Table 2.
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Differentially Expressed Genes: List of Most Stable Differentially Expressed Genes between “Stiff” and “Soft” Biopsies after Patient-wise Leave-one-out Validation

ENTREZ IDGene IDAssociationGene Name
84935MEDAG“Stiff”Mesenteric estrogen dependent Adipogenesis
1378CR1“Stiff”Complement C3b/C4b receptor 1 (Knops blood group)
23213SULF1“Stiff”Sulfatase 1
3875KRT18“Stiff”Keratin 18
9332CD163“Stiff”CD163 molecule
100628315DNM3OS“Stiff”DNM3 opposite strand/antisense RNA
728264CARMN“Stiff”Cardiac mesoderm enhancer-associated noncoding RNA
5325PLAGL1“Stiff”PLAG1 like zinc finger 1
8829NRP1“Stiff”Neuropilin 1
54885TBC1D8B“Stiff”TBC1 domain family member 8B
7373COL14A1“Stiff”Collagen type XIV alpha 1 chain
1282COL4A1“Stiff”Collagen type IV alpha 1 chain
79839CCDC102B“Stiff”Coiled-coil domain containing 102B
1601DAB2“Stiff”DAB adaptor protein 2
3672ITGA1“Stiff”Integrin subunit alpha 1
4121MAN1A1“Stiff”Mannosidase alpha class 1A member 1
55075UACA“Stiff”Uveal autoantigen with coiled-coil domains and ankyrin repeats
5205ATP8B1“Stiff”ATPase phospholipid transporting 8B1
5139PDE3A“Stiff”Phosphodiesterase 3A
22925PLA2R1“Stiff”Phospholipase A2 receptor 1
5592PRKG1“Stiff”Protein kinase cGMP-dependent 1
1909EDNRA“Stiff”Endothelin receptor type A
1290COL5A2“Stiff”Collagen type V alpha 2 chain
1368CPM“Stiff”Carboxypeptidase M
9060PAPSS2“Stiff”3ʹ-phosphoadenosine 5’-phosphosulfate synthase 2
10351ABCA8“Stiff”ATP binding cassette subfamily A member 8
8654PDE5A“Stiff”Phosphodiesterase 5A
3759KCNJ2“Stiff”Potassium inwardly rectifying channel subfamily J member 2
5175PECAM1“Stiff”Platelet and endothelial cell adhesion molEcule 1
2321FLT1“Stiff”Fms related receptor tyrosine kinase 1
115548FCHO2“Stiff”FCH and mu domain containing endocytic adaptor 2
84910TMEM87B“Stiff”Transmembrane protein 87B
9169SCAF11“Stiff”SR-related CTD associated factor 11
23216TBC1D1“Stiff”TBC1 domain family member 1
2803GOLGA4“Stiff”Golgin A4
875CBS“Soft”Cystathionine beta-synthase
728875LINC00623“Soft”Long intergenic non-protein coding RNA 623
93145OLFM2“Soft”Olfactomedin 2
1600DAB1“Soft”DAB adaptor protein 1
767CA8“Soft”Carbonic anhydrase 8
441381LRRC24“Soft”Leucine rich repeat containing 24
81551STMN4“Soft”Stathmin 4
345630FBLL1“Soft”Fibrillarin like 1
ENTREZ IDGene IDAssociationGene Name
84935MEDAG“Stiff”Mesenteric estrogen dependent Adipogenesis
1378CR1“Stiff”Complement C3b/C4b receptor 1 (Knops blood group)
23213SULF1“Stiff”Sulfatase 1
3875KRT18“Stiff”Keratin 18
9332CD163“Stiff”CD163 molecule
100628315DNM3OS“Stiff”DNM3 opposite strand/antisense RNA
728264CARMN“Stiff”Cardiac mesoderm enhancer-associated noncoding RNA
5325PLAGL1“Stiff”PLAG1 like zinc finger 1
8829NRP1“Stiff”Neuropilin 1
54885TBC1D8B“Stiff”TBC1 domain family member 8B
7373COL14A1“Stiff”Collagen type XIV alpha 1 chain
1282COL4A1“Stiff”Collagen type IV alpha 1 chain
79839CCDC102B“Stiff”Coiled-coil domain containing 102B
1601DAB2“Stiff”DAB adaptor protein 2
3672ITGA1“Stiff”Integrin subunit alpha 1
4121MAN1A1“Stiff”Mannosidase alpha class 1A member 1
55075UACA“Stiff”Uveal autoantigen with coiled-coil domains and ankyrin repeats
5205ATP8B1“Stiff”ATPase phospholipid transporting 8B1
5139PDE3A“Stiff”Phosphodiesterase 3A
22925PLA2R1“Stiff”Phospholipase A2 receptor 1
5592PRKG1“Stiff”Protein kinase cGMP-dependent 1
1909EDNRA“Stiff”Endothelin receptor type A
1290COL5A2“Stiff”Collagen type V alpha 2 chain
1368CPM“Stiff”Carboxypeptidase M
9060PAPSS2“Stiff”3ʹ-phosphoadenosine 5’-phosphosulfate synthase 2
10351ABCA8“Stiff”ATP binding cassette subfamily A member 8
8654PDE5A“Stiff”Phosphodiesterase 5A
3759KCNJ2“Stiff”Potassium inwardly rectifying channel subfamily J member 2
5175PECAM1“Stiff”Platelet and endothelial cell adhesion molEcule 1
2321FLT1“Stiff”Fms related receptor tyrosine kinase 1
115548FCHO2“Stiff”FCH and mu domain containing endocytic adaptor 2
84910TMEM87B“Stiff”Transmembrane protein 87B
9169SCAF11“Stiff”SR-related CTD associated factor 11
23216TBC1D1“Stiff”TBC1 domain family member 1
2803GOLGA4“Stiff”Golgin A4
875CBS“Soft”Cystathionine beta-synthase
728875LINC00623“Soft”Long intergenic non-protein coding RNA 623
93145OLFM2“Soft”Olfactomedin 2
1600DAB1“Soft”DAB adaptor protein 1
767CA8“Soft”Carbonic anhydrase 8
441381LRRC24“Soft”Leucine rich repeat containing 24
81551STMN4“Soft”Stathmin 4
345630FBLL1“Soft”Fibrillarin like 1
Table 2.
Open in new tab

Differentially Expressed Genes: List of Most Stable Differentially Expressed Genes between “Stiff” and “Soft” Biopsies after Patient-wise Leave-one-out Validation

ENTREZ IDGene IDAssociationGene Name
84935MEDAG“Stiff”Mesenteric estrogen dependent Adipogenesis
1378CR1“Stiff”Complement C3b/C4b receptor 1 (Knops blood group)
23213SULF1“Stiff”Sulfatase 1
3875KRT18“Stiff”Keratin 18
9332CD163“Stiff”CD163 molecule
100628315DNM3OS“Stiff”DNM3 opposite strand/antisense RNA
728264CARMN“Stiff”Cardiac mesoderm enhancer-associated noncoding RNA
5325PLAGL1“Stiff”PLAG1 like zinc finger 1
8829NRP1“Stiff”Neuropilin 1
54885TBC1D8B“Stiff”TBC1 domain family member 8B
7373COL14A1“Stiff”Collagen type XIV alpha 1 chain
1282COL4A1“Stiff”Collagen type IV alpha 1 chain
79839CCDC102B“Stiff”Coiled-coil domain containing 102B
1601DAB2“Stiff”DAB adaptor protein 2
3672ITGA1“Stiff”Integrin subunit alpha 1
4121MAN1A1“Stiff”Mannosidase alpha class 1A member 1
55075UACA“Stiff”Uveal autoantigen with coiled-coil domains and ankyrin repeats
5205ATP8B1“Stiff”ATPase phospholipid transporting 8B1
5139PDE3A“Stiff”Phosphodiesterase 3A
22925PLA2R1“Stiff”Phospholipase A2 receptor 1
5592PRKG1“Stiff”Protein kinase cGMP-dependent 1
1909EDNRA“Stiff”Endothelin receptor type A
1290COL5A2“Stiff”Collagen type V alpha 2 chain
1368CPM“Stiff”Carboxypeptidase M
9060PAPSS2“Stiff”3ʹ-phosphoadenosine 5’-phosphosulfate synthase 2
10351ABCA8“Stiff”ATP binding cassette subfamily A member 8
8654PDE5A“Stiff”Phosphodiesterase 5A
3759KCNJ2“Stiff”Potassium inwardly rectifying channel subfamily J member 2
5175PECAM1“Stiff”Platelet and endothelial cell adhesion molEcule 1
2321FLT1“Stiff”Fms related receptor tyrosine kinase 1
115548FCHO2“Stiff”FCH and mu domain containing endocytic adaptor 2
84910TMEM87B“Stiff”Transmembrane protein 87B
9169SCAF11“Stiff”SR-related CTD associated factor 11
23216TBC1D1“Stiff”TBC1 domain family member 1
2803GOLGA4“Stiff”Golgin A4
875CBS“Soft”Cystathionine beta-synthase
728875LINC00623“Soft”Long intergenic non-protein coding RNA 623
93145OLFM2“Soft”Olfactomedin 2
1600DAB1“Soft”DAB adaptor protein 1
767CA8“Soft”Carbonic anhydrase 8
441381LRRC24“Soft”Leucine rich repeat containing 24
81551STMN4“Soft”Stathmin 4
345630FBLL1“Soft”Fibrillarin like 1
ENTREZ IDGene IDAssociationGene Name
84935MEDAG“Stiff”Mesenteric estrogen dependent Adipogenesis
1378CR1“Stiff”Complement C3b/C4b receptor 1 (Knops blood group)
23213SULF1“Stiff”Sulfatase 1
3875KRT18“Stiff”Keratin 18
9332CD163“Stiff”CD163 molecule
100628315DNM3OS“Stiff”DNM3 opposite strand/antisense RNA
728264CARMN“Stiff”Cardiac mesoderm enhancer-associated noncoding RNA
5325PLAGL1“Stiff”PLAG1 like zinc finger 1
8829NRP1“Stiff”Neuropilin 1
54885TBC1D8B“Stiff”TBC1 domain family member 8B
7373COL14A1“Stiff”Collagen type XIV alpha 1 chain
1282COL4A1“Stiff”Collagen type IV alpha 1 chain
79839CCDC102B“Stiff”Coiled-coil domain containing 102B
1601DAB2“Stiff”DAB adaptor protein 2
3672ITGA1“Stiff”Integrin subunit alpha 1
4121MAN1A1“Stiff”Mannosidase alpha class 1A member 1
55075UACA“Stiff”Uveal autoantigen with coiled-coil domains and ankyrin repeats
5205ATP8B1“Stiff”ATPase phospholipid transporting 8B1
5139PDE3A“Stiff”Phosphodiesterase 3A
22925PLA2R1“Stiff”Phospholipase A2 receptor 1
5592PRKG1“Stiff”Protein kinase cGMP-dependent 1
1909EDNRA“Stiff”Endothelin receptor type A
1290COL5A2“Stiff”Collagen type V alpha 2 chain
1368CPM“Stiff”Carboxypeptidase M
9060PAPSS2“Stiff”3ʹ-phosphoadenosine 5’-phosphosulfate synthase 2
10351ABCA8“Stiff”ATP binding cassette subfamily A member 8
8654PDE5A“Stiff”Phosphodiesterase 5A
3759KCNJ2“Stiff”Potassium inwardly rectifying channel subfamily J member 2
5175PECAM1“Stiff”Platelet and endothelial cell adhesion molEcule 1
2321FLT1“Stiff”Fms related receptor tyrosine kinase 1
115548FCHO2“Stiff”FCH and mu domain containing endocytic adaptor 2
84910TMEM87B“Stiff”Transmembrane protein 87B
9169SCAF11“Stiff”SR-related CTD associated factor 11
23216TBC1D1“Stiff”TBC1 domain family member 1
2803GOLGA4“Stiff”Golgin A4
875CBS“Soft”Cystathionine beta-synthase
728875LINC00623“Soft”Long intergenic non-protein coding RNA 623
93145OLFM2“Soft”Olfactomedin 2
1600DAB1“Soft”DAB adaptor protein 1
767CA8“Soft”Carbonic anhydrase 8
441381LRRC24“Soft”Leucine rich repeat containing 24
81551STMN4“Soft”Stathmin 4
345630FBLL1“Soft”Fibrillarin like 1
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