| Production and Characterization of PEP Specimens | PEP Specimen QC |
| • All specimens generated under strict conditions and rigorously characterized. | • Acceptance criteria: Pure and Potent |
| • Infectious agents are obtained from known sources and sequenced to confirm identity. | • Immune serum |
| − Seropositive to inoculated pathogen only | |
| − Moderate to strong reaction by standard assays | |
| • Experimental animals are inoculated, and the serum and relevant tissues are collected and aliquoted for use as standardized specimens. | • Infectious specimen |
| − Free of extraneous pathogens | |
| − Easily detectable concentration of pathogen | |
| • Aliquoted specimens are evaluated by 2 laboratories to confirm quality |
| Production and Characterization of PEP Specimens | PEP Specimen QC |
| • All specimens generated under strict conditions and rigorously characterized. | • Acceptance criteria: Pure and Potent |
| • Infectious agents are obtained from known sources and sequenced to confirm identity. | • Immune serum |
| − Seropositive to inoculated pathogen only | |
| − Moderate to strong reaction by standard assays | |
| • Experimental animals are inoculated, and the serum and relevant tissues are collected and aliquoted for use as standardized specimens. | • Infectious specimen |
| − Free of extraneous pathogens | |
| − Easily detectable concentration of pathogen | |
| • Aliquoted specimens are evaluated by 2 laboratories to confirm quality |
PEP, Performance Evaluation Program; QC, quality control.
| Production and Characterization of PEP Specimens | PEP Specimen QC |
| • All specimens generated under strict conditions and rigorously characterized. | • Acceptance criteria: Pure and Potent |
| • Infectious agents are obtained from known sources and sequenced to confirm identity. | • Immune serum |
| − Seropositive to inoculated pathogen only | |
| − Moderate to strong reaction by standard assays | |
| • Experimental animals are inoculated, and the serum and relevant tissues are collected and aliquoted for use as standardized specimens. | • Infectious specimen |
| − Free of extraneous pathogens | |
| − Easily detectable concentration of pathogen | |
| • Aliquoted specimens are evaluated by 2 laboratories to confirm quality |
| Production and Characterization of PEP Specimens | PEP Specimen QC |
| • All specimens generated under strict conditions and rigorously characterized. | • Acceptance criteria: Pure and Potent |
| • Infectious agents are obtained from known sources and sequenced to confirm identity. | • Immune serum |
| − Seropositive to inoculated pathogen only | |
| − Moderate to strong reaction by standard assays | |
| • Experimental animals are inoculated, and the serum and relevant tissues are collected and aliquoted for use as standardized specimens. | • Infectious specimen |
| − Free of extraneous pathogens | |
| − Easily detectable concentration of pathogen | |
| • Aliquoted specimens are evaluated by 2 laboratories to confirm quality |
PEP, Performance Evaluation Program; QC, quality control.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
