Table 1.
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Clinical and histological characteristics of cutaneous vasculitis in SLE (n = 39)

CharacteristicValue, n (%)
Vasculitis cutaneous features
 Palpable purpura21 (54)
 Urticarial lesions18 (46)
 Erythematous papules/macules12 (31)
 Ulcerated/necrotic lesions8 (21)
 Livedo reticularis5 (13)
 Nodular lesions1 (2.6)
 Association of lesions type17 (44)
Topography of cutaneous lesions
 Legs/lower limbs33 (85)
 Trunk/abdomen13 (33)
 Arms/upper limbs11 (28)
 Fingertips and/or palms8 (21)
 Face0 (0)
 Association of locations18 (46)
Associated features
 Angioedema3 (8)
 Episcleritis3 (8)
Vasculitis visceral involvement
 Mononeuritis multiplex8 (21)
 Membranoproliferative glomerulonephritis1 (2)
 Muscle involvement1 (2)
 Digestive involvement1 (2)
Biological and immunological features
 Elevated CRP level (>5 mg/l)20/33 (61)a
 Cryoglobulinaemiab15/32 (47)a
 Anti-C1q positive2/9 (22)a
 ANCA-positive0/33 (0)a
Histological features
 Inflammatory cell infiltration39 (100)
 predominant neutrophilic infiltrates22 (56)
 predominant lymphocytic infiltrates15 (38)
 predominant eosinophilic infiltrates0 (0)
 no predominant infiltrate2 (5)
 Leucocytoclasia33 (85)
 Vascular fibrinous necrosis20 (51)
Direct Immunofluorescence features
 Perivascular C3 deposits13/21 (62)a
 Perivascular Ig deposits8/21 (38)a
 Perivascular C1q deposits5/21 (24)a
CharacteristicValue, n (%)
Vasculitis cutaneous features
 Palpable purpura21 (54)
 Urticarial lesions18 (46)
 Erythematous papules/macules12 (31)
 Ulcerated/necrotic lesions8 (21)
 Livedo reticularis5 (13)
 Nodular lesions1 (2.6)
 Association of lesions type17 (44)
Topography of cutaneous lesions
 Legs/lower limbs33 (85)
 Trunk/abdomen13 (33)
 Arms/upper limbs11 (28)
 Fingertips and/or palms8 (21)
 Face0 (0)
 Association of locations18 (46)
Associated features
 Angioedema3 (8)
 Episcleritis3 (8)
Vasculitis visceral involvement
 Mononeuritis multiplex8 (21)
 Membranoproliferative glomerulonephritis1 (2)
 Muscle involvement1 (2)
 Digestive involvement1 (2)
Biological and immunological features
 Elevated CRP level (>5 mg/l)20/33 (61)a
 Cryoglobulinaemiab15/32 (47)a
 Anti-C1q positive2/9 (22)a
 ANCA-positive0/33 (0)a
Histological features
 Inflammatory cell infiltration39 (100)
 predominant neutrophilic infiltrates22 (56)
 predominant lymphocytic infiltrates15 (38)
 predominant eosinophilic infiltrates0 (0)
 no predominant infiltrate2 (5)
 Leucocytoclasia33 (85)
 Vascular fibrinous necrosis20 (51)
Direct Immunofluorescence features
 Perivascular C3 deposits13/21 (62)a
 Perivascular Ig deposits8/21 (38)a
 Perivascular C1q deposits5/21 (24)a
a

Positive assay/number of patients assessed.

b

n = 6 type II, n = 5 type III, n = 4 untyped cryoglobulinaemia.

Table 1.
Open in new tab

Clinical and histological characteristics of cutaneous vasculitis in SLE (n = 39)

CharacteristicValue, n (%)
Vasculitis cutaneous features
 Palpable purpura21 (54)
 Urticarial lesions18 (46)
 Erythematous papules/macules12 (31)
 Ulcerated/necrotic lesions8 (21)
 Livedo reticularis5 (13)
 Nodular lesions1 (2.6)
 Association of lesions type17 (44)
Topography of cutaneous lesions
 Legs/lower limbs33 (85)
 Trunk/abdomen13 (33)
 Arms/upper limbs11 (28)
 Fingertips and/or palms8 (21)
 Face0 (0)
 Association of locations18 (46)
Associated features
 Angioedema3 (8)
 Episcleritis3 (8)
Vasculitis visceral involvement
 Mononeuritis multiplex8 (21)
 Membranoproliferative glomerulonephritis1 (2)
 Muscle involvement1 (2)
 Digestive involvement1 (2)
Biological and immunological features
 Elevated CRP level (>5 mg/l)20/33 (61)a
 Cryoglobulinaemiab15/32 (47)a
 Anti-C1q positive2/9 (22)a
 ANCA-positive0/33 (0)a
Histological features
 Inflammatory cell infiltration39 (100)
 predominant neutrophilic infiltrates22 (56)
 predominant lymphocytic infiltrates15 (38)
 predominant eosinophilic infiltrates0 (0)
 no predominant infiltrate2 (5)
 Leucocytoclasia33 (85)
 Vascular fibrinous necrosis20 (51)
Direct Immunofluorescence features
 Perivascular C3 deposits13/21 (62)a
 Perivascular Ig deposits8/21 (38)a
 Perivascular C1q deposits5/21 (24)a
CharacteristicValue, n (%)
Vasculitis cutaneous features
 Palpable purpura21 (54)
 Urticarial lesions18 (46)
 Erythematous papules/macules12 (31)
 Ulcerated/necrotic lesions8 (21)
 Livedo reticularis5 (13)
 Nodular lesions1 (2.6)
 Association of lesions type17 (44)
Topography of cutaneous lesions
 Legs/lower limbs33 (85)
 Trunk/abdomen13 (33)
 Arms/upper limbs11 (28)
 Fingertips and/or palms8 (21)
 Face0 (0)
 Association of locations18 (46)
Associated features
 Angioedema3 (8)
 Episcleritis3 (8)
Vasculitis visceral involvement
 Mononeuritis multiplex8 (21)
 Membranoproliferative glomerulonephritis1 (2)
 Muscle involvement1 (2)
 Digestive involvement1 (2)
Biological and immunological features
 Elevated CRP level (>5 mg/l)20/33 (61)a
 Cryoglobulinaemiab15/32 (47)a
 Anti-C1q positive2/9 (22)a
 ANCA-positive0/33 (0)a
Histological features
 Inflammatory cell infiltration39 (100)
 predominant neutrophilic infiltrates22 (56)
 predominant lymphocytic infiltrates15 (38)
 predominant eosinophilic infiltrates0 (0)
 no predominant infiltrate2 (5)
 Leucocytoclasia33 (85)
 Vascular fibrinous necrosis20 (51)
Direct Immunofluorescence features
 Perivascular C3 deposits13/21 (62)a
 Perivascular Ig deposits8/21 (38)a
 Perivascular C1q deposits5/21 (24)a
a

Positive assay/number of patients assessed.

b

n = 6 type II, n = 5 type III, n = 4 untyped cryoglobulinaemia.

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