Table 5.

Characteristics of OPIs during the follow-up

CharacteristicsCNI group (n = 70)Belatacept group (n = 69)P-value
Cumulative months of treatment exposure23432200
Pneumocystis pneumonia, n (%)0 (0)4 (5.8).04
Cryptococcus neoformans infection n (%)0 (0)1 (1.4).31
Aspergillosis, n (%)0 (0)1 (1.4).31
Varicella zoster, n (%)1 (1.4)5 (7.2).07
EBV-positive PTLD, n (%)1 (1.4)0.43
CMV disease, n (%)0 (0)3 (4.3).08
Total OPIs, n (%)
OPIs/month of exposure
OPI/100 person-years
2 (2.9)
.0001
1.0
14 (20.3)
.0006
7.6
.0002
OPI related deaths, n (%)1 (1.4)3 (4.3).10
CharacteristicsCNI group (n = 70)Belatacept group (n = 69)P-value
Cumulative months of treatment exposure23432200
Pneumocystis pneumonia, n (%)0 (0)4 (5.8).04
Cryptococcus neoformans infection n (%)0 (0)1 (1.4).31
Aspergillosis, n (%)0 (0)1 (1.4).31
Varicella zoster, n (%)1 (1.4)5 (7.2).07
EBV-positive PTLD, n (%)1 (1.4)0.43
CMV disease, n (%)0 (0)3 (4.3).08
Total OPIs, n (%)
OPIs/month of exposure
OPI/100 person-years
2 (2.9)
.0001
1.0
14 (20.3)
.0006
7.6
.0002
OPI related deaths, n (%)1 (1.4)3 (4.3).10

PTLD: posttransplant lymphoproliferative disease.

Table 5.

Characteristics of OPIs during the follow-up

CharacteristicsCNI group (n = 70)Belatacept group (n = 69)P-value
Cumulative months of treatment exposure23432200
Pneumocystis pneumonia, n (%)0 (0)4 (5.8).04
Cryptococcus neoformans infection n (%)0 (0)1 (1.4).31
Aspergillosis, n (%)0 (0)1 (1.4).31
Varicella zoster, n (%)1 (1.4)5 (7.2).07
EBV-positive PTLD, n (%)1 (1.4)0.43
CMV disease, n (%)0 (0)3 (4.3).08
Total OPIs, n (%)
OPIs/month of exposure
OPI/100 person-years
2 (2.9)
.0001
1.0
14 (20.3)
.0006
7.6
.0002
OPI related deaths, n (%)1 (1.4)3 (4.3).10
CharacteristicsCNI group (n = 70)Belatacept group (n = 69)P-value
Cumulative months of treatment exposure23432200
Pneumocystis pneumonia, n (%)0 (0)4 (5.8).04
Cryptococcus neoformans infection n (%)0 (0)1 (1.4).31
Aspergillosis, n (%)0 (0)1 (1.4).31
Varicella zoster, n (%)1 (1.4)5 (7.2).07
EBV-positive PTLD, n (%)1 (1.4)0.43
CMV disease, n (%)0 (0)3 (4.3).08
Total OPIs, n (%)
OPIs/month of exposure
OPI/100 person-years
2 (2.9)
.0001
1.0
14 (20.3)
.0006
7.6
.0002
OPI related deaths, n (%)1 (1.4)3 (4.3).10

PTLD: posttransplant lymphoproliferative disease.

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