| . | Controls (n = 121) . | HFpEF (n = 134) . | P-value . |
|---|---|---|---|
| Peak watts (W) | 60 (60–80) | 40 (40–60) | < 0.0001 |
| Exercise time (min) | 10.8 ± 3.5 | 8.1 ± 3.3 | < 0.0001 |
| Heart rate (b.p.m.) | 116 ± 21 | 108 ± 23 | 0.008 |
| Systolic BP (mmHg) | 168 ± 30 | 159 ± 32 | 0.03 |
| Diastolic BP (mmHg) | 86 ± 19 | 84 ± 19 | 0.27 |
| Saturation (%) | 95 ± 3 | 95 ± 3 | 0.87 |
| Left heart | |||
| LV ejection fraction (%) | 71 ± 8 | 69 ± 9 | 0.02 |
| E-wave (cm/s) | 116 ± 22 | 127 ± 31 | 0.002 |
| A-wave (cm/s) | 106 ± 30 | 117 ± 37 | 0.03 |
| Mitral e′ (cm/s) | 10.4 ± 2.7 | 7.8 ± 1.9 | < 0.0001 |
| Mitral s′ (cm/s) | 8.9 ± 2.0 | 7.3 ± 1.9 | < 0.0001 |
| E/e′ ratio | 11.4 ± 2.9 | 17.1 ± 6.2 | < 0.0001 |
| Right heart | |||
| TAPSE (mm) | 23.0 ± 5.4 | 19.8 ± 5.1 | <0.0001 |
| TV s′ (cm/s) | 15.0 ± 3.0 | 13.0 ± 3.6 | <0.0001 |
| PASP (mmHg) | 38 ± 10 | 43 ± 13 | 0.0002 |
| TAPSE/PASP | 0.59 (0.48–0.76) | 0.44 (0.34–0.58) | <0.0001 |
| RAP (mmHg) | 5 ± 3 | 7 ± 4 | <0.0001 |
| . | Controls (n = 121) . | HFpEF (n = 134) . | P-value . |
|---|---|---|---|
| Peak watts (W) | 60 (60–80) | 40 (40–60) | < 0.0001 |
| Exercise time (min) | 10.8 ± 3.5 | 8.1 ± 3.3 | < 0.0001 |
| Heart rate (b.p.m.) | 116 ± 21 | 108 ± 23 | 0.008 |
| Systolic BP (mmHg) | 168 ± 30 | 159 ± 32 | 0.03 |
| Diastolic BP (mmHg) | 86 ± 19 | 84 ± 19 | 0.27 |
| Saturation (%) | 95 ± 3 | 95 ± 3 | 0.87 |
| Left heart | |||
| LV ejection fraction (%) | 71 ± 8 | 69 ± 9 | 0.02 |
| E-wave (cm/s) | 116 ± 22 | 127 ± 31 | 0.002 |
| A-wave (cm/s) | 106 ± 30 | 117 ± 37 | 0.03 |
| Mitral e′ (cm/s) | 10.4 ± 2.7 | 7.8 ± 1.9 | < 0.0001 |
| Mitral s′ (cm/s) | 8.9 ± 2.0 | 7.3 ± 1.9 | < 0.0001 |
| E/e′ ratio | 11.4 ± 2.9 | 17.1 ± 6.2 | < 0.0001 |
| Right heart | |||
| TAPSE (mm) | 23.0 ± 5.4 | 19.8 ± 5.1 | <0.0001 |
| TV s′ (cm/s) | 15.0 ± 3.0 | 13.0 ± 3.6 | <0.0001 |
| PASP (mmHg) | 38 ± 10 | 43 ± 13 | 0.0002 |
| TAPSE/PASP | 0.59 (0.48–0.76) | 0.44 (0.34–0.58) | <0.0001 |
| RAP (mmHg) | 5 ± 3 | 7 ± 4 | <0.0001 |
Data are given as mean ± SD or median (interquartile range). Abbreviations as in Table 2.
| . | Controls (n = 121) . | HFpEF (n = 134) . | P-value . |
|---|---|---|---|
| Peak watts (W) | 60 (60–80) | 40 (40–60) | < 0.0001 |
| Exercise time (min) | 10.8 ± 3.5 | 8.1 ± 3.3 | < 0.0001 |
| Heart rate (b.p.m.) | 116 ± 21 | 108 ± 23 | 0.008 |
| Systolic BP (mmHg) | 168 ± 30 | 159 ± 32 | 0.03 |
| Diastolic BP (mmHg) | 86 ± 19 | 84 ± 19 | 0.27 |
| Saturation (%) | 95 ± 3 | 95 ± 3 | 0.87 |
| Left heart | |||
| LV ejection fraction (%) | 71 ± 8 | 69 ± 9 | 0.02 |
| E-wave (cm/s) | 116 ± 22 | 127 ± 31 | 0.002 |
| A-wave (cm/s) | 106 ± 30 | 117 ± 37 | 0.03 |
| Mitral e′ (cm/s) | 10.4 ± 2.7 | 7.8 ± 1.9 | < 0.0001 |
| Mitral s′ (cm/s) | 8.9 ± 2.0 | 7.3 ± 1.9 | < 0.0001 |
| E/e′ ratio | 11.4 ± 2.9 | 17.1 ± 6.2 | < 0.0001 |
| Right heart | |||
| TAPSE (mm) | 23.0 ± 5.4 | 19.8 ± 5.1 | <0.0001 |
| TV s′ (cm/s) | 15.0 ± 3.0 | 13.0 ± 3.6 | <0.0001 |
| PASP (mmHg) | 38 ± 10 | 43 ± 13 | 0.0002 |
| TAPSE/PASP | 0.59 (0.48–0.76) | 0.44 (0.34–0.58) | <0.0001 |
| RAP (mmHg) | 5 ± 3 | 7 ± 4 | <0.0001 |
| . | Controls (n = 121) . | HFpEF (n = 134) . | P-value . |
|---|---|---|---|
| Peak watts (W) | 60 (60–80) | 40 (40–60) | < 0.0001 |
| Exercise time (min) | 10.8 ± 3.5 | 8.1 ± 3.3 | < 0.0001 |
| Heart rate (b.p.m.) | 116 ± 21 | 108 ± 23 | 0.008 |
| Systolic BP (mmHg) | 168 ± 30 | 159 ± 32 | 0.03 |
| Diastolic BP (mmHg) | 86 ± 19 | 84 ± 19 | 0.27 |
| Saturation (%) | 95 ± 3 | 95 ± 3 | 0.87 |
| Left heart | |||
| LV ejection fraction (%) | 71 ± 8 | 69 ± 9 | 0.02 |
| E-wave (cm/s) | 116 ± 22 | 127 ± 31 | 0.002 |
| A-wave (cm/s) | 106 ± 30 | 117 ± 37 | 0.03 |
| Mitral e′ (cm/s) | 10.4 ± 2.7 | 7.8 ± 1.9 | < 0.0001 |
| Mitral s′ (cm/s) | 8.9 ± 2.0 | 7.3 ± 1.9 | < 0.0001 |
| E/e′ ratio | 11.4 ± 2.9 | 17.1 ± 6.2 | < 0.0001 |
| Right heart | |||
| TAPSE (mm) | 23.0 ± 5.4 | 19.8 ± 5.1 | <0.0001 |
| TV s′ (cm/s) | 15.0 ± 3.0 | 13.0 ± 3.6 | <0.0001 |
| PASP (mmHg) | 38 ± 10 | 43 ± 13 | 0.0002 |
| TAPSE/PASP | 0.59 (0.48–0.76) | 0.44 (0.34–0.58) | <0.0001 |
| RAP (mmHg) | 5 ± 3 | 7 ± 4 | <0.0001 |
Data are given as mean ± SD or median (interquartile range). Abbreviations as in Table 2.
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