Table 3.

Analysis of adverse events.

Adverse eventsWith nituzumab
(n = 39)
Without nituzumab
(n = 17)
χ2P
Grades 1-2 (n, %)Grades 1-2 (n, %)
Leukopenia20(51.3)8(47.1)0.084.771
Neutropenia13(33.3)5(29.4)0.083.773
Thrombocytopenia9(23.1)4(23.5)0.0001.000
Fever1(2.6)0(0)1.000
Dizziness1(2.6)0(0)1.000
Vomiting4(10.3)5(29.4)1.957.162
Rash4(10.3)0(0)0.650.420
Fatigue2(5.1)0(0)0.044.834
Constipation2(5.1)0(0)0.044.834
ALT/AST elevation1(2.6)1(5.9)0.0001.000
Adverse eventsWith nituzumab
(n = 39)
Without nituzumab
(n = 17)
χ2P
Grades 1-2 (n, %)Grades 1-2 (n, %)
Leukopenia20(51.3)8(47.1)0.084.771
Neutropenia13(33.3)5(29.4)0.083.773
Thrombocytopenia9(23.1)4(23.5)0.0001.000
Fever1(2.6)0(0)1.000
Dizziness1(2.6)0(0)1.000
Vomiting4(10.3)5(29.4)1.957.162
Rash4(10.3)0(0)0.650.420
Fatigue2(5.1)0(0)0.044.834
Constipation2(5.1)0(0)0.044.834
ALT/AST elevation1(2.6)1(5.9)0.0001.000

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.

Table 3.

Analysis of adverse events.

Adverse eventsWith nituzumab
(n = 39)
Without nituzumab
(n = 17)
χ2P
Grades 1-2 (n, %)Grades 1-2 (n, %)
Leukopenia20(51.3)8(47.1)0.084.771
Neutropenia13(33.3)5(29.4)0.083.773
Thrombocytopenia9(23.1)4(23.5)0.0001.000
Fever1(2.6)0(0)1.000
Dizziness1(2.6)0(0)1.000
Vomiting4(10.3)5(29.4)1.957.162
Rash4(10.3)0(0)0.650.420
Fatigue2(5.1)0(0)0.044.834
Constipation2(5.1)0(0)0.044.834
ALT/AST elevation1(2.6)1(5.9)0.0001.000
Adverse eventsWith nituzumab
(n = 39)
Without nituzumab
(n = 17)
χ2P
Grades 1-2 (n, %)Grades 1-2 (n, %)
Leukopenia20(51.3)8(47.1)0.084.771
Neutropenia13(33.3)5(29.4)0.083.773
Thrombocytopenia9(23.1)4(23.5)0.0001.000
Fever1(2.6)0(0)1.000
Dizziness1(2.6)0(0)1.000
Vomiting4(10.3)5(29.4)1.957.162
Rash4(10.3)0(0)0.650.420
Fatigue2(5.1)0(0)0.044.834
Constipation2(5.1)0(0)0.044.834
ALT/AST elevation1(2.6)1(5.9)0.0001.000

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.

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