Table 3. Open in new tab Mortality Rates...

4C Mortality Score Risk Group	Epidemiological Wave Period	Overall	United Kingdom
All 4C score	3.1%^a (128/4162)	.64%^a (46/7241)	1.7%^a (222/13 009)	1.8%^a (107/5876)	1.4%^a (92/6671)	0%^a (0/643)	1.6%^a (595/37 602)	31.3% (18 155/57 924)
Low (0–3)	.13%^a (3/2240)	0%^a (0/4816)	.14%^a (8/6114)	.11%^a (3/2665)	.051%^a (2/3955)	0%^b (0/386)	.079%^a (16/20 176)	1.5% (65/4224)
Intermediate (4–8)	2.8%^a (41/1482)	.86%^a (17/1979)	1.4%^a (76/5424)	1.6%^a (40/2521)	1.7%^a (40/2351)	0%^a (0/220)	1.5%^a (214/13 977)	9.4% (1237/13 166)
High (9–14)	19%^a (81/428)	6.2%^a (27/436)	8.8%^a (126/1439)	8.8%^a (60/680)	13%^a (46/358)	0%^a (0/37)	10%^a (340/3378)	34% (9976/29 755)
Very high (15–21)	25%^a (3/12)	20%^a (2/10)	38%^a (12/32)	40% (4/10)	57% (4/7)	0/0	35%^a (25/71)	6877/10 679 (64%)

4C Mortality Score Risk Group	Epidemiological Wave Period	Overall	United Kingdom
All 4C score	3.1%^a (128/4162)	.64%^a (46/7241)	1.7%^a (222/13 009)	1.8%^a (107/5876)	1.4%^a (92/6671)	0%^a (0/643)	1.6%^a (595/37 602)	31.3% (18 155/57 924)
Low (0–3)	.13%^a (3/2240)	0%^a (0/4816)	.14%^a (8/6114)	.11%^a (3/2665)	.051%^a (2/3955)	0%^b (0/386)	.079%^a (16/20 176)	1.5% (65/4224)
Intermediate (4–8)	2.8%^a (41/1482)	.86%^a (17/1979)	1.4%^a (76/5424)	1.6%^a (40/2521)	1.7%^a (40/2351)	0%^a (0/220)	1.5%^a (214/13 977)	9.4% (1237/13 166)
High (9–14)	19%^a (81/428)	6.2%^a (27/436)	8.8%^a (126/1439)	8.8%^a (60/680)	13%^a (46/358)	0%^a (0/37)	10%^a (340/3378)	34% (9976/29 755)
Very high (15–21)	25%^a (3/12)	20%^a (2/10)	38%^a (12/32)	40% (4/10)	57% (4/7)	0/0	35%^a (25/71)	6877/10 679 (64%)

Table 3.

Mortality Rates of Patients With Coronavirus Disease 2019 by Epidemiological Wave Period, Stratified by 4C Mortality Score Risk Group in Patients Aged <75 Years

4C Mortality Score Risk Group	Epidemiological Wave Period						Overall	United Kingdom
4C Mortality Score Risk Group	First	Second	Third	Fourth	Fifth	Sixth	Overall	United Kingdom
All 4C score	3.1%^a (128/4162)	.64%^a (46/7241)	1.7%^a (222/13 009)	1.8%^a (107/5876)	1.4%^a (92/6671)	0%^a (0/643)	1.6%^a (595/37 602)	31.3% (18 155/57 924)
Low (0–3)	.13%^a (3/2240)	0%^a (0/4816)	.14%^a (8/6114)	.11%^a (3/2665)	.051%^a (2/3955)	0%^b (0/386)	.079%^a (16/20 176)	1.5% (65/4224)
Intermediate (4–8)	2.8%^a (41/1482)	.86%^a (17/1979)	1.4%^a (76/5424)	1.6%^a (40/2521)	1.7%^a (40/2351)	0%^a (0/220)	1.5%^a (214/13 977)	9.4% (1237/13 166)
High (9–14)	19%^a (81/428)	6.2%^a (27/436)	8.8%^a (126/1439)	8.8%^a (60/680)	13%^a (46/358)	0%^a (0/37)	10%^a (340/3378)	34% (9976/29 755)
Very high (15–21)	25%^a (3/12)	20%^a (2/10)	38%^a (12/32)	40% (4/10)	57% (4/7)	0/0	35%^a (25/71)	6877/10 679 (64%)

4C Mortality Score Risk Group	Epidemiological Wave Period						Overall	United Kingdom
4C Mortality Score Risk Group	First	Second	Third	Fourth	Fifth	Sixth	Overall	United Kingdom
All 4C score	3.1%^a (128/4162)	.64%^a (46/7241)	1.7%^a (222/13 009)	1.8%^a (107/5876)	1.4%^a (92/6671)	0%^a (0/643)	1.6%^a (595/37 602)	31.3% (18 155/57 924)
Low (0–3)	.13%^a (3/2240)	0%^a (0/4816)	.14%^a (8/6114)	.11%^a (3/2665)	.051%^a (2/3955)	0%^b (0/386)	.079%^a (16/20 176)	1.5% (65/4224)
Intermediate (4–8)	2.8%^a (41/1482)	.86%^a (17/1979)	1.4%^a (76/5424)	1.6%^a (40/2521)	1.7%^a (40/2351)	0%^a (0/220)	1.5%^a (214/13 977)	9.4% (1237/13 166)
High (9–14)	19%^a (81/428)	6.2%^a (27/436)	8.8%^a (126/1439)	8.8%^a (60/680)	13%^a (46/358)	0%^a (0/37)	10%^a (340/3378)	34% (9976/29 755)
Very high (15–21)	25%^a (3/12)	20%^a (2/10)	38%^a (12/32)	40% (4/10)	57% (4/7)	0/0	35%^a (25/71)	6877/10 679 (64%)

Numbers indicate number of deaths/total number of patients (%). P values were assessed by χ² test compared with the reported data from the United Kingdom.

Abbreviation: 4C, Coronavirus Clinical Characterisation Consortium.

P < .01.

P < .05.

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