Table 2.

Type of health care and type of interventions per primary outcome category in 518 RCTs conducted in primary care during 2000–2020.

Health care type/intervention typePatient health outcomes, N = 357Health services outcomes, N = 161Unadjusted P-valuea
Health care type
 Preventive care, n (%)77 (21.6)38 (23.6)0.001
 Acute care, n (%)113 (31.7)49 (30.4)
 Chronic care, n (%)162 (45.4)62 (38.5)
 Palliative care, n (%)2 (0.6)0
 Multiple health care types, n (%)b3 (0.8)12 (7.5)
Type of intervention
 Drug/food/device, n (%)142 (39.8)0<0.001
 Behavioural intervention (on patients), n (%)47 (13.2)0
 Intervention on structure, n (%)36 (10.1)51 (31.7)
 Intervention on processes of care, n (%)129 (36.1)110 (68.3)
 Multiple types of intervention, n (%)c3 (0.8)0
Health care type/intervention typePatient health outcomes, N = 357Health services outcomes, N = 161Unadjusted P-valuea
Health care type
 Preventive care, n (%)77 (21.6)38 (23.6)0.001
 Acute care, n (%)113 (31.7)49 (30.4)
 Chronic care, n (%)162 (45.4)62 (38.5)
 Palliative care, n (%)2 (0.6)0
 Multiple health care types, n (%)b3 (0.8)12 (7.5)
Type of intervention
 Drug/food/device, n (%)142 (39.8)0<0.001
 Behavioural intervention (on patients), n (%)47 (13.2)0
 Intervention on structure, n (%)36 (10.1)51 (31.7)
 Intervention on processes of care, n (%)129 (36.1)110 (68.3)
 Multiple types of intervention, n (%)c3 (0.8)0

We considered statistically significant an adjusted threshold of P < 0.003, after applying Bonferroni correction for multiple comparisons.

Multiple health care types: RCTs with patient health outcomes: chronic and acute care (n = 1); chronic and preventive care (n = 2), RCTs with health services outcomes: chronic and acute care (n = 7); chronic and preventive care (n = 3); chronic, acute, and preventive care (n = 2).

Multiple types of intervention: behavioural intervention (on patients) and intervention on structure (n = 1); behavioural intervention (on patients) and a drug (n = 2).

Table 2.

Type of health care and type of interventions per primary outcome category in 518 RCTs conducted in primary care during 2000–2020.

Health care type/intervention typePatient health outcomes, N = 357Health services outcomes, N = 161Unadjusted P-valuea
Health care type
 Preventive care, n (%)77 (21.6)38 (23.6)0.001
 Acute care, n (%)113 (31.7)49 (30.4)
 Chronic care, n (%)162 (45.4)62 (38.5)
 Palliative care, n (%)2 (0.6)0
 Multiple health care types, n (%)b3 (0.8)12 (7.5)
Type of intervention
 Drug/food/device, n (%)142 (39.8)0<0.001
 Behavioural intervention (on patients), n (%)47 (13.2)0
 Intervention on structure, n (%)36 (10.1)51 (31.7)
 Intervention on processes of care, n (%)129 (36.1)110 (68.3)
 Multiple types of intervention, n (%)c3 (0.8)0
Health care type/intervention typePatient health outcomes, N = 357Health services outcomes, N = 161Unadjusted P-valuea
Health care type
 Preventive care, n (%)77 (21.6)38 (23.6)0.001
 Acute care, n (%)113 (31.7)49 (30.4)
 Chronic care, n (%)162 (45.4)62 (38.5)
 Palliative care, n (%)2 (0.6)0
 Multiple health care types, n (%)b3 (0.8)12 (7.5)
Type of intervention
 Drug/food/device, n (%)142 (39.8)0<0.001
 Behavioural intervention (on patients), n (%)47 (13.2)0
 Intervention on structure, n (%)36 (10.1)51 (31.7)
 Intervention on processes of care, n (%)129 (36.1)110 (68.3)
 Multiple types of intervention, n (%)c3 (0.8)0

We considered statistically significant an adjusted threshold of P < 0.003, after applying Bonferroni correction for multiple comparisons.

Multiple health care types: RCTs with patient health outcomes: chronic and acute care (n = 1); chronic and preventive care (n = 2), RCTs with health services outcomes: chronic and acute care (n = 7); chronic and preventive care (n = 3); chronic, acute, and preventive care (n = 2).

Multiple types of intervention: behavioural intervention (on patients) and intervention on structure (n = 1); behavioural intervention (on patients) and a drug (n = 2).

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