Table 2
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Characteristic of DTI datasets, where different colors denotes similarities derived from data diverse sources.

DatasetNRGPCRICELuo
Drug54223210445708
Target26952046641512
Interaction1661096233142561923
Sparsity0.1180.0520.0540.0140.002
Drug Similarity (Source) |$^\ddag$|SIMCOMP, LAMBDA, MARG, MINMAX, SPEC, TAN (CS) ; AERS-b, AERS-f, SIDER (SE)TAN (CS), DDI, DIA, SE
Target Similarity (Source)|$^\S$|SW, MIS-k3m1, MIS-k4m1, MIS-k3m2, MIS-k4m2, SPEC-k3, SPEC-k4 (AAS) ; PPI; GOSW (AAS), PPI, TIA
DatasetNRGPCRICELuo
Drug54223210445708
Target26952046641512
Interaction1661096233142561923
Sparsity0.1180.0520.0540.0140.002
Drug Similarity (Source) |$^\ddag$|SIMCOMP, LAMBDA, MARG, MINMAX, SPEC, TAN (CS) ; AERS-b, AERS-f, SIDER (SE)TAN (CS), DDI, DIA, SE
Target Similarity (Source)|$^\S$|SW, MIS-k3m1, MIS-k4m1, MIS-k3m2, MIS-k4m2, SPEC-k3, SPEC-k4 (AAS) ; PPI; GOSW (AAS), PPI, TIA

|$\ddag$| CS: chemical structure, SE: drug side effect, DDI: drug–drug interaction, DIA: drug–disease association |$\S$| AAS: amino-acid sequence, PPI: protein–protein interaction, GO: Gene Ontology annotation, TIA: target–disease association

Table 2
Open in new tab

Characteristic of DTI datasets, where different colors denotes similarities derived from data diverse sources.

DatasetNRGPCRICELuo
Drug54223210445708
Target26952046641512
Interaction1661096233142561923
Sparsity0.1180.0520.0540.0140.002
Drug Similarity (Source) |$^\ddag$|SIMCOMP, LAMBDA, MARG, MINMAX, SPEC, TAN (CS) ; AERS-b, AERS-f, SIDER (SE)TAN (CS), DDI, DIA, SE
Target Similarity (Source)|$^\S$|SW, MIS-k3m1, MIS-k4m1, MIS-k3m2, MIS-k4m2, SPEC-k3, SPEC-k4 (AAS) ; PPI; GOSW (AAS), PPI, TIA
DatasetNRGPCRICELuo
Drug54223210445708
Target26952046641512
Interaction1661096233142561923
Sparsity0.1180.0520.0540.0140.002
Drug Similarity (Source) |$^\ddag$|SIMCOMP, LAMBDA, MARG, MINMAX, SPEC, TAN (CS) ; AERS-b, AERS-f, SIDER (SE)TAN (CS), DDI, DIA, SE
Target Similarity (Source)|$^\S$|SW, MIS-k3m1, MIS-k4m1, MIS-k3m2, MIS-k4m2, SPEC-k3, SPEC-k4 (AAS) ; PPI; GOSW (AAS), PPI, TIA

|$\ddag$| CS: chemical structure, SE: drug side effect, DDI: drug–drug interaction, DIA: drug–disease association |$\S$| AAS: amino-acid sequence, PPI: protein–protein interaction, GO: Gene Ontology annotation, TIA: target–disease association

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