Table 1

Genes of PCR array whose expression was up- or down-regulated in hMSCs by at least two-fold following exposure of the cells to plaque

Acc. No.SymbolDescriptionsRelative expressiona
Plaque/intimaPool/control
NM_001200BMP2Bone morphogenetic protein 22.019.3
NM_002986CCL11Chemokine (C-C motif) ligand 11; eotaxin4.03.4
NM_005408CCL13Chemokine (C-C motif) ligand 13; MCP-42.02.1
NM_002988CCL18Chemokine (C-C motif) ligand 18; PARC4.73.3
NM_000759CSF3Colony stimulating factor 3; G-CSF−2.3−3.7
NM_002089CXCL2Chemokine (C-X-C motif) ligand 2; GRO beta2.811.7
NM_000576IL1BInterleukin 1, beta3.912.6
NM_000589IL4Interleukin 41.84.9
NM_000600IL6Interleukin 61.33.6
NM_002188IL13Interleukin 135.53.4
NM_052872IL17FInterleukin 17F6.44.5
NM_006850IL24Interleukin 242.316.3
NM_145659IL27Interleukin 272.22.4
NM_005259MSTNMyostatin4.34.2
NM_003810TNFSF10Tumour necrosis factor (ligand) superfamily, member 10; TRAIL2.468.7
Acc. No.SymbolDescriptionsRelative expressiona
Plaque/intimaPool/control
NM_001200BMP2Bone morphogenetic protein 22.019.3
NM_002986CCL11Chemokine (C-C motif) ligand 11; eotaxin4.03.4
NM_005408CCL13Chemokine (C-C motif) ligand 13; MCP-42.02.1
NM_002988CCL18Chemokine (C-C motif) ligand 18; PARC4.73.3
NM_000759CSF3Colony stimulating factor 3; G-CSF−2.3−3.7
NM_002089CXCL2Chemokine (C-X-C motif) ligand 2; GRO beta2.811.7
NM_000576IL1BInterleukin 1, beta3.912.6
NM_000589IL4Interleukin 41.84.9
NM_000600IL6Interleukin 61.33.6
NM_002188IL13Interleukin 135.53.4
NM_052872IL17FInterleukin 17F6.44.5
NM_006850IL24Interleukin 242.316.3
NM_145659IL27Interleukin 272.22.4
NM_005259MSTNMyostatin4.34.2
NM_003810TNFSF10Tumour necrosis factor (ligand) superfamily, member 10; TRAIL2.468.7
a

Genes consistently regulated in both comparison groups: plaque relative to intima (set as 1) and pooled plaques relative to untreated control cells (set as 1).

Table 1

Genes of PCR array whose expression was up- or down-regulated in hMSCs by at least two-fold following exposure of the cells to plaque

Acc. No.SymbolDescriptionsRelative expressiona
Plaque/intimaPool/control
NM_001200BMP2Bone morphogenetic protein 22.019.3
NM_002986CCL11Chemokine (C-C motif) ligand 11; eotaxin4.03.4
NM_005408CCL13Chemokine (C-C motif) ligand 13; MCP-42.02.1
NM_002988CCL18Chemokine (C-C motif) ligand 18; PARC4.73.3
NM_000759CSF3Colony stimulating factor 3; G-CSF−2.3−3.7
NM_002089CXCL2Chemokine (C-X-C motif) ligand 2; GRO beta2.811.7
NM_000576IL1BInterleukin 1, beta3.912.6
NM_000589IL4Interleukin 41.84.9
NM_000600IL6Interleukin 61.33.6
NM_002188IL13Interleukin 135.53.4
NM_052872IL17FInterleukin 17F6.44.5
NM_006850IL24Interleukin 242.316.3
NM_145659IL27Interleukin 272.22.4
NM_005259MSTNMyostatin4.34.2
NM_003810TNFSF10Tumour necrosis factor (ligand) superfamily, member 10; TRAIL2.468.7
Acc. No.SymbolDescriptionsRelative expressiona
Plaque/intimaPool/control
NM_001200BMP2Bone morphogenetic protein 22.019.3
NM_002986CCL11Chemokine (C-C motif) ligand 11; eotaxin4.03.4
NM_005408CCL13Chemokine (C-C motif) ligand 13; MCP-42.02.1
NM_002988CCL18Chemokine (C-C motif) ligand 18; PARC4.73.3
NM_000759CSF3Colony stimulating factor 3; G-CSF−2.3−3.7
NM_002089CXCL2Chemokine (C-X-C motif) ligand 2; GRO beta2.811.7
NM_000576IL1BInterleukin 1, beta3.912.6
NM_000589IL4Interleukin 41.84.9
NM_000600IL6Interleukin 61.33.6
NM_002188IL13Interleukin 135.53.4
NM_052872IL17FInterleukin 17F6.44.5
NM_006850IL24Interleukin 242.316.3
NM_145659IL27Interleukin 272.22.4
NM_005259MSTNMyostatin4.34.2
NM_003810TNFSF10Tumour necrosis factor (ligand) superfamily, member 10; TRAIL2.468.7
a

Genes consistently regulated in both comparison groups: plaque relative to intima (set as 1) and pooled plaques relative to untreated control cells (set as 1).

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