Table 2

Comparison of A/T groups on neuropsychological z-scores and ECog questionnaire domain scores

VariableA−/T−A−/T+A+/T−A+/T+Test statisticP-value
Diagnosis, % MCI22.0%23.3%29.5%50.8%dχ2 = 39.3<0.001
AVLT recall, mean (SD)−0.3 (1.1)−0.6 (1.2)a−0.6 (1.0)−1.2 (1.1)dF = 19.5<0.001
AVLT recognition, mean (SD)−0.4 (1.2)−0.5 (1.3)−0.6 (1.4)−1.9 (1.9)dF = 25.2<0.001
Naming, mean (SD)0.0 (1.1)−0.4 (1.5)a−0.4 (1.4)−1.1 (2.4)dF = 10.0<0.001
Animal fluency, mean (SD)−0.1 (1.0)−0.3 (1.1)−0.2 (1.1)−0.8 (1.2)dF = 11.3<0.001
TMT A, mean (SD)−0.1 (1.1)−0.1 (1.0)−0.3 (1.4)−1.1 (2.5)dF = 8.9<0.001
TMT B, mean (SD)−0.1 (1.2)−0.2 (1.2)−0.6 (1.8)a−1.5 (2.4)dF = 17.8<0.001
ECog memory, mean (SD)1.8 (0.7)1.9 (0.7)2.0 (0.8)b2.4 (0.9)dF = 14.0<0.001
ECog language, mean (SD)1.6 (0.6)1.6 (0.7)1.8 (0.6)a1.9 (1.0)cF = 6.1<0.001
ECog executive, mean (SD)1.5 (0.6)1.5 (0.6)1.6 (0.5)1.9 (1.0)dF = 8.8<0.001
VariableA−/T−A−/T+A+/T−A+/T+Test statisticP-value
Diagnosis, % MCI22.0%23.3%29.5%50.8%dχ2 = 39.3<0.001
AVLT recall, mean (SD)−0.3 (1.1)−0.6 (1.2)a−0.6 (1.0)−1.2 (1.1)dF = 19.5<0.001
AVLT recognition, mean (SD)−0.4 (1.2)−0.5 (1.3)−0.6 (1.4)−1.9 (1.9)dF = 25.2<0.001
Naming, mean (SD)0.0 (1.1)−0.4 (1.5)a−0.4 (1.4)−1.1 (2.4)dF = 10.0<0.001
Animal fluency, mean (SD)−0.1 (1.0)−0.3 (1.1)−0.2 (1.1)−0.8 (1.2)dF = 11.3<0.001
TMT A, mean (SD)−0.1 (1.1)−0.1 (1.0)−0.3 (1.4)−1.1 (2.5)dF = 8.9<0.001
TMT B, mean (SD)−0.1 (1.2)−0.2 (1.2)−0.6 (1.8)a−1.5 (2.4)dF = 17.8<0.001
ECog memory, mean (SD)1.8 (0.7)1.9 (0.7)2.0 (0.8)b2.4 (0.9)dF = 14.0<0.001
ECog language, mean (SD)1.6 (0.6)1.6 (0.7)1.8 (0.6)a1.9 (1.0)cF = 6.1<0.001
ECog executive, mean (SD)1.5 (0.6)1.5 (0.6)1.6 (0.5)1.9 (1.0)dF = 8.8<0.001

AVLT, auditory verbal learning test; TMT, trail making test; SD, standard deviation. Note that the values reported here do not reflect the transformed and residualized values used in model estimates.

a

Significantly different from the A−/T− group.

b

Significantly different from the A−/T + group.

c

Significantly different from the A−/T− and A−/T+ groups.

d

Significantly different from all other groups.

Table 2

Comparison of A/T groups on neuropsychological z-scores and ECog questionnaire domain scores

VariableA−/T−A−/T+A+/T−A+/T+Test statisticP-value
Diagnosis, % MCI22.0%23.3%29.5%50.8%dχ2 = 39.3<0.001
AVLT recall, mean (SD)−0.3 (1.1)−0.6 (1.2)a−0.6 (1.0)−1.2 (1.1)dF = 19.5<0.001
AVLT recognition, mean (SD)−0.4 (1.2)−0.5 (1.3)−0.6 (1.4)−1.9 (1.9)dF = 25.2<0.001
Naming, mean (SD)0.0 (1.1)−0.4 (1.5)a−0.4 (1.4)−1.1 (2.4)dF = 10.0<0.001
Animal fluency, mean (SD)−0.1 (1.0)−0.3 (1.1)−0.2 (1.1)−0.8 (1.2)dF = 11.3<0.001
TMT A, mean (SD)−0.1 (1.1)−0.1 (1.0)−0.3 (1.4)−1.1 (2.5)dF = 8.9<0.001
TMT B, mean (SD)−0.1 (1.2)−0.2 (1.2)−0.6 (1.8)a−1.5 (2.4)dF = 17.8<0.001
ECog memory, mean (SD)1.8 (0.7)1.9 (0.7)2.0 (0.8)b2.4 (0.9)dF = 14.0<0.001
ECog language, mean (SD)1.6 (0.6)1.6 (0.7)1.8 (0.6)a1.9 (1.0)cF = 6.1<0.001
ECog executive, mean (SD)1.5 (0.6)1.5 (0.6)1.6 (0.5)1.9 (1.0)dF = 8.8<0.001
VariableA−/T−A−/T+A+/T−A+/T+Test statisticP-value
Diagnosis, % MCI22.0%23.3%29.5%50.8%dχ2 = 39.3<0.001
AVLT recall, mean (SD)−0.3 (1.1)−0.6 (1.2)a−0.6 (1.0)−1.2 (1.1)dF = 19.5<0.001
AVLT recognition, mean (SD)−0.4 (1.2)−0.5 (1.3)−0.6 (1.4)−1.9 (1.9)dF = 25.2<0.001
Naming, mean (SD)0.0 (1.1)−0.4 (1.5)a−0.4 (1.4)−1.1 (2.4)dF = 10.0<0.001
Animal fluency, mean (SD)−0.1 (1.0)−0.3 (1.1)−0.2 (1.1)−0.8 (1.2)dF = 11.3<0.001
TMT A, mean (SD)−0.1 (1.1)−0.1 (1.0)−0.3 (1.4)−1.1 (2.5)dF = 8.9<0.001
TMT B, mean (SD)−0.1 (1.2)−0.2 (1.2)−0.6 (1.8)a−1.5 (2.4)dF = 17.8<0.001
ECog memory, mean (SD)1.8 (0.7)1.9 (0.7)2.0 (0.8)b2.4 (0.9)dF = 14.0<0.001
ECog language, mean (SD)1.6 (0.6)1.6 (0.7)1.8 (0.6)a1.9 (1.0)cF = 6.1<0.001
ECog executive, mean (SD)1.5 (0.6)1.5 (0.6)1.6 (0.5)1.9 (1.0)dF = 8.8<0.001

AVLT, auditory verbal learning test; TMT, trail making test; SD, standard deviation. Note that the values reported here do not reflect the transformed and residualized values used in model estimates.

a

Significantly different from the A−/T− group.

b

Significantly different from the A−/T + group.

c

Significantly different from the A−/T− and A−/T+ groups.

d

Significantly different from all other groups.

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