Recommendations—diagnosisLoEGrade
Restrict diagnosis of TD to men with persistent symptoms suggesting TD and confirmed low T3C
Measure fasting T levels in the morning before 11 am, acknowledging that, in normal life, non-fasting levels could be up to 30% lower2A
Repeat TT assessment on ≥2 occasions by a reliable method; in addition, measure FT in men with levels close to the lower normal range (8–12 nmol/L) or those with suspected or known abnormal SHBG levels1A
Measure LH serum levels to differentiate primary from secondary TD2A
Base decisions on therapy on published action levels rather than laboratory reference ranges4B
Recommendations—diagnosisLoEGrade
Restrict diagnosis of TD to men with persistent symptoms suggesting TD and confirmed low T3C
Measure fasting T levels in the morning before 11 am, acknowledging that, in normal life, non-fasting levels could be up to 30% lower2A
Repeat TT assessment on ≥2 occasions by a reliable method; in addition, measure FT in men with levels close to the lower normal range (8–12 nmol/L) or those with suspected or known abnormal SHBG levels1A
Measure LH serum levels to differentiate primary from secondary TD2A
Base decisions on therapy on published action levels rather than laboratory reference ranges4B
Recommendations—diagnosisLoEGrade
Restrict diagnosis of TD to men with persistent symptoms suggesting TD and confirmed low T3C
Measure fasting T levels in the morning before 11 am, acknowledging that, in normal life, non-fasting levels could be up to 30% lower2A
Repeat TT assessment on ≥2 occasions by a reliable method; in addition, measure FT in men with levels close to the lower normal range (8–12 nmol/L) or those with suspected or known abnormal SHBG levels1A
Measure LH serum levels to differentiate primary from secondary TD2A
Base decisions on therapy on published action levels rather than laboratory reference ranges4B
Recommendations—diagnosisLoEGrade
Restrict diagnosis of TD to men with persistent symptoms suggesting TD and confirmed low T3C
Measure fasting T levels in the morning before 11 am, acknowledging that, in normal life, non-fasting levels could be up to 30% lower2A
Repeat TT assessment on ≥2 occasions by a reliable method; in addition, measure FT in men with levels close to the lower normal range (8–12 nmol/L) or those with suspected or known abnormal SHBG levels1A
Measure LH serum levels to differentiate primary from secondary TD2A
Base decisions on therapy on published action levels rather than laboratory reference ranges4B
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