| Hormone . | Tmax (d), median (range) . | Cmax (ng/dL), mean (%CV) . | Cavg (ng/dL), mean (SD) . | AUC0-tlast (ng/dL/d), mean (%CV) . | ||
|---|---|---|---|---|---|---|
| Days 1–113 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | |
| Serum total testosterone | 13.5 (2–32) | 1,021.6 (24.9) | 703.8 (140.9) | 638.3 (124.2) | 59,927.6 (20.9) | 71,720.5 (19.9) |
| DHT | 26 (2–84) | 38.1 (18.0) | 29.9 (14.4) | 28.2 (13.7) | 2,566.5 (51.2) | 3,167.5 (49.6) |
| Free testosterone | 14 (2–53) | 327.6 (79.4) | 212.6 (47.5) | 190.3 (40.8) | 18,128.0 (25.6) | 20,979.4 (24.2) |
| Estradiol | 27 (2–84) | 57.0 (20.1) | 40.3 (17.5) | 36.6 (15.2) | 3,426.8 (36.7) | 4,110.4 (35.9) |
| Hormone . | Tmax (d), median (range) . | Cmax (ng/dL), mean (%CV) . | Cavg (ng/dL), mean (SD) . | AUC0-tlast (ng/dL/d), mean (%CV) . | ||
|---|---|---|---|---|---|---|
| Days 1–113 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | |
| Serum total testosterone | 13.5 (2–32) | 1,021.6 (24.9) | 703.8 (140.9) | 638.3 (124.2) | 59,927.6 (20.9) | 71,720.5 (19.9) |
| DHT | 26 (2–84) | 38.1 (18.0) | 29.9 (14.4) | 28.2 (13.7) | 2,566.5 (51.2) | 3,167.5 (49.6) |
| Free testosterone | 14 (2–53) | 327.6 (79.4) | 212.6 (47.5) | 190.3 (40.8) | 18,128.0 (25.6) | 20,979.4 (24.2) |
| Estradiol | 27 (2–84) | 57.0 (20.1) | 40.3 (17.5) | 36.6 (15.2) | 3,426.8 (36.7) | 4,110.4 (35.9) |
AUC0-tlast = area under the plasma concentration time curve from time 0 to last measurable concentration; %CV = percentage of coefficient of variation; Cavg = average plasma concentration; Cmax = maximum plasma concentration; DHT = dihydrotestosterone; Tmax = time to maximum plasma concentration.
| Hormone . | Tmax (d), median (range) . | Cmax (ng/dL), mean (%CV) . | Cavg (ng/dL), mean (SD) . | AUC0-tlast (ng/dL/d), mean (%CV) . | ||
|---|---|---|---|---|---|---|
| Days 1–113 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | |
| Serum total testosterone | 13.5 (2–32) | 1,021.6 (24.9) | 703.8 (140.9) | 638.3 (124.2) | 59,927.6 (20.9) | 71,720.5 (19.9) |
| DHT | 26 (2–84) | 38.1 (18.0) | 29.9 (14.4) | 28.2 (13.7) | 2,566.5 (51.2) | 3,167.5 (49.6) |
| Free testosterone | 14 (2–53) | 327.6 (79.4) | 212.6 (47.5) | 190.3 (40.8) | 18,128.0 (25.6) | 20,979.4 (24.2) |
| Estradiol | 27 (2–84) | 57.0 (20.1) | 40.3 (17.5) | 36.6 (15.2) | 3,426.8 (36.7) | 4,110.4 (35.9) |
| Hormone . | Tmax (d), median (range) . | Cmax (ng/dL), mean (%CV) . | Cavg (ng/dL), mean (SD) . | AUC0-tlast (ng/dL/d), mean (%CV) . | ||
|---|---|---|---|---|---|---|
| Days 1–113 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | Days 1–85 . | Days 1–113 . | |
| Serum total testosterone | 13.5 (2–32) | 1,021.6 (24.9) | 703.8 (140.9) | 638.3 (124.2) | 59,927.6 (20.9) | 71,720.5 (19.9) |
| DHT | 26 (2–84) | 38.1 (18.0) | 29.9 (14.4) | 28.2 (13.7) | 2,566.5 (51.2) | 3,167.5 (49.6) |
| Free testosterone | 14 (2–53) | 327.6 (79.4) | 212.6 (47.5) | 190.3 (40.8) | 18,128.0 (25.6) | 20,979.4 (24.2) |
| Estradiol | 27 (2–84) | 57.0 (20.1) | 40.3 (17.5) | 36.6 (15.2) | 3,426.8 (36.7) | 4,110.4 (35.9) |
AUC0-tlast = area under the plasma concentration time curve from time 0 to last measurable concentration; %CV = percentage of coefficient of variation; Cavg = average plasma concentration; Cmax = maximum plasma concentration; DHT = dihydrotestosterone; Tmax = time to maximum plasma concentration.
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