Table 2
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Sixteen proteins were significant different between Healthy Controls, PMS and RRMS in both discovery and replication cohort (ANOVA q < 0.01)

ProteinDiscovery P-valueDiscovery q-valueReplication P-valueReplication q-value
CCL31.7E-186.7E-172.4E-168.2E-15
IL-12B2.6E-186.7E-172.0E-092.2E-08
CD52.4E-144.1E-136.0E-101.0E-08
IL81.5E-132.0E-128.3E-073.5E-06
CXCL102.8E-122.8E-116.1E-095.1E-08
CXCL111.8E-111.5E-108.0E-084.5E-07
CXCL15.1E-113.7E-102.1E-068.1E-06
CXCL99.1E-115.8E-101.5E-081.0E-07
TNFRSF93.6E-102.1E-091.4E-043.6E-04
TNFSF148.8E-084.5E-073.7E-071.8E-06
CD8A1.4E-076.3E-078.8E-042.0E-03
CCL41.7E-077.3E-071.0E-042.9E-04
MCP-25.1E-072.0E-061.2E-054.2E-05
CCL238.8E-063.2E-056.3E-041.5E-03
IL184.1E-051.2E-043.3E-037.1E-03
CCL191.6E-043.9E-042.6E-057.9E-05
ProteinDiscovery P-valueDiscovery q-valueReplication P-valueReplication q-value
CCL31.7E-186.7E-172.4E-168.2E-15
IL-12B2.6E-186.7E-172.0E-092.2E-08
CD52.4E-144.1E-136.0E-101.0E-08
IL81.5E-132.0E-128.3E-073.5E-06
CXCL102.8E-122.8E-116.1E-095.1E-08
CXCL111.8E-111.5E-108.0E-084.5E-07
CXCL15.1E-113.7E-102.1E-068.1E-06
CXCL99.1E-115.8E-101.5E-081.0E-07
TNFRSF93.6E-102.1E-091.4E-043.6E-04
TNFSF148.8E-084.5E-073.7E-071.8E-06
CD8A1.4E-076.3E-078.8E-042.0E-03
CCL41.7E-077.3E-071.0E-042.9E-04
MCP-25.1E-072.0E-061.2E-054.2E-05
CCL238.8E-063.2E-056.3E-041.5E-03
IL184.1E-051.2E-043.3E-037.1E-03
CCL191.6E-043.9E-042.6E-057.9E-05
Table 2
Open in new tab

Sixteen proteins were significant different between Healthy Controls, PMS and RRMS in both discovery and replication cohort (ANOVA q < 0.01)

ProteinDiscovery P-valueDiscovery q-valueReplication P-valueReplication q-value
CCL31.7E-186.7E-172.4E-168.2E-15
IL-12B2.6E-186.7E-172.0E-092.2E-08
CD52.4E-144.1E-136.0E-101.0E-08
IL81.5E-132.0E-128.3E-073.5E-06
CXCL102.8E-122.8E-116.1E-095.1E-08
CXCL111.8E-111.5E-108.0E-084.5E-07
CXCL15.1E-113.7E-102.1E-068.1E-06
CXCL99.1E-115.8E-101.5E-081.0E-07
TNFRSF93.6E-102.1E-091.4E-043.6E-04
TNFSF148.8E-084.5E-073.7E-071.8E-06
CD8A1.4E-076.3E-078.8E-042.0E-03
CCL41.7E-077.3E-071.0E-042.9E-04
MCP-25.1E-072.0E-061.2E-054.2E-05
CCL238.8E-063.2E-056.3E-041.5E-03
IL184.1E-051.2E-043.3E-037.1E-03
CCL191.6E-043.9E-042.6E-057.9E-05
ProteinDiscovery P-valueDiscovery q-valueReplication P-valueReplication q-value
CCL31.7E-186.7E-172.4E-168.2E-15
IL-12B2.6E-186.7E-172.0E-092.2E-08
CD52.4E-144.1E-136.0E-101.0E-08
IL81.5E-132.0E-128.3E-073.5E-06
CXCL102.8E-122.8E-116.1E-095.1E-08
CXCL111.8E-111.5E-108.0E-084.5E-07
CXCL15.1E-113.7E-102.1E-068.1E-06
CXCL99.1E-115.8E-101.5E-081.0E-07
TNFRSF93.6E-102.1E-091.4E-043.6E-04
TNFSF148.8E-084.5E-073.7E-071.8E-06
CD8A1.4E-076.3E-078.8E-042.0E-03
CCL41.7E-077.3E-071.0E-042.9E-04
MCP-25.1E-072.0E-061.2E-054.2E-05
CCL238.8E-063.2E-056.3E-041.5E-03
IL184.1E-051.2E-043.3E-037.1E-03
CCL191.6E-043.9E-042.6E-057.9E-05
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