Table 1.

Demographic and clinical characteristics of the groups

ParametersSurvivor (n = 48)Nonsurvivor (n = 43)P value
Sex
 Male26 (54.2%)24 (55.8%)0.875a
 Female22 (45.8%)19 (44.2%)
Age, years75 (65–84)71 (63–84)0.247b
BMI, kg/m224.6 (23.3–27.8)25.95 (22.8–31.2)0.209b
Comorbid diseases
 Cardiovascular disease26 (54.2%)22 (51.2%)0.774a
 Diabetes mellitus16 (33.3%)21 (48.8%)0.133a
 Hypertension43 (89.6%)30 (69.8%)0.018a
 Chronic lung disease13 (27.1%)10 (23.3 %)0.675a
 Number of comorbid diseases
  18 (16.7%)8 (16.7%)0.808a
  232 (66.7%)30 (69.8%)0.751a
  37 (14.6%)5 (11.6%)0.677a
  41 (2.1%)00.341a
 Glucose, mg/dl145 (116–234)172 (137–238)0.061b
 Urea, mg/dl54 (42–71)60 (39–73)0.877b
 Creatine, mg/dl1 (0.81–1.22)1 (0.8–1.38)0.937b
 Sodium, mmol/l137 (133–139)138 (134–142)0.232b
 Potassium, mmol/l3.92 (3.34–4.43)4.2 (3.54–4.6)0.180b
 AST, U/l26 (18–58)27 (23–43)0.946b
 ALT, U/l18 (12–27)18 (15–24)0.696b
 Albumin, g/dl2.77 (2.5–3.2)2.75 (2.53–2.99)0.382b
 CRP, mg/dl7.41 (2.1–12.5)9.9 (3.8–16)0.278b
 D-dimer, ug/l1446 (849–2320)1610 (923–3380)0.373b
 Arterial blood gas analysis
  pH7.39 (7.37–7.45)7.40 (7.33–7.45)0.349b
  pCO2, mmHg39 (32–42)36 (34–45)0.656b
  HCO3, mmol/l24 (22–25)22 (20–25)0.044b
 ONSD, mm4.15 (4.06–4.25)5.95 (5.8–6.25)<0.001b
 APACHE II score8 (8–9)12 (10–15)<0.001b
 SOFA score2 (2–2)3 (3–4)<0.001b
 GCS score15 (15–15)14 (11–15)<0.001b
 PaO2:FiO2 ratio, mmHg227 (200–250)130 (120–160)<0.001b
 IMV9 (19%)32 (74%)<0.001a
 NIV39 (81.3%)11 (25.6%)
 Length of ICU stay, day4 (3–9)8 (6–14)<0.001b
ParametersSurvivor (n = 48)Nonsurvivor (n = 43)P value
Sex
 Male26 (54.2%)24 (55.8%)0.875a
 Female22 (45.8%)19 (44.2%)
Age, years75 (65–84)71 (63–84)0.247b
BMI, kg/m224.6 (23.3–27.8)25.95 (22.8–31.2)0.209b
Comorbid diseases
 Cardiovascular disease26 (54.2%)22 (51.2%)0.774a
 Diabetes mellitus16 (33.3%)21 (48.8%)0.133a
 Hypertension43 (89.6%)30 (69.8%)0.018a
 Chronic lung disease13 (27.1%)10 (23.3 %)0.675a
 Number of comorbid diseases
  18 (16.7%)8 (16.7%)0.808a
  232 (66.7%)30 (69.8%)0.751a
  37 (14.6%)5 (11.6%)0.677a
  41 (2.1%)00.341a
 Glucose, mg/dl145 (116–234)172 (137–238)0.061b
 Urea, mg/dl54 (42–71)60 (39–73)0.877b
 Creatine, mg/dl1 (0.81–1.22)1 (0.8–1.38)0.937b
 Sodium, mmol/l137 (133–139)138 (134–142)0.232b
 Potassium, mmol/l3.92 (3.34–4.43)4.2 (3.54–4.6)0.180b
 AST, U/l26 (18–58)27 (23–43)0.946b
 ALT, U/l18 (12–27)18 (15–24)0.696b
 Albumin, g/dl2.77 (2.5–3.2)2.75 (2.53–2.99)0.382b
 CRP, mg/dl7.41 (2.1–12.5)9.9 (3.8–16)0.278b
 D-dimer, ug/l1446 (849–2320)1610 (923–3380)0.373b
 Arterial blood gas analysis
  pH7.39 (7.37–7.45)7.40 (7.33–7.45)0.349b
  pCO2, mmHg39 (32–42)36 (34–45)0.656b
  HCO3, mmol/l24 (22–25)22 (20–25)0.044b
 ONSD, mm4.15 (4.06–4.25)5.95 (5.8–6.25)<0.001b
 APACHE II score8 (8–9)12 (10–15)<0.001b
 SOFA score2 (2–2)3 (3–4)<0.001b
 GCS score15 (15–15)14 (11–15)<0.001b
 PaO2:FiO2 ratio, mmHg227 (200–250)130 (120–160)<0.001b
 IMV9 (19%)32 (74%)<0.001a
 NIV39 (81.3%)11 (25.6%)
 Length of ICU stay, day4 (3–9)8 (6–14)<0.001b

Categorical data shown as number (percentage). Non-normally distributed continuous variables displayed as median (interquartile range). P < 0.05: significant (shown in bold).

BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CRP, C-reactive protein; pH, potential of hydrogen; PCO2, carbon dioxide arterial partial pressure; HCO3, bicarbonate; ONSD, optic nerve sheath diameter; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; GCS, Glasgow Coma Scale; PaO2:FiO2, arterial blood gas and arterial partial pressure of oxygen:fraction of inspired oxygen; IMV, invasive mechanical ventilation; NIV, non-invasive mechanical ventilation; ICU, intensive care unit.

a

Chi-square test,.

b

Mann–Whitney’s test.

Table 1.

Demographic and clinical characteristics of the groups

ParametersSurvivor (n = 48)Nonsurvivor (n = 43)P value
Sex
 Male26 (54.2%)24 (55.8%)0.875a
 Female22 (45.8%)19 (44.2%)
Age, years75 (65–84)71 (63–84)0.247b
BMI, kg/m224.6 (23.3–27.8)25.95 (22.8–31.2)0.209b
Comorbid diseases
 Cardiovascular disease26 (54.2%)22 (51.2%)0.774a
 Diabetes mellitus16 (33.3%)21 (48.8%)0.133a
 Hypertension43 (89.6%)30 (69.8%)0.018a
 Chronic lung disease13 (27.1%)10 (23.3 %)0.675a
 Number of comorbid diseases
  18 (16.7%)8 (16.7%)0.808a
  232 (66.7%)30 (69.8%)0.751a
  37 (14.6%)5 (11.6%)0.677a
  41 (2.1%)00.341a
 Glucose, mg/dl145 (116–234)172 (137–238)0.061b
 Urea, mg/dl54 (42–71)60 (39–73)0.877b
 Creatine, mg/dl1 (0.81–1.22)1 (0.8–1.38)0.937b
 Sodium, mmol/l137 (133–139)138 (134–142)0.232b
 Potassium, mmol/l3.92 (3.34–4.43)4.2 (3.54–4.6)0.180b
 AST, U/l26 (18–58)27 (23–43)0.946b
 ALT, U/l18 (12–27)18 (15–24)0.696b
 Albumin, g/dl2.77 (2.5–3.2)2.75 (2.53–2.99)0.382b
 CRP, mg/dl7.41 (2.1–12.5)9.9 (3.8–16)0.278b
 D-dimer, ug/l1446 (849–2320)1610 (923–3380)0.373b
 Arterial blood gas analysis
  pH7.39 (7.37–7.45)7.40 (7.33–7.45)0.349b
  pCO2, mmHg39 (32–42)36 (34–45)0.656b
  HCO3, mmol/l24 (22–25)22 (20–25)0.044b
 ONSD, mm4.15 (4.06–4.25)5.95 (5.8–6.25)<0.001b
 APACHE II score8 (8–9)12 (10–15)<0.001b
 SOFA score2 (2–2)3 (3–4)<0.001b
 GCS score15 (15–15)14 (11–15)<0.001b
 PaO2:FiO2 ratio, mmHg227 (200–250)130 (120–160)<0.001b
 IMV9 (19%)32 (74%)<0.001a
 NIV39 (81.3%)11 (25.6%)
 Length of ICU stay, day4 (3–9)8 (6–14)<0.001b
ParametersSurvivor (n = 48)Nonsurvivor (n = 43)P value
Sex
 Male26 (54.2%)24 (55.8%)0.875a
 Female22 (45.8%)19 (44.2%)
Age, years75 (65–84)71 (63–84)0.247b
BMI, kg/m224.6 (23.3–27.8)25.95 (22.8–31.2)0.209b
Comorbid diseases
 Cardiovascular disease26 (54.2%)22 (51.2%)0.774a
 Diabetes mellitus16 (33.3%)21 (48.8%)0.133a
 Hypertension43 (89.6%)30 (69.8%)0.018a
 Chronic lung disease13 (27.1%)10 (23.3 %)0.675a
 Number of comorbid diseases
  18 (16.7%)8 (16.7%)0.808a
  232 (66.7%)30 (69.8%)0.751a
  37 (14.6%)5 (11.6%)0.677a
  41 (2.1%)00.341a
 Glucose, mg/dl145 (116–234)172 (137–238)0.061b
 Urea, mg/dl54 (42–71)60 (39–73)0.877b
 Creatine, mg/dl1 (0.81–1.22)1 (0.8–1.38)0.937b
 Sodium, mmol/l137 (133–139)138 (134–142)0.232b
 Potassium, mmol/l3.92 (3.34–4.43)4.2 (3.54–4.6)0.180b
 AST, U/l26 (18–58)27 (23–43)0.946b
 ALT, U/l18 (12–27)18 (15–24)0.696b
 Albumin, g/dl2.77 (2.5–3.2)2.75 (2.53–2.99)0.382b
 CRP, mg/dl7.41 (2.1–12.5)9.9 (3.8–16)0.278b
 D-dimer, ug/l1446 (849–2320)1610 (923–3380)0.373b
 Arterial blood gas analysis
  pH7.39 (7.37–7.45)7.40 (7.33–7.45)0.349b
  pCO2, mmHg39 (32–42)36 (34–45)0.656b
  HCO3, mmol/l24 (22–25)22 (20–25)0.044b
 ONSD, mm4.15 (4.06–4.25)5.95 (5.8–6.25)<0.001b
 APACHE II score8 (8–9)12 (10–15)<0.001b
 SOFA score2 (2–2)3 (3–4)<0.001b
 GCS score15 (15–15)14 (11–15)<0.001b
 PaO2:FiO2 ratio, mmHg227 (200–250)130 (120–160)<0.001b
 IMV9 (19%)32 (74%)<0.001a
 NIV39 (81.3%)11 (25.6%)
 Length of ICU stay, day4 (3–9)8 (6–14)<0.001b

Categorical data shown as number (percentage). Non-normally distributed continuous variables displayed as median (interquartile range). P < 0.05: significant (shown in bold).

BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CRP, C-reactive protein; pH, potential of hydrogen; PCO2, carbon dioxide arterial partial pressure; HCO3, bicarbonate; ONSD, optic nerve sheath diameter; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; GCS, Glasgow Coma Scale; PaO2:FiO2, arterial blood gas and arterial partial pressure of oxygen:fraction of inspired oxygen; IMV, invasive mechanical ventilation; NIV, non-invasive mechanical ventilation; ICU, intensive care unit.

a

Chi-square test,.

b

Mann–Whitney’s test.

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