Table 1.

Demographic and Clinical Characteristics of Children and Young Adults With Sepsis, by Age Group

CharacteristicAge Group
Total (N = 736)30 Days–11 Months (n = 90)1–4 Years (n = 145)5–12 Years (n = 219)13–21 Years (n = 282)
State of residence
 California67 (9.1)6 (6.7)16 (11.0)20 (9.1)25 (8.9)
 Colorado94 (12.8)5 (5.6)18 (12.4)30 (13.7)41 (14.5)
 Connecticut82 (11.1)6 (6.7)14 (9.7)22 (10.0)40 (14.2)
 Georgia105 (14.3)19 (21.1)24 (16.6)34 (15.5)28 (9.9)
 Maryland94 (12.8)13 (14.4)24 (16.6)34 (15.5)23 (8.2)
 Minnesota87 (11.8)20 (22.2)13 (9.0)28 (12.8)26 (9.2)
 New Mexico38 (5.2)5 (5.6)4 (2.8)8 (3.7)21 (7.4)
 New York47 (6.4)7 (7.8)9 (6.2)9 (4.1)22 (7.8)
 Oregon59 (8.0)3 (3.3)13 (9.0)14 (6.4)29 (10.3)
 Tennessee63 (8.6)6 (6.7)10 (6.9)20 (9.1)27 (9.6)
Sex
 Female386 (52.4)48 (53.3)75 (51.7)123 (56.2)140 (49.6)
 Male350 (47.6)42 (46.7)70 (48.3)96 (43.8)142 (50.4)
Race/ethnicitya
 American Indian, non-Hispanic16 (2.2)5 (5.6)2 (1.4)4 (1.8)5 (1.8)
 Asian, non-Hispanic29 (3.9)6 (6.7)4 (2.8)11 (5.0)8 (2.8)
 Black, non-Hispanic129 (17.5)21 (23.3)32 (22.1)33 (15.1)43 (15.2)
 Hispanic/Latino144 (19.6)18 (20.0)25 (17.2)47 (21.5)54 (19.1)
 Pacific Islander, non-Hispanic4 (0.5)1 (1.1)01 (0.5)2 (0.7)
 White, non-Hispanic355 (48.2)34 (37.8)66 (45.5)104 (47.5)151 (53.5)
 Other or multiple races, non-Hispanic29 (3.9)09 (6.2)13 (5.9)7 (2.5)
 Unknown race, non-Hispanic30 (4.1)5 (5.6)7 (4.8)6 (2.7)12 (4.3)
Primary insurance type
 Medicaid416 (56.5)55 (61.1)89 (61.4)128 (58.4)144 (51.1)
 Private254 (34.5)24 (26.7)36 (24.8)74 (33.8)120 (42.6)
 Other47 (6.4)7 (7.8)17 (11.7)11 (5.0)12 (4.3)
 Unknown19 (2.6)4 (4.4)3 (2.1)6 (2.7)6 (2.1)
Location immediately before sepsis admission
 Private residence378 (51.4)44 (48.9)77 (53.1)116 (53.0)141 (50.0)
 Another acute care hospital or emergency department271 (36.8)41 (45.6)46 (31.7)82 (37.4)102 (37.6)
 Outpatient clinic or urgent care73 (9.9)5 (5.6)21 (14.5)20 (9.1)27 (9.6)
 Nursing home4 (0.5)0004 (1.4)
 Other6 (0.8)001 (0.5)5 (1.8)
 Unknown4 (0.5)01 (0.7)03 (1.1)
Location 4 days before sepsis admission
 Private residence676 (91.8)85 (94.4)135 (93.1)200 (91.3)256 (90.8)
 Another acute care hospital38 (5.2)5 (5.6)7 (4.8)13 (5.9)13 (4.6)
 Nursing home5 (0.7)01 (0.7)04 (1.4)
 Otherb11 (1.5)01 (0.7)3 (1.4)7 (2.5)
 Unknown6 (0.8)01 (0.7)3 (1.4)2 (0.7)
Underlying conditions
 Any underlying conditionc442 (60.1)49 (54.4)93 (64.1)132 (60.3)168 (59.6)
 Chronic pulmonary diseased137 (18.6)6 (6.7)33 (22.8)51 (23.3)47 (16.7)
 Chronic cognitive deficit118 (16.0)8 (8.9)31 (21.4)40 (18.3)39 (13.8)
 Chronic immunocompromisee109 (14.8)5 (5.6)17 (11.7)33 (15.1)54 (19.1)
 Hematologic or oncologic disease108 (14.7)3 (3.3)22 (15.2)37 (16.9)46 (16.3)
 History of prematurity90 (12.2)30 (33.3)34 (23.4)14 (6.4)12 (4.3)
 Congenital heart disease63 (8.6)23 (25.6)17 (11.7)10 (4.6)13 (4.6)
 Hemiplegia, paraplegia, quadriplegia42 (5.7)04 (2.8)16 (7.3)22 (7.8)
 Chronic kidney disease31 (4.2)2 (2.2)7 (4.8)10 (4.6)12 (4.3)
 Chronic mental illness18 (2.4)004 (1.8)14 (5.0)
 Other cardiovascular disease17 (2.3)2 (2.2)6 (4.1)5 (2.3)4 (1.4)
 Chronic liver disease15 (2.0)1 (1.1)7 (4.8)2 (0.9)5 (1.8)
 Diabetes mellitusf12 (1.6)01 (0.7)3 (1.4)8 (2.8)
 Chronic wound10 (1.4)2 (2.2)2 (1.4)06 (2.1)
 Connective tissue disease6 (0.8)003 (1.4)3 (1.1)
 Pregnancy2 (0.3)02 (0.7)
 Peptic ulcer disease1 (0.1)0001 (0.4)
 Unknown9 (1.2)1 (1.1)1 (0.7)3 (1.4)4 (1.4)
 Substance useg15 (2.0)015 (5.3)
CharacteristicAge Group
Total (N = 736)30 Days–11 Months (n = 90)1–4 Years (n = 145)5–12 Years (n = 219)13–21 Years (n = 282)
State of residence
 California67 (9.1)6 (6.7)16 (11.0)20 (9.1)25 (8.9)
 Colorado94 (12.8)5 (5.6)18 (12.4)30 (13.7)41 (14.5)
 Connecticut82 (11.1)6 (6.7)14 (9.7)22 (10.0)40 (14.2)
 Georgia105 (14.3)19 (21.1)24 (16.6)34 (15.5)28 (9.9)
 Maryland94 (12.8)13 (14.4)24 (16.6)34 (15.5)23 (8.2)
 Minnesota87 (11.8)20 (22.2)13 (9.0)28 (12.8)26 (9.2)
 New Mexico38 (5.2)5 (5.6)4 (2.8)8 (3.7)21 (7.4)
 New York47 (6.4)7 (7.8)9 (6.2)9 (4.1)22 (7.8)
 Oregon59 (8.0)3 (3.3)13 (9.0)14 (6.4)29 (10.3)
 Tennessee63 (8.6)6 (6.7)10 (6.9)20 (9.1)27 (9.6)
Sex
 Female386 (52.4)48 (53.3)75 (51.7)123 (56.2)140 (49.6)
 Male350 (47.6)42 (46.7)70 (48.3)96 (43.8)142 (50.4)
Race/ethnicitya
 American Indian, non-Hispanic16 (2.2)5 (5.6)2 (1.4)4 (1.8)5 (1.8)
 Asian, non-Hispanic29 (3.9)6 (6.7)4 (2.8)11 (5.0)8 (2.8)
 Black, non-Hispanic129 (17.5)21 (23.3)32 (22.1)33 (15.1)43 (15.2)
 Hispanic/Latino144 (19.6)18 (20.0)25 (17.2)47 (21.5)54 (19.1)
 Pacific Islander, non-Hispanic4 (0.5)1 (1.1)01 (0.5)2 (0.7)
 White, non-Hispanic355 (48.2)34 (37.8)66 (45.5)104 (47.5)151 (53.5)
 Other or multiple races, non-Hispanic29 (3.9)09 (6.2)13 (5.9)7 (2.5)
 Unknown race, non-Hispanic30 (4.1)5 (5.6)7 (4.8)6 (2.7)12 (4.3)
Primary insurance type
 Medicaid416 (56.5)55 (61.1)89 (61.4)128 (58.4)144 (51.1)
 Private254 (34.5)24 (26.7)36 (24.8)74 (33.8)120 (42.6)
 Other47 (6.4)7 (7.8)17 (11.7)11 (5.0)12 (4.3)
 Unknown19 (2.6)4 (4.4)3 (2.1)6 (2.7)6 (2.1)
Location immediately before sepsis admission
 Private residence378 (51.4)44 (48.9)77 (53.1)116 (53.0)141 (50.0)
 Another acute care hospital or emergency department271 (36.8)41 (45.6)46 (31.7)82 (37.4)102 (37.6)
 Outpatient clinic or urgent care73 (9.9)5 (5.6)21 (14.5)20 (9.1)27 (9.6)
 Nursing home4 (0.5)0004 (1.4)
 Other6 (0.8)001 (0.5)5 (1.8)
 Unknown4 (0.5)01 (0.7)03 (1.1)
Location 4 days before sepsis admission
 Private residence676 (91.8)85 (94.4)135 (93.1)200 (91.3)256 (90.8)
 Another acute care hospital38 (5.2)5 (5.6)7 (4.8)13 (5.9)13 (4.6)
 Nursing home5 (0.7)01 (0.7)04 (1.4)
 Otherb11 (1.5)01 (0.7)3 (1.4)7 (2.5)
 Unknown6 (0.8)01 (0.7)3 (1.4)2 (0.7)
Underlying conditions
 Any underlying conditionc442 (60.1)49 (54.4)93 (64.1)132 (60.3)168 (59.6)
 Chronic pulmonary diseased137 (18.6)6 (6.7)33 (22.8)51 (23.3)47 (16.7)
 Chronic cognitive deficit118 (16.0)8 (8.9)31 (21.4)40 (18.3)39 (13.8)
 Chronic immunocompromisee109 (14.8)5 (5.6)17 (11.7)33 (15.1)54 (19.1)
 Hematologic or oncologic disease108 (14.7)3 (3.3)22 (15.2)37 (16.9)46 (16.3)
 History of prematurity90 (12.2)30 (33.3)34 (23.4)14 (6.4)12 (4.3)
 Congenital heart disease63 (8.6)23 (25.6)17 (11.7)10 (4.6)13 (4.6)
 Hemiplegia, paraplegia, quadriplegia42 (5.7)04 (2.8)16 (7.3)22 (7.8)
 Chronic kidney disease31 (4.2)2 (2.2)7 (4.8)10 (4.6)12 (4.3)
 Chronic mental illness18 (2.4)004 (1.8)14 (5.0)
 Other cardiovascular disease17 (2.3)2 (2.2)6 (4.1)5 (2.3)4 (1.4)
 Chronic liver disease15 (2.0)1 (1.1)7 (4.8)2 (0.9)5 (1.8)
 Diabetes mellitusf12 (1.6)01 (0.7)3 (1.4)8 (2.8)
 Chronic wound10 (1.4)2 (2.2)2 (1.4)06 (2.1)
 Connective tissue disease6 (0.8)003 (1.4)3 (1.1)
 Pregnancy2 (0.3)02 (0.7)
 Peptic ulcer disease1 (0.1)0001 (0.4)
 Unknown9 (1.2)1 (1.1)1 (0.7)3 (1.4)4 (1.4)
 Substance useg15 (2.0)015 (5.3)

Data are presented as No. (%).

a

Persons with unknown ethnicity are grouped with persons reported as non-Hispanic.

b

Including persons experiencing homelessness or incarceration.

c

Includes any of the conditions listed.

d

Including asthma in 91 of 137 patients.

e

Defined as asplenia, neutropenia, hematopoietic stem cell transplant, solid organ transplant, human immunodeficiency virus infection, primary immunodeficiency, or chronic steroid or other immunosuppressive therapy.

f

Includes type 1 and type 2 diabetes mellitus and gestational diabetes.

g

Includes alcohol use disorder, injection drug use, and smoking.

Table 1.

Demographic and Clinical Characteristics of Children and Young Adults With Sepsis, by Age Group

CharacteristicAge Group
Total (N = 736)30 Days–11 Months (n = 90)1–4 Years (n = 145)5–12 Years (n = 219)13–21 Years (n = 282)
State of residence
 California67 (9.1)6 (6.7)16 (11.0)20 (9.1)25 (8.9)
 Colorado94 (12.8)5 (5.6)18 (12.4)30 (13.7)41 (14.5)
 Connecticut82 (11.1)6 (6.7)14 (9.7)22 (10.0)40 (14.2)
 Georgia105 (14.3)19 (21.1)24 (16.6)34 (15.5)28 (9.9)
 Maryland94 (12.8)13 (14.4)24 (16.6)34 (15.5)23 (8.2)
 Minnesota87 (11.8)20 (22.2)13 (9.0)28 (12.8)26 (9.2)
 New Mexico38 (5.2)5 (5.6)4 (2.8)8 (3.7)21 (7.4)
 New York47 (6.4)7 (7.8)9 (6.2)9 (4.1)22 (7.8)
 Oregon59 (8.0)3 (3.3)13 (9.0)14 (6.4)29 (10.3)
 Tennessee63 (8.6)6 (6.7)10 (6.9)20 (9.1)27 (9.6)
Sex
 Female386 (52.4)48 (53.3)75 (51.7)123 (56.2)140 (49.6)
 Male350 (47.6)42 (46.7)70 (48.3)96 (43.8)142 (50.4)
Race/ethnicitya
 American Indian, non-Hispanic16 (2.2)5 (5.6)2 (1.4)4 (1.8)5 (1.8)
 Asian, non-Hispanic29 (3.9)6 (6.7)4 (2.8)11 (5.0)8 (2.8)
 Black, non-Hispanic129 (17.5)21 (23.3)32 (22.1)33 (15.1)43 (15.2)
 Hispanic/Latino144 (19.6)18 (20.0)25 (17.2)47 (21.5)54 (19.1)
 Pacific Islander, non-Hispanic4 (0.5)1 (1.1)01 (0.5)2 (0.7)
 White, non-Hispanic355 (48.2)34 (37.8)66 (45.5)104 (47.5)151 (53.5)
 Other or multiple races, non-Hispanic29 (3.9)09 (6.2)13 (5.9)7 (2.5)
 Unknown race, non-Hispanic30 (4.1)5 (5.6)7 (4.8)6 (2.7)12 (4.3)
Primary insurance type
 Medicaid416 (56.5)55 (61.1)89 (61.4)128 (58.4)144 (51.1)
 Private254 (34.5)24 (26.7)36 (24.8)74 (33.8)120 (42.6)
 Other47 (6.4)7 (7.8)17 (11.7)11 (5.0)12 (4.3)
 Unknown19 (2.6)4 (4.4)3 (2.1)6 (2.7)6 (2.1)
Location immediately before sepsis admission
 Private residence378 (51.4)44 (48.9)77 (53.1)116 (53.0)141 (50.0)
 Another acute care hospital or emergency department271 (36.8)41 (45.6)46 (31.7)82 (37.4)102 (37.6)
 Outpatient clinic or urgent care73 (9.9)5 (5.6)21 (14.5)20 (9.1)27 (9.6)
 Nursing home4 (0.5)0004 (1.4)
 Other6 (0.8)001 (0.5)5 (1.8)
 Unknown4 (0.5)01 (0.7)03 (1.1)
Location 4 days before sepsis admission
 Private residence676 (91.8)85 (94.4)135 (93.1)200 (91.3)256 (90.8)
 Another acute care hospital38 (5.2)5 (5.6)7 (4.8)13 (5.9)13 (4.6)
 Nursing home5 (0.7)01 (0.7)04 (1.4)
 Otherb11 (1.5)01 (0.7)3 (1.4)7 (2.5)
 Unknown6 (0.8)01 (0.7)3 (1.4)2 (0.7)
Underlying conditions
 Any underlying conditionc442 (60.1)49 (54.4)93 (64.1)132 (60.3)168 (59.6)
 Chronic pulmonary diseased137 (18.6)6 (6.7)33 (22.8)51 (23.3)47 (16.7)
 Chronic cognitive deficit118 (16.0)8 (8.9)31 (21.4)40 (18.3)39 (13.8)
 Chronic immunocompromisee109 (14.8)5 (5.6)17 (11.7)33 (15.1)54 (19.1)
 Hematologic or oncologic disease108 (14.7)3 (3.3)22 (15.2)37 (16.9)46 (16.3)
 History of prematurity90 (12.2)30 (33.3)34 (23.4)14 (6.4)12 (4.3)
 Congenital heart disease63 (8.6)23 (25.6)17 (11.7)10 (4.6)13 (4.6)
 Hemiplegia, paraplegia, quadriplegia42 (5.7)04 (2.8)16 (7.3)22 (7.8)
 Chronic kidney disease31 (4.2)2 (2.2)7 (4.8)10 (4.6)12 (4.3)
 Chronic mental illness18 (2.4)004 (1.8)14 (5.0)
 Other cardiovascular disease17 (2.3)2 (2.2)6 (4.1)5 (2.3)4 (1.4)
 Chronic liver disease15 (2.0)1 (1.1)7 (4.8)2 (0.9)5 (1.8)
 Diabetes mellitusf12 (1.6)01 (0.7)3 (1.4)8 (2.8)
 Chronic wound10 (1.4)2 (2.2)2 (1.4)06 (2.1)
 Connective tissue disease6 (0.8)003 (1.4)3 (1.1)
 Pregnancy2 (0.3)02 (0.7)
 Peptic ulcer disease1 (0.1)0001 (0.4)
 Unknown9 (1.2)1 (1.1)1 (0.7)3 (1.4)4 (1.4)
 Substance useg15 (2.0)015 (5.3)
CharacteristicAge Group
Total (N = 736)30 Days–11 Months (n = 90)1–4 Years (n = 145)5–12 Years (n = 219)13–21 Years (n = 282)
State of residence
 California67 (9.1)6 (6.7)16 (11.0)20 (9.1)25 (8.9)
 Colorado94 (12.8)5 (5.6)18 (12.4)30 (13.7)41 (14.5)
 Connecticut82 (11.1)6 (6.7)14 (9.7)22 (10.0)40 (14.2)
 Georgia105 (14.3)19 (21.1)24 (16.6)34 (15.5)28 (9.9)
 Maryland94 (12.8)13 (14.4)24 (16.6)34 (15.5)23 (8.2)
 Minnesota87 (11.8)20 (22.2)13 (9.0)28 (12.8)26 (9.2)
 New Mexico38 (5.2)5 (5.6)4 (2.8)8 (3.7)21 (7.4)
 New York47 (6.4)7 (7.8)9 (6.2)9 (4.1)22 (7.8)
 Oregon59 (8.0)3 (3.3)13 (9.0)14 (6.4)29 (10.3)
 Tennessee63 (8.6)6 (6.7)10 (6.9)20 (9.1)27 (9.6)
Sex
 Female386 (52.4)48 (53.3)75 (51.7)123 (56.2)140 (49.6)
 Male350 (47.6)42 (46.7)70 (48.3)96 (43.8)142 (50.4)
Race/ethnicitya
 American Indian, non-Hispanic16 (2.2)5 (5.6)2 (1.4)4 (1.8)5 (1.8)
 Asian, non-Hispanic29 (3.9)6 (6.7)4 (2.8)11 (5.0)8 (2.8)
 Black, non-Hispanic129 (17.5)21 (23.3)32 (22.1)33 (15.1)43 (15.2)
 Hispanic/Latino144 (19.6)18 (20.0)25 (17.2)47 (21.5)54 (19.1)
 Pacific Islander, non-Hispanic4 (0.5)1 (1.1)01 (0.5)2 (0.7)
 White, non-Hispanic355 (48.2)34 (37.8)66 (45.5)104 (47.5)151 (53.5)
 Other or multiple races, non-Hispanic29 (3.9)09 (6.2)13 (5.9)7 (2.5)
 Unknown race, non-Hispanic30 (4.1)5 (5.6)7 (4.8)6 (2.7)12 (4.3)
Primary insurance type
 Medicaid416 (56.5)55 (61.1)89 (61.4)128 (58.4)144 (51.1)
 Private254 (34.5)24 (26.7)36 (24.8)74 (33.8)120 (42.6)
 Other47 (6.4)7 (7.8)17 (11.7)11 (5.0)12 (4.3)
 Unknown19 (2.6)4 (4.4)3 (2.1)6 (2.7)6 (2.1)
Location immediately before sepsis admission
 Private residence378 (51.4)44 (48.9)77 (53.1)116 (53.0)141 (50.0)
 Another acute care hospital or emergency department271 (36.8)41 (45.6)46 (31.7)82 (37.4)102 (37.6)
 Outpatient clinic or urgent care73 (9.9)5 (5.6)21 (14.5)20 (9.1)27 (9.6)
 Nursing home4 (0.5)0004 (1.4)
 Other6 (0.8)001 (0.5)5 (1.8)
 Unknown4 (0.5)01 (0.7)03 (1.1)
Location 4 days before sepsis admission
 Private residence676 (91.8)85 (94.4)135 (93.1)200 (91.3)256 (90.8)
 Another acute care hospital38 (5.2)5 (5.6)7 (4.8)13 (5.9)13 (4.6)
 Nursing home5 (0.7)01 (0.7)04 (1.4)
 Otherb11 (1.5)01 (0.7)3 (1.4)7 (2.5)
 Unknown6 (0.8)01 (0.7)3 (1.4)2 (0.7)
Underlying conditions
 Any underlying conditionc442 (60.1)49 (54.4)93 (64.1)132 (60.3)168 (59.6)
 Chronic pulmonary diseased137 (18.6)6 (6.7)33 (22.8)51 (23.3)47 (16.7)
 Chronic cognitive deficit118 (16.0)8 (8.9)31 (21.4)40 (18.3)39 (13.8)
 Chronic immunocompromisee109 (14.8)5 (5.6)17 (11.7)33 (15.1)54 (19.1)
 Hematologic or oncologic disease108 (14.7)3 (3.3)22 (15.2)37 (16.9)46 (16.3)
 History of prematurity90 (12.2)30 (33.3)34 (23.4)14 (6.4)12 (4.3)
 Congenital heart disease63 (8.6)23 (25.6)17 (11.7)10 (4.6)13 (4.6)
 Hemiplegia, paraplegia, quadriplegia42 (5.7)04 (2.8)16 (7.3)22 (7.8)
 Chronic kidney disease31 (4.2)2 (2.2)7 (4.8)10 (4.6)12 (4.3)
 Chronic mental illness18 (2.4)004 (1.8)14 (5.0)
 Other cardiovascular disease17 (2.3)2 (2.2)6 (4.1)5 (2.3)4 (1.4)
 Chronic liver disease15 (2.0)1 (1.1)7 (4.8)2 (0.9)5 (1.8)
 Diabetes mellitusf12 (1.6)01 (0.7)3 (1.4)8 (2.8)
 Chronic wound10 (1.4)2 (2.2)2 (1.4)06 (2.1)
 Connective tissue disease6 (0.8)003 (1.4)3 (1.1)
 Pregnancy2 (0.3)02 (0.7)
 Peptic ulcer disease1 (0.1)0001 (0.4)
 Unknown9 (1.2)1 (1.1)1 (0.7)3 (1.4)4 (1.4)
 Substance useg15 (2.0)015 (5.3)

Data are presented as No. (%).

a

Persons with unknown ethnicity are grouped with persons reported as non-Hispanic.

b

Including persons experiencing homelessness or incarceration.

c

Includes any of the conditions listed.

d

Including asthma in 91 of 137 patients.

e

Defined as asplenia, neutropenia, hematopoietic stem cell transplant, solid organ transplant, human immunodeficiency virus infection, primary immunodeficiency, or chronic steroid or other immunosuppressive therapy.

f

Includes type 1 and type 2 diabetes mellitus and gestational diabetes.

g

Includes alcohol use disorder, injection drug use, and smoking.

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