| Method . | Driver pathways . | Number . |
|---|---|---|
| Dendrix | Atypical NF-|$\kappa $|B pathway, FOXA1 transcription factor network | 8 |
| FOXA2 and FOXA3 transcription factor networks, BMP receptor signaling | ||
| Wnt signaling network, p38 MAPK signaling pathway, Ceramide signaling pathway | ||
| Validated transcriptional targets of |$\delta $|Np63 isoforms | ||
| MDPfinder | Nectin adhesion pathway, ErbB receptor signaling network, mTOR signaling pathway | 8 |
| FOXA2 and FOXA3 transcription factor networks, BARD1 signaling events | ||
| Wnt signaling network, FOXA1 transcription factor network, Regulation of RhoA activity | ||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||
| Multi-Dendrix | Arf1 pathway, p53 pathway, BMP receptor signaling, LKB1 signaling events | 11 |
| ATM pathway, Wnt signaling network, C-MYC pathway, Notch signaling pathway | ||
| IL2 signaling events mediated by STAT5, ErbB receptor signaling network | ||
| FOXA2 and FOXA3 transcription factor networks | ||
| CoMDP | Nectin adhesion pathway, PLK3 signaling events, Wnt signaling network | 11 |
| AP-1 transcription factor network, FOXA1 transcription factor network | ||
| FGF signaling pathway, Atypical NF-|$\kappa $|B pathway, PLK1 signaling events | ||
| ErbB receptor signaling network, IL2 signaling events mediated by STAT5 | ||
| Signaling events mediated by the Hedgehog family | ||
| MCSS | E-cadherin signaling in keratinocytes, N-cadherin signaling events | 12 |
| Canonical NF-|$\kappa $|B pathway, Notch signaling pathway, p53 pathway | ||
| FOXA2 and FOXA3 transcription factor networks, LKB1 signaling events | ||
| C-MYC pathway, Wnt signaling network, BARD1 signaling events | ||
| Validated targets of C-MYC transcriptional repression, ATM pathway | ||
| CDPathway | Signaling events mediated by VEGFR1 and VEGFR2, FGF signaling pathway, SHP2 signaling | 17 |
| p75 (NTR)-mediated signaling, ErbB1 downstream signaling, PDGFR-|$\beta $| signaling pathway | ||
| Class I PI3K signaling events, Integrins in angiogenesis, CDC42 signaling events | ||
| BCR signaling pathway, FAS (CD95) signaling pathway, Signaling events mediated by PTP1B | ||
| Signaling events mediated by focal adhesion kinase, CXCR4-mediated signaling events | ||
| Fc-|$\epsilon $| receptor I signaling in mast cells, Angiopoietin receptor Tie2-mediated signaling | ||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| Method . | Driver pathways . | Number . |
|---|---|---|
| Dendrix | Atypical NF-|$\kappa $|B pathway, FOXA1 transcription factor network | 8 |
| FOXA2 and FOXA3 transcription factor networks, BMP receptor signaling | ||
| Wnt signaling network, p38 MAPK signaling pathway, Ceramide signaling pathway | ||
| Validated transcriptional targets of |$\delta $|Np63 isoforms | ||
| MDPfinder | Nectin adhesion pathway, ErbB receptor signaling network, mTOR signaling pathway | 8 |
| FOXA2 and FOXA3 transcription factor networks, BARD1 signaling events | ||
| Wnt signaling network, FOXA1 transcription factor network, Regulation of RhoA activity | ||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||
| Multi-Dendrix | Arf1 pathway, p53 pathway, BMP receptor signaling, LKB1 signaling events | 11 |
| ATM pathway, Wnt signaling network, C-MYC pathway, Notch signaling pathway | ||
| IL2 signaling events mediated by STAT5, ErbB receptor signaling network | ||
| FOXA2 and FOXA3 transcription factor networks | ||
| CoMDP | Nectin adhesion pathway, PLK3 signaling events, Wnt signaling network | 11 |
| AP-1 transcription factor network, FOXA1 transcription factor network | ||
| FGF signaling pathway, Atypical NF-|$\kappa $|B pathway, PLK1 signaling events | ||
| ErbB receptor signaling network, IL2 signaling events mediated by STAT5 | ||
| Signaling events mediated by the Hedgehog family | ||
| MCSS | E-cadherin signaling in keratinocytes, N-cadherin signaling events | 12 |
| Canonical NF-|$\kappa $|B pathway, Notch signaling pathway, p53 pathway | ||
| FOXA2 and FOXA3 transcription factor networks, LKB1 signaling events | ||
| C-MYC pathway, Wnt signaling network, BARD1 signaling events | ||
| Validated targets of C-MYC transcriptional repression, ATM pathway | ||
| CDPathway | Signaling events mediated by VEGFR1 and VEGFR2, FGF signaling pathway, SHP2 signaling | 17 |
| p75 (NTR)-mediated signaling, ErbB1 downstream signaling, PDGFR-|$\beta $| signaling pathway | ||
| Class I PI3K signaling events, Integrins in angiogenesis, CDC42 signaling events | ||
| BCR signaling pathway, FAS (CD95) signaling pathway, Signaling events mediated by PTP1B | ||
| Signaling events mediated by focal adhesion kinase, CXCR4-mediated signaling events | ||
| Fc-|$\epsilon $| receptor I signaling in mast cells, Angiopoietin receptor Tie2-mediated signaling | ||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| Method . | Driver pathways . | Number . |
|---|---|---|
| Dendrix | Atypical NF-|$\kappa $|B pathway, FOXA1 transcription factor network | 8 |
| FOXA2 and FOXA3 transcription factor networks, BMP receptor signaling | ||
| Wnt signaling network, p38 MAPK signaling pathway, Ceramide signaling pathway | ||
| Validated transcriptional targets of |$\delta $|Np63 isoforms | ||
| MDPfinder | Nectin adhesion pathway, ErbB receptor signaling network, mTOR signaling pathway | 8 |
| FOXA2 and FOXA3 transcription factor networks, BARD1 signaling events | ||
| Wnt signaling network, FOXA1 transcription factor network, Regulation of RhoA activity | ||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||
| Multi-Dendrix | Arf1 pathway, p53 pathway, BMP receptor signaling, LKB1 signaling events | 11 |
| ATM pathway, Wnt signaling network, C-MYC pathway, Notch signaling pathway | ||
| IL2 signaling events mediated by STAT5, ErbB receptor signaling network | ||
| FOXA2 and FOXA3 transcription factor networks | ||
| CoMDP | Nectin adhesion pathway, PLK3 signaling events, Wnt signaling network | 11 |
| AP-1 transcription factor network, FOXA1 transcription factor network | ||
| FGF signaling pathway, Atypical NF-|$\kappa $|B pathway, PLK1 signaling events | ||
| ErbB receptor signaling network, IL2 signaling events mediated by STAT5 | ||
| Signaling events mediated by the Hedgehog family | ||
| MCSS | E-cadherin signaling in keratinocytes, N-cadherin signaling events | 12 |
| Canonical NF-|$\kappa $|B pathway, Notch signaling pathway, p53 pathway | ||
| FOXA2 and FOXA3 transcription factor networks, LKB1 signaling events | ||
| C-MYC pathway, Wnt signaling network, BARD1 signaling events | ||
| Validated targets of C-MYC transcriptional repression, ATM pathway | ||
| CDPathway | Signaling events mediated by VEGFR1 and VEGFR2, FGF signaling pathway, SHP2 signaling | 17 |
| p75 (NTR)-mediated signaling, ErbB1 downstream signaling, PDGFR-|$\beta $| signaling pathway | ||
| Class I PI3K signaling events, Integrins in angiogenesis, CDC42 signaling events | ||
| BCR signaling pathway, FAS (CD95) signaling pathway, Signaling events mediated by PTP1B | ||
| Signaling events mediated by focal adhesion kinase, CXCR4-mediated signaling events | ||
| Fc-|$\epsilon $| receptor I signaling in mast cells, Angiopoietin receptor Tie2-mediated signaling | ||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| Method . | Driver pathways . | Number . |
|---|---|---|
| Dendrix | Atypical NF-|$\kappa $|B pathway, FOXA1 transcription factor network | 8 |
| FOXA2 and FOXA3 transcription factor networks, BMP receptor signaling | ||
| Wnt signaling network, p38 MAPK signaling pathway, Ceramide signaling pathway | ||
| Validated transcriptional targets of |$\delta $|Np63 isoforms | ||
| MDPfinder | Nectin adhesion pathway, ErbB receptor signaling network, mTOR signaling pathway | 8 |
| FOXA2 and FOXA3 transcription factor networks, BARD1 signaling events | ||
| Wnt signaling network, FOXA1 transcription factor network, Regulation of RhoA activity | ||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||
| Multi-Dendrix | Arf1 pathway, p53 pathway, BMP receptor signaling, LKB1 signaling events | 11 |
| ATM pathway, Wnt signaling network, C-MYC pathway, Notch signaling pathway | ||
| IL2 signaling events mediated by STAT5, ErbB receptor signaling network | ||
| FOXA2 and FOXA3 transcription factor networks | ||
| CoMDP | Nectin adhesion pathway, PLK3 signaling events, Wnt signaling network | 11 |
| AP-1 transcription factor network, FOXA1 transcription factor network | ||
| FGF signaling pathway, Atypical NF-|$\kappa $|B pathway, PLK1 signaling events | ||
| ErbB receptor signaling network, IL2 signaling events mediated by STAT5 | ||
| Signaling events mediated by the Hedgehog family | ||
| MCSS | E-cadherin signaling in keratinocytes, N-cadherin signaling events | 12 |
| Canonical NF-|$\kappa $|B pathway, Notch signaling pathway, p53 pathway | ||
| FOXA2 and FOXA3 transcription factor networks, LKB1 signaling events | ||
| C-MYC pathway, Wnt signaling network, BARD1 signaling events | ||
| Validated targets of C-MYC transcriptional repression, ATM pathway | ||
| CDPathway | Signaling events mediated by VEGFR1 and VEGFR2, FGF signaling pathway, SHP2 signaling | 17 |
| p75 (NTR)-mediated signaling, ErbB1 downstream signaling, PDGFR-|$\beta $| signaling pathway | ||
| Class I PI3K signaling events, Integrins in angiogenesis, CDC42 signaling events | ||
| BCR signaling pathway, FAS (CD95) signaling pathway, Signaling events mediated by PTP1B | ||
| Signaling events mediated by focal adhesion kinase, CXCR4-mediated signaling events | ||
| Fc-|$\epsilon $| receptor I signaling in mast cells, Angiopoietin receptor Tie2-mediated signaling | ||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
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