Descriptive Statistics of Study Population and Incidence of Newly Diagnosed Active Tuberculosis (TB): Adults Tested for Hepatitis C Virus Antibodies in Georgia Between 1 January 2015 and 30 September 2020, Without Prior TB Diagnosis
Demographic Characteristics . | Total . | New Active TB . | PYs . | TB IR per 100 000 PYs . | ||
---|---|---|---|---|---|---|
n . | Column (%) . | n . | Row (%) . | |||
Total cohort | 1 828 808 | 100 | 3163 | 0.17 | 4 212 327 | 75.1 |
Sex | ||||||
ȃMale | 825 081 | 45 | 2085 | 0.25 | 1 962 556 | 106.2 |
ȃFemale | 1 003 727 | 55 | 1078 | 0.11 | 2 249 771 | 47.9 |
Year of first HCV antibody testing | ||||||
ȃ<2015 | 68 140 | 4 | 243 | 0.36 | 388 635 | 62.5 |
ȃ2015 | 68 540 | 4 | 224 | 0.33 | 348 813 | 64.2 |
ȃ2016 | 170 503 | 9 | 379 | 0.22 | 671 155 | 56.5 |
ȃ2017 | 433 011 | 24 | 904 | 0.21 | 1 307 516 | 69.1 |
ȃ2018 | 394 774 | 22 | 688 | 0.17 | 842 728 | 81.6 |
ȃ2019 | 494 685 | 27 | 539 | 0.11 | 580 092 | 92.9 |
ȃ2020a | 199 155 | 11 | 186 | 0.09 | 73 388 | 253.4 |
Screening group | ||||||
ȃBirth registry | 114 560 | 6 | 102 | 0.09 | 331 484 | 30.8 |
ȃBlood bank | 187 295 | 10 | 303 | 0.16 | 778 103 | 38.9 |
ȃHarm reduction Network | 13 114 | 1 | 18 | 0.14 | 27 843 | 64.6 |
ȃInpatient | 239 624 | 13 | 570 | 0.24 | 684 593 | 83.3 |
ȃNCDC | 162 061 | 9 | 324 | 0.20 | 459 197 | 70.6 |
ȃOutpatient clinics | 987 046 | 54 | 1434 | 0.15 | 1 491 207 | 96.2 |
ȃPeople who are incarcerated | 8770 | 0 | 71 | 0.81 | 30 687 | 231.4 |
ȃMilitary recruits | 24 200 | 1 | 46 | 0.19 | 82 980 | 55.4 |
ȃTbilisi city hall | 25 795 | 1 | 41 | 0.16 | 115 288 | 35.6 |
ȃMissing | 66 343 | 4 | 254 | 0.38 | 210 945 | 120.4 |
Region of the first screening | ||||||
ȃTbilisi | 815 350 | 45 | 1576 | 0.19 | 2 209 702 | 71.3 |
ȃOther | 980 407 | 54 | 1492 | 0.15 | 1 907 664 | 78.2 |
ȃMissing | 33 051 | 2 | 95 | 0.29 | 94 960 | 100.0 |
At least 1 positive HCV antibody test | ||||||
ȃYes | 120 791 | 7 | 664 | 0.55 | 364 830 | 182.0 |
ȃNo | 1 708 017 | 93 | 2499 | 0.15 | 3 847 496 | 65.0 |
Demographic Characteristics . | Total . | New Active TB . | PYs . | TB IR per 100 000 PYs . | ||
---|---|---|---|---|---|---|
n . | Column (%) . | n . | Row (%) . | |||
Total cohort | 1 828 808 | 100 | 3163 | 0.17 | 4 212 327 | 75.1 |
Sex | ||||||
ȃMale | 825 081 | 45 | 2085 | 0.25 | 1 962 556 | 106.2 |
ȃFemale | 1 003 727 | 55 | 1078 | 0.11 | 2 249 771 | 47.9 |
Year of first HCV antibody testing | ||||||
ȃ<2015 | 68 140 | 4 | 243 | 0.36 | 388 635 | 62.5 |
ȃ2015 | 68 540 | 4 | 224 | 0.33 | 348 813 | 64.2 |
ȃ2016 | 170 503 | 9 | 379 | 0.22 | 671 155 | 56.5 |
ȃ2017 | 433 011 | 24 | 904 | 0.21 | 1 307 516 | 69.1 |
ȃ2018 | 394 774 | 22 | 688 | 0.17 | 842 728 | 81.6 |
ȃ2019 | 494 685 | 27 | 539 | 0.11 | 580 092 | 92.9 |
ȃ2020a | 199 155 | 11 | 186 | 0.09 | 73 388 | 253.4 |
Screening group | ||||||
ȃBirth registry | 114 560 | 6 | 102 | 0.09 | 331 484 | 30.8 |
ȃBlood bank | 187 295 | 10 | 303 | 0.16 | 778 103 | 38.9 |
ȃHarm reduction Network | 13 114 | 1 | 18 | 0.14 | 27 843 | 64.6 |
ȃInpatient | 239 624 | 13 | 570 | 0.24 | 684 593 | 83.3 |
ȃNCDC | 162 061 | 9 | 324 | 0.20 | 459 197 | 70.6 |
ȃOutpatient clinics | 987 046 | 54 | 1434 | 0.15 | 1 491 207 | 96.2 |
ȃPeople who are incarcerated | 8770 | 0 | 71 | 0.81 | 30 687 | 231.4 |
ȃMilitary recruits | 24 200 | 1 | 46 | 0.19 | 82 980 | 55.4 |
ȃTbilisi city hall | 25 795 | 1 | 41 | 0.16 | 115 288 | 35.6 |
ȃMissing | 66 343 | 4 | 254 | 0.38 | 210 945 | 120.4 |
Region of the first screening | ||||||
ȃTbilisi | 815 350 | 45 | 1576 | 0.19 | 2 209 702 | 71.3 |
ȃOther | 980 407 | 54 | 1492 | 0.15 | 1 907 664 | 78.2 |
ȃMissing | 33 051 | 2 | 95 | 0.29 | 94 960 | 100.0 |
At least 1 positive HCV antibody test | ||||||
ȃYes | 120 791 | 7 | 664 | 0.55 | 364 830 | 182.0 |
ȃNo | 1 708 017 | 93 | 2499 | 0.15 | 3 847 496 | 65.0 |
Abbreviations: anti-HCV, antibodies against hepatitis C virus; HCV, hepatitis C virus; IR, incidence rate; NCDC, National Center for Disease Control; PY, person-year; TB, tuberculosis.
The high incidence rate of TB in 2020 is likely caused by the pandemic-related lockdowns in the first half of the year (March–May). Anti-HCV testing was lower in early months of 2020 and increased in summer, which caused the number of people included in the analysis for 2020 to increase but their contribution to person-time was very short and resulted in a small denominator, increasing the rate.
Descriptive Statistics of Study Population and Incidence of Newly Diagnosed Active Tuberculosis (TB): Adults Tested for Hepatitis C Virus Antibodies in Georgia Between 1 January 2015 and 30 September 2020, Without Prior TB Diagnosis
Demographic Characteristics . | Total . | New Active TB . | PYs . | TB IR per 100 000 PYs . | ||
---|---|---|---|---|---|---|
n . | Column (%) . | n . | Row (%) . | |||
Total cohort | 1 828 808 | 100 | 3163 | 0.17 | 4 212 327 | 75.1 |
Sex | ||||||
ȃMale | 825 081 | 45 | 2085 | 0.25 | 1 962 556 | 106.2 |
ȃFemale | 1 003 727 | 55 | 1078 | 0.11 | 2 249 771 | 47.9 |
Year of first HCV antibody testing | ||||||
ȃ<2015 | 68 140 | 4 | 243 | 0.36 | 388 635 | 62.5 |
ȃ2015 | 68 540 | 4 | 224 | 0.33 | 348 813 | 64.2 |
ȃ2016 | 170 503 | 9 | 379 | 0.22 | 671 155 | 56.5 |
ȃ2017 | 433 011 | 24 | 904 | 0.21 | 1 307 516 | 69.1 |
ȃ2018 | 394 774 | 22 | 688 | 0.17 | 842 728 | 81.6 |
ȃ2019 | 494 685 | 27 | 539 | 0.11 | 580 092 | 92.9 |
ȃ2020a | 199 155 | 11 | 186 | 0.09 | 73 388 | 253.4 |
Screening group | ||||||
ȃBirth registry | 114 560 | 6 | 102 | 0.09 | 331 484 | 30.8 |
ȃBlood bank | 187 295 | 10 | 303 | 0.16 | 778 103 | 38.9 |
ȃHarm reduction Network | 13 114 | 1 | 18 | 0.14 | 27 843 | 64.6 |
ȃInpatient | 239 624 | 13 | 570 | 0.24 | 684 593 | 83.3 |
ȃNCDC | 162 061 | 9 | 324 | 0.20 | 459 197 | 70.6 |
ȃOutpatient clinics | 987 046 | 54 | 1434 | 0.15 | 1 491 207 | 96.2 |
ȃPeople who are incarcerated | 8770 | 0 | 71 | 0.81 | 30 687 | 231.4 |
ȃMilitary recruits | 24 200 | 1 | 46 | 0.19 | 82 980 | 55.4 |
ȃTbilisi city hall | 25 795 | 1 | 41 | 0.16 | 115 288 | 35.6 |
ȃMissing | 66 343 | 4 | 254 | 0.38 | 210 945 | 120.4 |
Region of the first screening | ||||||
ȃTbilisi | 815 350 | 45 | 1576 | 0.19 | 2 209 702 | 71.3 |
ȃOther | 980 407 | 54 | 1492 | 0.15 | 1 907 664 | 78.2 |
ȃMissing | 33 051 | 2 | 95 | 0.29 | 94 960 | 100.0 |
At least 1 positive HCV antibody test | ||||||
ȃYes | 120 791 | 7 | 664 | 0.55 | 364 830 | 182.0 |
ȃNo | 1 708 017 | 93 | 2499 | 0.15 | 3 847 496 | 65.0 |
Demographic Characteristics . | Total . | New Active TB . | PYs . | TB IR per 100 000 PYs . | ||
---|---|---|---|---|---|---|
n . | Column (%) . | n . | Row (%) . | |||
Total cohort | 1 828 808 | 100 | 3163 | 0.17 | 4 212 327 | 75.1 |
Sex | ||||||
ȃMale | 825 081 | 45 | 2085 | 0.25 | 1 962 556 | 106.2 |
ȃFemale | 1 003 727 | 55 | 1078 | 0.11 | 2 249 771 | 47.9 |
Year of first HCV antibody testing | ||||||
ȃ<2015 | 68 140 | 4 | 243 | 0.36 | 388 635 | 62.5 |
ȃ2015 | 68 540 | 4 | 224 | 0.33 | 348 813 | 64.2 |
ȃ2016 | 170 503 | 9 | 379 | 0.22 | 671 155 | 56.5 |
ȃ2017 | 433 011 | 24 | 904 | 0.21 | 1 307 516 | 69.1 |
ȃ2018 | 394 774 | 22 | 688 | 0.17 | 842 728 | 81.6 |
ȃ2019 | 494 685 | 27 | 539 | 0.11 | 580 092 | 92.9 |
ȃ2020a | 199 155 | 11 | 186 | 0.09 | 73 388 | 253.4 |
Screening group | ||||||
ȃBirth registry | 114 560 | 6 | 102 | 0.09 | 331 484 | 30.8 |
ȃBlood bank | 187 295 | 10 | 303 | 0.16 | 778 103 | 38.9 |
ȃHarm reduction Network | 13 114 | 1 | 18 | 0.14 | 27 843 | 64.6 |
ȃInpatient | 239 624 | 13 | 570 | 0.24 | 684 593 | 83.3 |
ȃNCDC | 162 061 | 9 | 324 | 0.20 | 459 197 | 70.6 |
ȃOutpatient clinics | 987 046 | 54 | 1434 | 0.15 | 1 491 207 | 96.2 |
ȃPeople who are incarcerated | 8770 | 0 | 71 | 0.81 | 30 687 | 231.4 |
ȃMilitary recruits | 24 200 | 1 | 46 | 0.19 | 82 980 | 55.4 |
ȃTbilisi city hall | 25 795 | 1 | 41 | 0.16 | 115 288 | 35.6 |
ȃMissing | 66 343 | 4 | 254 | 0.38 | 210 945 | 120.4 |
Region of the first screening | ||||||
ȃTbilisi | 815 350 | 45 | 1576 | 0.19 | 2 209 702 | 71.3 |
ȃOther | 980 407 | 54 | 1492 | 0.15 | 1 907 664 | 78.2 |
ȃMissing | 33 051 | 2 | 95 | 0.29 | 94 960 | 100.0 |
At least 1 positive HCV antibody test | ||||||
ȃYes | 120 791 | 7 | 664 | 0.55 | 364 830 | 182.0 |
ȃNo | 1 708 017 | 93 | 2499 | 0.15 | 3 847 496 | 65.0 |
Abbreviations: anti-HCV, antibodies against hepatitis C virus; HCV, hepatitis C virus; IR, incidence rate; NCDC, National Center for Disease Control; PY, person-year; TB, tuberculosis.
The high incidence rate of TB in 2020 is likely caused by the pandemic-related lockdowns in the first half of the year (March–May). Anti-HCV testing was lower in early months of 2020 and increased in summer, which caused the number of people included in the analysis for 2020 to increase but their contribution to person-time was very short and resulted in a small denominator, increasing the rate.
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