Neuroendocrine profiles and rates of cryptorchidism/micropenis of isolated hypogonadotropic hypogonadism cohort by pubertal status (n = 242)
. | Absent puberty (TV < 4 mL) n = 144 . | Partial puberty (TV≥4 mL) n = 98 . |
---|---|---|
Cryptorchidism (n, %) | 42 (29%) | 18 (18%) |
Micropenis (n, %) | 40 (28%)a | 11 (11%) |
Apulsatile LH secretion (n, %) | 134/144 (93%) | 51/98 (52%) |
ȃDetectable LH (n, %) | 17/134 (13%) | 16/51 (31%) |
ȃȃRange, IU/L | 1.62-9.10 | 1.70-4.50 |
ȃȃMedian, IU/L | 2.35 | 2.60 |
ȃȃMean ± SD, IU/L | 2.89 ± 1.85 | 2.88 ± 0.88 |
ȃDetectable FSH (n, %) | 27/134 (20%) | 17/51 (33%) |
ȃȃRange, IU/L | 1.61-13.10 | 1.64-3.90 |
ȃȃMedian, IU/L | 2.30 | 1.80 |
ȃȃMean ± SD, IU/L | 3.08 ± 2.40 | 2.07 ± 0.58 |
pulsatile LH secretion | 10/144 (7%) | 47/98 (48%) |
ȃDetectable LH (n, %) | 10/10 (100%) | 47/47 (100%) |
ȃȃRange, IU/L | 2.70-10.20 | 1.70-12.40 |
ȃȃMedian, IU/L | 3.60 | 4.00 |
ȃȃMean ± SD, IU/L | 4.56 ± 2.29 | 4.81 ± 2.52 |
ȃDetectable FSH (n, %) | 9/10 (90%) | 45/47 (96%) |
ȃȃRange, IU/L | 2.00-6.30 | 1.70-13.60 |
ȃȃMedian, IU/L | 5.05 | 3.96 |
ȃȃMean ± SD, IU/L | 4.50 ± 1.76 | 5.12 ± 2.92 |
. | Absent puberty (TV < 4 mL) n = 144 . | Partial puberty (TV≥4 mL) n = 98 . |
---|---|---|
Cryptorchidism (n, %) | 42 (29%) | 18 (18%) |
Micropenis (n, %) | 40 (28%)a | 11 (11%) |
Apulsatile LH secretion (n, %) | 134/144 (93%) | 51/98 (52%) |
ȃDetectable LH (n, %) | 17/134 (13%) | 16/51 (31%) |
ȃȃRange, IU/L | 1.62-9.10 | 1.70-4.50 |
ȃȃMedian, IU/L | 2.35 | 2.60 |
ȃȃMean ± SD, IU/L | 2.89 ± 1.85 | 2.88 ± 0.88 |
ȃDetectable FSH (n, %) | 27/134 (20%) | 17/51 (33%) |
ȃȃRange, IU/L | 1.61-13.10 | 1.64-3.90 |
ȃȃMedian, IU/L | 2.30 | 1.80 |
ȃȃMean ± SD, IU/L | 3.08 ± 2.40 | 2.07 ± 0.58 |
pulsatile LH secretion | 10/144 (7%) | 47/98 (48%) |
ȃDetectable LH (n, %) | 10/10 (100%) | 47/47 (100%) |
ȃȃRange, IU/L | 2.70-10.20 | 1.70-12.40 |
ȃȃMedian, IU/L | 3.60 | 4.00 |
ȃȃMean ± SD, IU/L | 4.56 ± 2.29 | 4.81 ± 2.52 |
ȃDetectable FSH (n, %) | 9/10 (90%) | 45/47 (96%) |
ȃȃRange, IU/L | 2.00-6.30 | 1.70-13.60 |
ȃȃMedian, IU/L | 5.05 | 3.96 |
ȃȃMean ± SD, IU/L | 4.50 ± 1.76 | 5.12 ± 2.92 |
Abbreviations: FSH, follicle-stimulating hormone; LH, luteinizing hormone; TV, testicular volume.
P less than .05.
Neuroendocrine profiles and rates of cryptorchidism/micropenis of isolated hypogonadotropic hypogonadism cohort by pubertal status (n = 242)
. | Absent puberty (TV < 4 mL) n = 144 . | Partial puberty (TV≥4 mL) n = 98 . |
---|---|---|
Cryptorchidism (n, %) | 42 (29%) | 18 (18%) |
Micropenis (n, %) | 40 (28%)a | 11 (11%) |
Apulsatile LH secretion (n, %) | 134/144 (93%) | 51/98 (52%) |
ȃDetectable LH (n, %) | 17/134 (13%) | 16/51 (31%) |
ȃȃRange, IU/L | 1.62-9.10 | 1.70-4.50 |
ȃȃMedian, IU/L | 2.35 | 2.60 |
ȃȃMean ± SD, IU/L | 2.89 ± 1.85 | 2.88 ± 0.88 |
ȃDetectable FSH (n, %) | 27/134 (20%) | 17/51 (33%) |
ȃȃRange, IU/L | 1.61-13.10 | 1.64-3.90 |
ȃȃMedian, IU/L | 2.30 | 1.80 |
ȃȃMean ± SD, IU/L | 3.08 ± 2.40 | 2.07 ± 0.58 |
pulsatile LH secretion | 10/144 (7%) | 47/98 (48%) |
ȃDetectable LH (n, %) | 10/10 (100%) | 47/47 (100%) |
ȃȃRange, IU/L | 2.70-10.20 | 1.70-12.40 |
ȃȃMedian, IU/L | 3.60 | 4.00 |
ȃȃMean ± SD, IU/L | 4.56 ± 2.29 | 4.81 ± 2.52 |
ȃDetectable FSH (n, %) | 9/10 (90%) | 45/47 (96%) |
ȃȃRange, IU/L | 2.00-6.30 | 1.70-13.60 |
ȃȃMedian, IU/L | 5.05 | 3.96 |
ȃȃMean ± SD, IU/L | 4.50 ± 1.76 | 5.12 ± 2.92 |
. | Absent puberty (TV < 4 mL) n = 144 . | Partial puberty (TV≥4 mL) n = 98 . |
---|---|---|
Cryptorchidism (n, %) | 42 (29%) | 18 (18%) |
Micropenis (n, %) | 40 (28%)a | 11 (11%) |
Apulsatile LH secretion (n, %) | 134/144 (93%) | 51/98 (52%) |
ȃDetectable LH (n, %) | 17/134 (13%) | 16/51 (31%) |
ȃȃRange, IU/L | 1.62-9.10 | 1.70-4.50 |
ȃȃMedian, IU/L | 2.35 | 2.60 |
ȃȃMean ± SD, IU/L | 2.89 ± 1.85 | 2.88 ± 0.88 |
ȃDetectable FSH (n, %) | 27/134 (20%) | 17/51 (33%) |
ȃȃRange, IU/L | 1.61-13.10 | 1.64-3.90 |
ȃȃMedian, IU/L | 2.30 | 1.80 |
ȃȃMean ± SD, IU/L | 3.08 ± 2.40 | 2.07 ± 0.58 |
pulsatile LH secretion | 10/144 (7%) | 47/98 (48%) |
ȃDetectable LH (n, %) | 10/10 (100%) | 47/47 (100%) |
ȃȃRange, IU/L | 2.70-10.20 | 1.70-12.40 |
ȃȃMedian, IU/L | 3.60 | 4.00 |
ȃȃMean ± SD, IU/L | 4.56 ± 2.29 | 4.81 ± 2.52 |
ȃDetectable FSH (n, %) | 9/10 (90%) | 45/47 (96%) |
ȃȃRange, IU/L | 2.00-6.30 | 1.70-13.60 |
ȃȃMedian, IU/L | 5.05 | 3.96 |
ȃȃMean ± SD, IU/L | 4.50 ± 1.76 | 5.12 ± 2.92 |
Abbreviations: FSH, follicle-stimulating hormone; LH, luteinizing hormone; TV, testicular volume.
P less than .05.
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