Open in new tab Recommendations—benefits...

Recommendations—benefits and risks of T therapy	LoE	Grade
Beyond 6 mo there is evidence of benefit for T therapy in body composition, bone mineralization, and features of metabolic syndrome	3	A
T therapy improves sexual desire, erectile function, and sexual satisfaction	1	A
Decreases in BMI and waist size and improved glycemic control and lipid profile are observed in hypogonadal men receiving T therapy	2	A
Trials of T therapy should be ≥6 mo and maximal benefit is often seen beyond 12 mo	2	A
Fully inform the patient about expected benefits and side effects of therapy and facilitate a joint decision by an informed patient and physician	3	A
Fully discuss the adverse effect of T therapy and its future reversibility on future fertility for each patient and his partner and offer alternative treatment as necessary	1b	B
In patients with adult-onset TD, when T replacement therapy is prescribed, offer weight-loss and lifestyle advice as standard management	2	A
In severely symptomatic patients with TT levels < 8 nmol/L, lifestyle and dietary advice alone is unlikely to produce meaningful clinical improvement within a relevant clinical period	2	B

Recommendations—benefits and risks of T therapy	LoE	Grade
Beyond 6 mo there is evidence of benefit for T therapy in body composition, bone mineralization, and features of metabolic syndrome	3	A
T therapy improves sexual desire, erectile function, and sexual satisfaction	1	A
Decreases in BMI and waist size and improved glycemic control and lipid profile are observed in hypogonadal men receiving T therapy	2	A
Trials of T therapy should be ≥6 mo and maximal benefit is often seen beyond 12 mo	2	A
Fully inform the patient about expected benefits and side effects of therapy and facilitate a joint decision by an informed patient and physician	3	A
Fully discuss the adverse effect of T therapy and its future reversibility on future fertility for each patient and his partner and offer alternative treatment as necessary	1b	B
In patients with adult-onset TD, when T replacement therapy is prescribed, offer weight-loss and lifestyle advice as standard management	2	A
In severely symptomatic patients with TT levels < 8 nmol/L, lifestyle and dietary advice alone is unlikely to produce meaningful clinical improvement within a relevant clinical period	2	B