellar lobule IX; Cerebellum_6_L, left cerebellar lobule VI; Cingulum_Mid_L, left median cingulate and paracingulate gyri; Insula_R, right insula; ParaHippocampal_L, left parahippocampal gyrus; Postcentral_R, right postcentral gyrus; SDM, seed-based d mapping; Supp_Motor_Area_L, left supplementary motor area; Supp_Motor_Area_R, right supplementary motor area.

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