Table 2.

Patient demographics, health metrics, weight, and weight loss.

PATHWEIGH (N = 416)SOC (N = 165)P-value
Age
 Mean (SD)49.9 (15.9)48.9 (15.8)0.482
Sex
 Female246 (59.1%)56 (33.9%)<0.001
 Male170 (40.9%)109 (66.1%)
Race/ethnicity
 Non-Hispanic White305 (73.3%)136 (82.4%)0.001
 Black12 (2.9%)3 (1.8%)
 Hispanic73 (17.5%)11 (6.7%)
 Other26 (6.2%)15 (9.1%)
Insurance
 Tricare30 (7.2%)6 (3.6%)0.038
 Commercial254 (61.1%)108 (65.5%)
 Medicare71 (17.1%)33 (20.0%)
 Colorado Medicaid35 (8.4%)4 (2.4%)
 Managed Medicare13 (3.1%)9 (5.5%)
 Other/Self-Pay13 (3.1%)5 (3.0%)
Number of comorbidities (numeric)
 Mean (SD)0.7 (0.8)0.4 (0.6)<0.001
Number of comorbidities
 0203 (48.8%)113 (68.5%)
 1–2213 (51.2%)52 (31.5%)
 3–514 (3.4%)2 (1.2%)
Using oxygen or CPAP80 (19.2%)29 (17.6%)
A1C (%)
 Mean (SD)6.4 (1.5)6.3 (1.6)
 Missing254124
TSH (mIU/L)
 Mean (SD)3.8 (9.8)2.0 (1.3)
 Missing287123
TG (mg/dl)
 Mean (SD)181.8 (118.5)165.1 (126.9)
 Missing290114
HDL (mg/dl)
 Mean (SD)45.3 (12.8)45.6 (10.7)
 Missing290114
ALT (U/L)
 Mean (SD)38.1 (44.0)73.2 (78.0)
 Missing381156
AST (U/L)
 Mean (SD)30.1 (23.1)49.7 (56.9)
 Missing380156
Binge eating21 (5.0%)2 (1.2%)
PHQ-8 score
 Mean (SD)1.8 (4.4)0.5 (1.6)<0.001
 Missing110
PHQ-9 score
 Mean (SD)6.9 (5.9)3.9 (4.0)<0.001
 Missing239110
Baseline BMI (kg/m2)
 Mean (SD)36.0 (7.7)32.0 (7.0)<0.001
Weight loss (kg)
 Mean (SD)1.2 (5.8)1.2 (5.1)0.991
Weight loss rate (kg/month)
 Mean (SD)0.2 (2.7)0.5 (1.8)0.212
>5% weight loss59 (14.2%)21 (12.7%)0.691
>10% weight loss15 (3.6%)8 (4.8%)0.485
>15% weight loss7 (1.7%)2 (1.2%)1.000
Follow-up duration (days)
 Mean (SD)152.8 (99.7)155.4 (96.0)0.779
Number of weight-prioritized visits
 Median (Q1, Q3)1.0 (1.0, 2.0)1.0 (1.0, 1.0)<0.001
PATHWEIGH (N = 416)SOC (N = 165)P-value
Age
 Mean (SD)49.9 (15.9)48.9 (15.8)0.482
Sex
 Female246 (59.1%)56 (33.9%)<0.001
 Male170 (40.9%)109 (66.1%)
Race/ethnicity
 Non-Hispanic White305 (73.3%)136 (82.4%)0.001
 Black12 (2.9%)3 (1.8%)
 Hispanic73 (17.5%)11 (6.7%)
 Other26 (6.2%)15 (9.1%)
Insurance
 Tricare30 (7.2%)6 (3.6%)0.038
 Commercial254 (61.1%)108 (65.5%)
 Medicare71 (17.1%)33 (20.0%)
 Colorado Medicaid35 (8.4%)4 (2.4%)
 Managed Medicare13 (3.1%)9 (5.5%)
 Other/Self-Pay13 (3.1%)5 (3.0%)
Number of comorbidities (numeric)
 Mean (SD)0.7 (0.8)0.4 (0.6)<0.001
Number of comorbidities
 0203 (48.8%)113 (68.5%)
 1–2213 (51.2%)52 (31.5%)
 3–514 (3.4%)2 (1.2%)
Using oxygen or CPAP80 (19.2%)29 (17.6%)
A1C (%)
 Mean (SD)6.4 (1.5)6.3 (1.6)
 Missing254124
TSH (mIU/L)
 Mean (SD)3.8 (9.8)2.0 (1.3)
 Missing287123
TG (mg/dl)
 Mean (SD)181.8 (118.5)165.1 (126.9)
 Missing290114
HDL (mg/dl)
 Mean (SD)45.3 (12.8)45.6 (10.7)
 Missing290114
ALT (U/L)
 Mean (SD)38.1 (44.0)73.2 (78.0)
 Missing381156
AST (U/L)
 Mean (SD)30.1 (23.1)49.7 (56.9)
 Missing380156
Binge eating21 (5.0%)2 (1.2%)
PHQ-8 score
 Mean (SD)1.8 (4.4)0.5 (1.6)<0.001
 Missing110
PHQ-9 score
 Mean (SD)6.9 (5.9)3.9 (4.0)<0.001
 Missing239110
Baseline BMI (kg/m2)
 Mean (SD)36.0 (7.7)32.0 (7.0)<0.001
Weight loss (kg)
 Mean (SD)1.2 (5.8)1.2 (5.1)0.991
Weight loss rate (kg/month)
 Mean (SD)0.2 (2.7)0.5 (1.8)0.212
>5% weight loss59 (14.2%)21 (12.7%)0.691
>10% weight loss15 (3.6%)8 (4.8%)0.485
>15% weight loss7 (1.7%)2 (1.2%)1.000
Follow-up duration (days)
 Mean (SD)152.8 (99.7)155.4 (96.0)0.779
Number of weight-prioritized visits
 Median (Q1, Q3)1.0 (1.0, 2.0)1.0 (1.0, 1.0)<0.001

ALT, alanine transaminase; AST, aspartate transaminase; CPAP, continuous positive airway pressure; HDL, high-density lipoprotein.

Table 2.

Patient demographics, health metrics, weight, and weight loss.

PATHWEIGH (N = 416)SOC (N = 165)P-value
Age
 Mean (SD)49.9 (15.9)48.9 (15.8)0.482
Sex
 Female246 (59.1%)56 (33.9%)<0.001
 Male170 (40.9%)109 (66.1%)
Race/ethnicity
 Non-Hispanic White305 (73.3%)136 (82.4%)0.001
 Black12 (2.9%)3 (1.8%)
 Hispanic73 (17.5%)11 (6.7%)
 Other26 (6.2%)15 (9.1%)
Insurance
 Tricare30 (7.2%)6 (3.6%)0.038
 Commercial254 (61.1%)108 (65.5%)
 Medicare71 (17.1%)33 (20.0%)
 Colorado Medicaid35 (8.4%)4 (2.4%)
 Managed Medicare13 (3.1%)9 (5.5%)
 Other/Self-Pay13 (3.1%)5 (3.0%)
Number of comorbidities (numeric)
 Mean (SD)0.7 (0.8)0.4 (0.6)<0.001
Number of comorbidities
 0203 (48.8%)113 (68.5%)
 1–2213 (51.2%)52 (31.5%)
 3–514 (3.4%)2 (1.2%)
Using oxygen or CPAP80 (19.2%)29 (17.6%)
A1C (%)
 Mean (SD)6.4 (1.5)6.3 (1.6)
 Missing254124
TSH (mIU/L)
 Mean (SD)3.8 (9.8)2.0 (1.3)
 Missing287123
TG (mg/dl)
 Mean (SD)181.8 (118.5)165.1 (126.9)
 Missing290114
HDL (mg/dl)
 Mean (SD)45.3 (12.8)45.6 (10.7)
 Missing290114
ALT (U/L)
 Mean (SD)38.1 (44.0)73.2 (78.0)
 Missing381156
AST (U/L)
 Mean (SD)30.1 (23.1)49.7 (56.9)
 Missing380156
Binge eating21 (5.0%)2 (1.2%)
PHQ-8 score
 Mean (SD)1.8 (4.4)0.5 (1.6)<0.001
 Missing110
PHQ-9 score
 Mean (SD)6.9 (5.9)3.9 (4.0)<0.001
 Missing239110
Baseline BMI (kg/m2)
 Mean (SD)36.0 (7.7)32.0 (7.0)<0.001
Weight loss (kg)
 Mean (SD)1.2 (5.8)1.2 (5.1)0.991
Weight loss rate (kg/month)
 Mean (SD)0.2 (2.7)0.5 (1.8)0.212
>5% weight loss59 (14.2%)21 (12.7%)0.691
>10% weight loss15 (3.6%)8 (4.8%)0.485
>15% weight loss7 (1.7%)2 (1.2%)1.000
Follow-up duration (days)
 Mean (SD)152.8 (99.7)155.4 (96.0)0.779
Number of weight-prioritized visits
 Median (Q1, Q3)1.0 (1.0, 2.0)1.0 (1.0, 1.0)<0.001
PATHWEIGH (N = 416)SOC (N = 165)P-value
Age
 Mean (SD)49.9 (15.9)48.9 (15.8)0.482
Sex
 Female246 (59.1%)56 (33.9%)<0.001
 Male170 (40.9%)109 (66.1%)
Race/ethnicity
 Non-Hispanic White305 (73.3%)136 (82.4%)0.001
 Black12 (2.9%)3 (1.8%)
 Hispanic73 (17.5%)11 (6.7%)
 Other26 (6.2%)15 (9.1%)
Insurance
 Tricare30 (7.2%)6 (3.6%)0.038
 Commercial254 (61.1%)108 (65.5%)
 Medicare71 (17.1%)33 (20.0%)
 Colorado Medicaid35 (8.4%)4 (2.4%)
 Managed Medicare13 (3.1%)9 (5.5%)
 Other/Self-Pay13 (3.1%)5 (3.0%)
Number of comorbidities (numeric)
 Mean (SD)0.7 (0.8)0.4 (0.6)<0.001
Number of comorbidities
 0203 (48.8%)113 (68.5%)
 1–2213 (51.2%)52 (31.5%)
 3–514 (3.4%)2 (1.2%)
Using oxygen or CPAP80 (19.2%)29 (17.6%)
A1C (%)
 Mean (SD)6.4 (1.5)6.3 (1.6)
 Missing254124
TSH (mIU/L)
 Mean (SD)3.8 (9.8)2.0 (1.3)
 Missing287123
TG (mg/dl)
 Mean (SD)181.8 (118.5)165.1 (126.9)
 Missing290114
HDL (mg/dl)
 Mean (SD)45.3 (12.8)45.6 (10.7)
 Missing290114
ALT (U/L)
 Mean (SD)38.1 (44.0)73.2 (78.0)
 Missing381156
AST (U/L)
 Mean (SD)30.1 (23.1)49.7 (56.9)
 Missing380156
Binge eating21 (5.0%)2 (1.2%)
PHQ-8 score
 Mean (SD)1.8 (4.4)0.5 (1.6)<0.001
 Missing110
PHQ-9 score
 Mean (SD)6.9 (5.9)3.9 (4.0)<0.001
 Missing239110
Baseline BMI (kg/m2)
 Mean (SD)36.0 (7.7)32.0 (7.0)<0.001
Weight loss (kg)
 Mean (SD)1.2 (5.8)1.2 (5.1)0.991
Weight loss rate (kg/month)
 Mean (SD)0.2 (2.7)0.5 (1.8)0.212
>5% weight loss59 (14.2%)21 (12.7%)0.691
>10% weight loss15 (3.6%)8 (4.8%)0.485
>15% weight loss7 (1.7%)2 (1.2%)1.000
Follow-up duration (days)
 Mean (SD)152.8 (99.7)155.4 (96.0)0.779
Number of weight-prioritized visits
 Median (Q1, Q3)1.0 (1.0, 2.0)1.0 (1.0, 1.0)<0.001

ALT, alanine transaminase; AST, aspartate transaminase; CPAP, continuous positive airway pressure; HDL, high-density lipoprotein.

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