Univariate and multivariate Cox analysis for determining factors associated with OPIs
Varaibles . | HR . | 95% CI . | P-value . | HR . | 95% CI . | P-value . |
---|---|---|---|---|---|---|
Age | 1.08 | 1.02–1.14 | .01 | 1.08 | 1.01–1.14 | .02 |
Female | 2.08 | 0.76–5.76 | .15 | |||
ECD | 1.13 | 0.40–3.20 | .82 | |||
eGFR on day 0 | 0.94 | 0.87–1.01 | .09 | 0.94 | 0.86–1.03 | .15 |
Transplant department | 1.15 | 0.41–3.25 | .79 | |||
Interval between biopsy and kidney transplantation | 1.01 | 0.99–1.02 | .14 | |||
Tacrolimus before switch or biopsy | 0.48 | 0.17–1.33 | .16 | |||
MMF before switch or biopsy | 0.87 | 0.24–3.07 | .82 | |||
Steroids before switch or biopsy | 2.12 | 0.60–7.53 | .24 | |||
MMF after switch or biopsy | 1.50 | 0.34–6.67 | .59 | |||
Steroids after switch or biopsy | 1.51 | 0.56–2.23 | .48 | |||
Belatacept switch | 6.31 | 1.42–27.95 | .01 | 4.84 | 1.09–21.51 | .04 |
Rejection after switch or biopsy | 1.50 | 0.34–6.71 | .59 | |||
Cancer after switch or biopsy | 2.48 | 0.79–7.80 | .12 |
Varaibles . | HR . | 95% CI . | P-value . | HR . | 95% CI . | P-value . |
---|---|---|---|---|---|---|
Age | 1.08 | 1.02–1.14 | .01 | 1.08 | 1.01–1.14 | .02 |
Female | 2.08 | 0.76–5.76 | .15 | |||
ECD | 1.13 | 0.40–3.20 | .82 | |||
eGFR on day 0 | 0.94 | 0.87–1.01 | .09 | 0.94 | 0.86–1.03 | .15 |
Transplant department | 1.15 | 0.41–3.25 | .79 | |||
Interval between biopsy and kidney transplantation | 1.01 | 0.99–1.02 | .14 | |||
Tacrolimus before switch or biopsy | 0.48 | 0.17–1.33 | .16 | |||
MMF before switch or biopsy | 0.87 | 0.24–3.07 | .82 | |||
Steroids before switch or biopsy | 2.12 | 0.60–7.53 | .24 | |||
MMF after switch or biopsy | 1.50 | 0.34–6.67 | .59 | |||
Steroids after switch or biopsy | 1.51 | 0.56–2.23 | .48 | |||
Belatacept switch | 6.31 | 1.42–27.95 | .01 | 4.84 | 1.09–21.51 | .04 |
Rejection after switch or biopsy | 1.50 | 0.34–6.71 | .59 | |||
Cancer after switch or biopsy | 2.48 | 0.79–7.80 | .12 |
Bold values are independent risk factors for opportunistic infections. Italicized values are statistically significant result in univariate analysis.
Univariate and multivariate Cox analysis for determining factors associated with OPIs
Varaibles . | HR . | 95% CI . | P-value . | HR . | 95% CI . | P-value . |
---|---|---|---|---|---|---|
Age | 1.08 | 1.02–1.14 | .01 | 1.08 | 1.01–1.14 | .02 |
Female | 2.08 | 0.76–5.76 | .15 | |||
ECD | 1.13 | 0.40–3.20 | .82 | |||
eGFR on day 0 | 0.94 | 0.87–1.01 | .09 | 0.94 | 0.86–1.03 | .15 |
Transplant department | 1.15 | 0.41–3.25 | .79 | |||
Interval between biopsy and kidney transplantation | 1.01 | 0.99–1.02 | .14 | |||
Tacrolimus before switch or biopsy | 0.48 | 0.17–1.33 | .16 | |||
MMF before switch or biopsy | 0.87 | 0.24–3.07 | .82 | |||
Steroids before switch or biopsy | 2.12 | 0.60–7.53 | .24 | |||
MMF after switch or biopsy | 1.50 | 0.34–6.67 | .59 | |||
Steroids after switch or biopsy | 1.51 | 0.56–2.23 | .48 | |||
Belatacept switch | 6.31 | 1.42–27.95 | .01 | 4.84 | 1.09–21.51 | .04 |
Rejection after switch or biopsy | 1.50 | 0.34–6.71 | .59 | |||
Cancer after switch or biopsy | 2.48 | 0.79–7.80 | .12 |
Varaibles . | HR . | 95% CI . | P-value . | HR . | 95% CI . | P-value . |
---|---|---|---|---|---|---|
Age | 1.08 | 1.02–1.14 | .01 | 1.08 | 1.01–1.14 | .02 |
Female | 2.08 | 0.76–5.76 | .15 | |||
ECD | 1.13 | 0.40–3.20 | .82 | |||
eGFR on day 0 | 0.94 | 0.87–1.01 | .09 | 0.94 | 0.86–1.03 | .15 |
Transplant department | 1.15 | 0.41–3.25 | .79 | |||
Interval between biopsy and kidney transplantation | 1.01 | 0.99–1.02 | .14 | |||
Tacrolimus before switch or biopsy | 0.48 | 0.17–1.33 | .16 | |||
MMF before switch or biopsy | 0.87 | 0.24–3.07 | .82 | |||
Steroids before switch or biopsy | 2.12 | 0.60–7.53 | .24 | |||
MMF after switch or biopsy | 1.50 | 0.34–6.67 | .59 | |||
Steroids after switch or biopsy | 1.51 | 0.56–2.23 | .48 | |||
Belatacept switch | 6.31 | 1.42–27.95 | .01 | 4.84 | 1.09–21.51 | .04 |
Rejection after switch or biopsy | 1.50 | 0.34–6.71 | .59 | |||
Cancer after switch or biopsy | 2.48 | 0.79–7.80 | .12 |
Bold values are independent risk factors for opportunistic infections. Italicized values are statistically significant result in univariate analysis.
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