Table 1

Demographics and clinical characteristics of the cohort (N = 508 patients)

CharacteristicsValues
Female, n (%)460 (92%)
Age at diagnosis, years, mean (s.d.)40.7 (21.0)
Disease duration at enrolment, years, mean (s.d.)10.8 (9.9)
Age at enrolment, years, mean (s.d.)50.4 (13.7)
SLICC 2012 criteria (ever present)
 Clinical criteria, n (%)
  Acute cutaneous lupus262 (51.57)
  Chronic cutaneous lupus57 (11.22)
  Oral or nasal ulcers171 (33.66)
  Non-scaring alopecia156 (30.71)
  Arthritis355 (69.88)
  Serositis96 (18.9)
  Renal158 (31.1)
  Neurologic32 (6.3)
  Haemolytic anaemia29 (5.7)
  Leukopenia219 (43.11)
  Thrombocytopenia88 (17.3)
Immunological criteria, n (%)
  ANA489 (96.26)
  Anti-dsDNA antibodies329 (64.76)
  Anti-Sm antibodies95 (18.7)
  Anti-phospholipid antibodies163 (32.09)
  Low complement levels306 (60.24)
Number of SLICC criteria for SLE, n (%)6.2 (2.2)
SLEDAI-2K score at enrolment, mean (s.d.)2.8 (3.3)
SLICC/ACR-DI score at enrolment mean (s.d.)0.96 (1.4)
Damage present at enrolment, n (%)253 (49.8)
Clinical SLEDAI-2K score, mean (s.d.)1.6 (2.7)
Current hypocomplementemia, n (%)152 (29.9)
Current elevated anti-dsDNA, n (%)125 (24.6)
PGA at enrolment, mean (s.d.)0.2 (0.49)
CharacteristicsValues
Female, n (%)460 (92%)
Age at diagnosis, years, mean (s.d.)40.7 (21.0)
Disease duration at enrolment, years, mean (s.d.)10.8 (9.9)
Age at enrolment, years, mean (s.d.)50.4 (13.7)
SLICC 2012 criteria (ever present)
 Clinical criteria, n (%)
  Acute cutaneous lupus262 (51.57)
  Chronic cutaneous lupus57 (11.22)
  Oral or nasal ulcers171 (33.66)
  Non-scaring alopecia156 (30.71)
  Arthritis355 (69.88)
  Serositis96 (18.9)
  Renal158 (31.1)
  Neurologic32 (6.3)
  Haemolytic anaemia29 (5.7)
  Leukopenia219 (43.11)
  Thrombocytopenia88 (17.3)
Immunological criteria, n (%)
  ANA489 (96.26)
  Anti-dsDNA antibodies329 (64.76)
  Anti-Sm antibodies95 (18.7)
  Anti-phospholipid antibodies163 (32.09)
  Low complement levels306 (60.24)
Number of SLICC criteria for SLE, n (%)6.2 (2.2)
SLEDAI-2K score at enrolment, mean (s.d.)2.8 (3.3)
SLICC/ACR-DI score at enrolment mean (s.d.)0.96 (1.4)
Damage present at enrolment, n (%)253 (49.8)
Clinical SLEDAI-2K score, mean (s.d.)1.6 (2.7)
Current hypocomplementemia, n (%)152 (29.9)
Current elevated anti-dsDNA, n (%)125 (24.6)
PGA at enrolment, mean (s.d.)0.2 (0.49)
Table 1

Demographics and clinical characteristics of the cohort (N = 508 patients)

CharacteristicsValues
Female, n (%)460 (92%)
Age at diagnosis, years, mean (s.d.)40.7 (21.0)
Disease duration at enrolment, years, mean (s.d.)10.8 (9.9)
Age at enrolment, years, mean (s.d.)50.4 (13.7)
SLICC 2012 criteria (ever present)
 Clinical criteria, n (%)
  Acute cutaneous lupus262 (51.57)
  Chronic cutaneous lupus57 (11.22)
  Oral or nasal ulcers171 (33.66)
  Non-scaring alopecia156 (30.71)
  Arthritis355 (69.88)
  Serositis96 (18.9)
  Renal158 (31.1)
  Neurologic32 (6.3)
  Haemolytic anaemia29 (5.7)
  Leukopenia219 (43.11)
  Thrombocytopenia88 (17.3)
Immunological criteria, n (%)
  ANA489 (96.26)
  Anti-dsDNA antibodies329 (64.76)
  Anti-Sm antibodies95 (18.7)
  Anti-phospholipid antibodies163 (32.09)
  Low complement levels306 (60.24)
Number of SLICC criteria for SLE, n (%)6.2 (2.2)
SLEDAI-2K score at enrolment, mean (s.d.)2.8 (3.3)
SLICC/ACR-DI score at enrolment mean (s.d.)0.96 (1.4)
Damage present at enrolment, n (%)253 (49.8)
Clinical SLEDAI-2K score, mean (s.d.)1.6 (2.7)
Current hypocomplementemia, n (%)152 (29.9)
Current elevated anti-dsDNA, n (%)125 (24.6)
PGA at enrolment, mean (s.d.)0.2 (0.49)
CharacteristicsValues
Female, n (%)460 (92%)
Age at diagnosis, years, mean (s.d.)40.7 (21.0)
Disease duration at enrolment, years, mean (s.d.)10.8 (9.9)
Age at enrolment, years, mean (s.d.)50.4 (13.7)
SLICC 2012 criteria (ever present)
 Clinical criteria, n (%)
  Acute cutaneous lupus262 (51.57)
  Chronic cutaneous lupus57 (11.22)
  Oral or nasal ulcers171 (33.66)
  Non-scaring alopecia156 (30.71)
  Arthritis355 (69.88)
  Serositis96 (18.9)
  Renal158 (31.1)
  Neurologic32 (6.3)
  Haemolytic anaemia29 (5.7)
  Leukopenia219 (43.11)
  Thrombocytopenia88 (17.3)
Immunological criteria, n (%)
  ANA489 (96.26)
  Anti-dsDNA antibodies329 (64.76)
  Anti-Sm antibodies95 (18.7)
  Anti-phospholipid antibodies163 (32.09)
  Low complement levels306 (60.24)
Number of SLICC criteria for SLE, n (%)6.2 (2.2)
SLEDAI-2K score at enrolment, mean (s.d.)2.8 (3.3)
SLICC/ACR-DI score at enrolment mean (s.d.)0.96 (1.4)
Damage present at enrolment, n (%)253 (49.8)
Clinical SLEDAI-2K score, mean (s.d.)1.6 (2.7)
Current hypocomplementemia, n (%)152 (29.9)
Current elevated anti-dsDNA, n (%)125 (24.6)
PGA at enrolment, mean (s.d.)0.2 (0.49)
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