Per-Person Mean Concentrations of Bacterial Species DNA Measured as 16S Ribosomal RNA Gene Copies/Swab by Quantitative Polymerase Chain Reaction
| Bacteria . | Average Log10 Copies/Swab, Observational . | Average Log10 Copies/Swab, on Valacyclovir . | Change, Valacyclovir vs Baseline (95% CI) . | P Value . |
|---|---|---|---|---|
| Gardnerella spp | 5.9 | 6.3 | 0.4 (−.1 to .9) | .13 |
| Megasphaera spp | 3.8 | 3.4 | −0.4 (−1.0 to .2) | .21 |
| BVAB-2 | 3.2 | 2.9 | −0.2 (−.7 to .3) | .36 |
| Lactobacillus crispatus | 3.9 | 4.3 | 0.5 (−.1 to 1.0) | .10 |
| Lactobacillus iners | 7.5 | 7.4 | −0.1 (−.4 to .3) | .85 |
| Lactobacillus jensenii | 3.9 | 4.1 | 0.2 (−.3 to .8) | .41 |
| Bacteria . | Average Log10 Copies/Swab, Observational . | Average Log10 Copies/Swab, on Valacyclovir . | Change, Valacyclovir vs Baseline (95% CI) . | P Value . |
|---|---|---|---|---|
| Gardnerella spp | 5.9 | 6.3 | 0.4 (−.1 to .9) | .13 |
| Megasphaera spp | 3.8 | 3.4 | −0.4 (−1.0 to .2) | .21 |
| BVAB-2 | 3.2 | 2.9 | −0.2 (−.7 to .3) | .36 |
| Lactobacillus crispatus | 3.9 | 4.3 | 0.5 (−.1 to 1.0) | .10 |
| Lactobacillus iners | 7.5 | 7.4 | −0.1 (−.4 to .3) | .85 |
| Lactobacillus jensenii | 3.9 | 4.1 | 0.2 (−.3 to .8) | .41 |
Abbreviations: BVAB-2, bacterial vaginosis–associated bacterium 2; CI, confidence interval.
Per-Person Mean Concentrations of Bacterial Species DNA Measured as 16S Ribosomal RNA Gene Copies/Swab by Quantitative Polymerase Chain Reaction
| Bacteria . | Average Log10 Copies/Swab, Observational . | Average Log10 Copies/Swab, on Valacyclovir . | Change, Valacyclovir vs Baseline (95% CI) . | P Value . |
|---|---|---|---|---|
| Gardnerella spp | 5.9 | 6.3 | 0.4 (−.1 to .9) | .13 |
| Megasphaera spp | 3.8 | 3.4 | −0.4 (−1.0 to .2) | .21 |
| BVAB-2 | 3.2 | 2.9 | −0.2 (−.7 to .3) | .36 |
| Lactobacillus crispatus | 3.9 | 4.3 | 0.5 (−.1 to 1.0) | .10 |
| Lactobacillus iners | 7.5 | 7.4 | −0.1 (−.4 to .3) | .85 |
| Lactobacillus jensenii | 3.9 | 4.1 | 0.2 (−.3 to .8) | .41 |
| Bacteria . | Average Log10 Copies/Swab, Observational . | Average Log10 Copies/Swab, on Valacyclovir . | Change, Valacyclovir vs Baseline (95% CI) . | P Value . |
|---|---|---|---|---|
| Gardnerella spp | 5.9 | 6.3 | 0.4 (−.1 to .9) | .13 |
| Megasphaera spp | 3.8 | 3.4 | −0.4 (−1.0 to .2) | .21 |
| BVAB-2 | 3.2 | 2.9 | −0.2 (−.7 to .3) | .36 |
| Lactobacillus crispatus | 3.9 | 4.3 | 0.5 (−.1 to 1.0) | .10 |
| Lactobacillus iners | 7.5 | 7.4 | −0.1 (−.4 to .3) | .85 |
| Lactobacillus jensenii | 3.9 | 4.1 | 0.2 (−.3 to .8) | .41 |
Abbreviations: BVAB-2, bacterial vaginosis–associated bacterium 2; CI, confidence interval.
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