| Parameter . | Maximal septal thickness ≤19 mm (N = 64) . | Maximal septal thickness ≥20 mm (N = 161)* . | P-value for interaction . | ||||
|---|---|---|---|---|---|---|---|
| . | Before surgery . | After surgery . | P-value . | Before surgery . | After surgery . | P-value . | . |
| NYHA functional class | |||||||
| ȃI | 0 | 56 (87%) | <0.001 | 0 | 132 (82%) | <0.001 | 0.202 |
| ȃII | 10 (16%) | ȃ8 (13%) | ȃ38 (24%) | ȃ27 (17%) | |||
| ȃIII | 50 (78%) | 0 | 106 (66%) | ȃ2 (1%) | |||
| ȃIV | 4 (6%) | 0 | ȃ17 (11%) | 0 | |||
| Atrial fibrillation | |||||||
| ȃNo | 49 (77%) | 59 (92%) | 0.004 | 133 (83%) | 151 (94%) | <0.001 | 0.812 |
| ȃYes | 15 (23%) | 5 (8%) | ȃ28 (17%) | 10 (6%) | |||
| Ecocardiographic data | |||||||
| LVOT gradient at rest, mmHg | 71 ± 41 | 11 ± 5 | <0.001 | 69 ± 34 | 11 ± 6 | <0.001 | 0.813 |
| Septal thickness, mm | 18 ± 2 | 14 ± 2 | <0.001 | 25 ± 4 | 17 ± 4 | <0.001 | <0.001 |
| Post-op gradient at rest ≥30 mmHg | |||||||
| ȃNo | ȃNA | ȃ64 (100%) | NA | ȃNA | ȃ158 (98%) | NA | NA |
| ȃYes | ȃNA | 0 | ȃNA | ȃ3 (2%) | |||
| LV ejection fraction, % | 67 ± 6 | 63 ± 6 | <0.001 | 65 ± 6 | 63 ± 6 | 0.003 | 0.135 |
| LV end systolic volume, mL | ȃ28 ± 11 | 33 ± 12 | 0.003 | 33 ± 14 | 38 ± 15 | <0.001 | 0.627 |
| LV end diastolic volume, mL | ȃ88 ± 29 | 89 ± 23 | 0.860 | 95 ± 30 | 102 ± 29 | 0.013 | 0.224 |
| MV regurgitation | |||||||
| ȃ0–1 | 20 (31%) | 55 (86%) | <0.001 | 44 (27%) | 139 (86%) | <0.001 | 0.911 |
| ȃ2 | 25 (39%) | ȃ8 (13%) | 71 (44%) | ȃ19 (12%) | |||
| ȃ3 | ȃ8 (13%) | 1 (2%) | 26 (16%) | ȃ3 (2%) | |||
| ȃ4 | 11 (17%) | ȃ0 | 20 (12%) | ȃ0 | |||
| Parameter . | Maximal septal thickness ≤19 mm (N = 64) . | Maximal septal thickness ≥20 mm (N = 161)* . | P-value for interaction . | ||||
|---|---|---|---|---|---|---|---|
| . | Before surgery . | After surgery . | P-value . | Before surgery . | After surgery . | P-value . | . |
| NYHA functional class | |||||||
| ȃI | 0 | 56 (87%) | <0.001 | 0 | 132 (82%) | <0.001 | 0.202 |
| ȃII | 10 (16%) | ȃ8 (13%) | ȃ38 (24%) | ȃ27 (17%) | |||
| ȃIII | 50 (78%) | 0 | 106 (66%) | ȃ2 (1%) | |||
| ȃIV | 4 (6%) | 0 | ȃ17 (11%) | 0 | |||
| Atrial fibrillation | |||||||
| ȃNo | 49 (77%) | 59 (92%) | 0.004 | 133 (83%) | 151 (94%) | <0.001 | 0.812 |
| ȃYes | 15 (23%) | 5 (8%) | ȃ28 (17%) | 10 (6%) | |||
| Ecocardiographic data | |||||||
| LVOT gradient at rest, mmHg | 71 ± 41 | 11 ± 5 | <0.001 | 69 ± 34 | 11 ± 6 | <0.001 | 0.813 |
| Septal thickness, mm | 18 ± 2 | 14 ± 2 | <0.001 | 25 ± 4 | 17 ± 4 | <0.001 | <0.001 |
| Post-op gradient at rest ≥30 mmHg | |||||||
| ȃNo | ȃNA | ȃ64 (100%) | NA | ȃNA | ȃ158 (98%) | NA | NA |
| ȃYes | ȃNA | 0 | ȃNA | ȃ3 (2%) | |||
| LV ejection fraction, % | 67 ± 6 | 63 ± 6 | <0.001 | 65 ± 6 | 63 ± 6 | 0.003 | 0.135 |
| LV end systolic volume, mL | ȃ28 ± 11 | 33 ± 12 | 0.003 | 33 ± 14 | 38 ± 15 | <0.001 | 0.627 |
| LV end diastolic volume, mL | ȃ88 ± 29 | 89 ± 23 | 0.860 | 95 ± 30 | 102 ± 29 | 0.013 | 0.224 |
| MV regurgitation | |||||||
| ȃ0–1 | 20 (31%) | 55 (86%) | <0.001 | 44 (27%) | 139 (86%) | <0.001 | 0.911 |
| ȃ2 | 25 (39%) | ȃ8 (13%) | 71 (44%) | ȃ19 (12%) | |||
| ȃ3 | ȃ8 (13%) | 1 (2%) | 26 (16%) | ȃ3 (2%) | |||
| ȃ4 | 11 (17%) | ȃ0 | 20 (12%) | ȃ0 | |||
LV = left ventricle; LVOT = left ventricular outflow tract; MV = mitral valve; NA = not applicable; NYHA = New York Heart Association.
Symbols: *One of the 226 study patients died postoperatively during hospitalization.
| Parameter . | Maximal septal thickness ≤19 mm (N = 64) . | Maximal septal thickness ≥20 mm (N = 161)* . | P-value for interaction . | ||||
|---|---|---|---|---|---|---|---|
| . | Before surgery . | After surgery . | P-value . | Before surgery . | After surgery . | P-value . | . |
| NYHA functional class | |||||||
| ȃI | 0 | 56 (87%) | <0.001 | 0 | 132 (82%) | <0.001 | 0.202 |
| ȃII | 10 (16%) | ȃ8 (13%) | ȃ38 (24%) | ȃ27 (17%) | |||
| ȃIII | 50 (78%) | 0 | 106 (66%) | ȃ2 (1%) | |||
| ȃIV | 4 (6%) | 0 | ȃ17 (11%) | 0 | |||
| Atrial fibrillation | |||||||
| ȃNo | 49 (77%) | 59 (92%) | 0.004 | 133 (83%) | 151 (94%) | <0.001 | 0.812 |
| ȃYes | 15 (23%) | 5 (8%) | ȃ28 (17%) | 10 (6%) | |||
| Ecocardiographic data | |||||||
| LVOT gradient at rest, mmHg | 71 ± 41 | 11 ± 5 | <0.001 | 69 ± 34 | 11 ± 6 | <0.001 | 0.813 |
| Septal thickness, mm | 18 ± 2 | 14 ± 2 | <0.001 | 25 ± 4 | 17 ± 4 | <0.001 | <0.001 |
| Post-op gradient at rest ≥30 mmHg | |||||||
| ȃNo | ȃNA | ȃ64 (100%) | NA | ȃNA | ȃ158 (98%) | NA | NA |
| ȃYes | ȃNA | 0 | ȃNA | ȃ3 (2%) | |||
| LV ejection fraction, % | 67 ± 6 | 63 ± 6 | <0.001 | 65 ± 6 | 63 ± 6 | 0.003 | 0.135 |
| LV end systolic volume, mL | ȃ28 ± 11 | 33 ± 12 | 0.003 | 33 ± 14 | 38 ± 15 | <0.001 | 0.627 |
| LV end diastolic volume, mL | ȃ88 ± 29 | 89 ± 23 | 0.860 | 95 ± 30 | 102 ± 29 | 0.013 | 0.224 |
| MV regurgitation | |||||||
| ȃ0–1 | 20 (31%) | 55 (86%) | <0.001 | 44 (27%) | 139 (86%) | <0.001 | 0.911 |
| ȃ2 | 25 (39%) | ȃ8 (13%) | 71 (44%) | ȃ19 (12%) | |||
| ȃ3 | ȃ8 (13%) | 1 (2%) | 26 (16%) | ȃ3 (2%) | |||
| ȃ4 | 11 (17%) | ȃ0 | 20 (12%) | ȃ0 | |||
| Parameter . | Maximal septal thickness ≤19 mm (N = 64) . | Maximal septal thickness ≥20 mm (N = 161)* . | P-value for interaction . | ||||
|---|---|---|---|---|---|---|---|
| . | Before surgery . | After surgery . | P-value . | Before surgery . | After surgery . | P-value . | . |
| NYHA functional class | |||||||
| ȃI | 0 | 56 (87%) | <0.001 | 0 | 132 (82%) | <0.001 | 0.202 |
| ȃII | 10 (16%) | ȃ8 (13%) | ȃ38 (24%) | ȃ27 (17%) | |||
| ȃIII | 50 (78%) | 0 | 106 (66%) | ȃ2 (1%) | |||
| ȃIV | 4 (6%) | 0 | ȃ17 (11%) | 0 | |||
| Atrial fibrillation | |||||||
| ȃNo | 49 (77%) | 59 (92%) | 0.004 | 133 (83%) | 151 (94%) | <0.001 | 0.812 |
| ȃYes | 15 (23%) | 5 (8%) | ȃ28 (17%) | 10 (6%) | |||
| Ecocardiographic data | |||||||
| LVOT gradient at rest, mmHg | 71 ± 41 | 11 ± 5 | <0.001 | 69 ± 34 | 11 ± 6 | <0.001 | 0.813 |
| Septal thickness, mm | 18 ± 2 | 14 ± 2 | <0.001 | 25 ± 4 | 17 ± 4 | <0.001 | <0.001 |
| Post-op gradient at rest ≥30 mmHg | |||||||
| ȃNo | ȃNA | ȃ64 (100%) | NA | ȃNA | ȃ158 (98%) | NA | NA |
| ȃYes | ȃNA | 0 | ȃNA | ȃ3 (2%) | |||
| LV ejection fraction, % | 67 ± 6 | 63 ± 6 | <0.001 | 65 ± 6 | 63 ± 6 | 0.003 | 0.135 |
| LV end systolic volume, mL | ȃ28 ± 11 | 33 ± 12 | 0.003 | 33 ± 14 | 38 ± 15 | <0.001 | 0.627 |
| LV end diastolic volume, mL | ȃ88 ± 29 | 89 ± 23 | 0.860 | 95 ± 30 | 102 ± 29 | 0.013 | 0.224 |
| MV regurgitation | |||||||
| ȃ0–1 | 20 (31%) | 55 (86%) | <0.001 | 44 (27%) | 139 (86%) | <0.001 | 0.911 |
| ȃ2 | 25 (39%) | ȃ8 (13%) | 71 (44%) | ȃ19 (12%) | |||
| ȃ3 | ȃ8 (13%) | 1 (2%) | 26 (16%) | ȃ3 (2%) | |||
| ȃ4 | 11 (17%) | ȃ0 | 20 (12%) | ȃ0 | |||
LV = left ventricle; LVOT = left ventricular outflow tract; MV = mitral valve; NA = not applicable; NYHA = New York Heart Association.
Symbols: *One of the 226 study patients died postoperatively during hospitalization.
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