Table 1 Open in new tab Characteristics...

	Number of non-ideal Life’s Simple 7
The number of non-ideal cardiovascular health components
0, n (%)	2 913 (22.1)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	<0.001
1, n (%)	10 245 (77.9)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
2, n (%)	0 (0)	14 968 (100)	0 (0)	0 (0)	0 (0)	0 (0)
3, n (%)	0 (0)	0 (0)	13 097 (100)	0 (0)	0 (0)	0 (0)
4, n (%)	0 (0)	0 (0)	0 (0)	8 247 (100)	0 (0)	0 (0)
5, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	3,553 (100)	0 (0)
6, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	851 (89.5)
7, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	100 (10.5)
Non-ideal body mass index, n (%)	145 (1.1)	1013 (6.8)	2767 (21.1)	4001 (48.5)	2677 (75.3)	821 (86.3)	<0.001
Non-ideal smoking, n (%)	235 (1.8)	1064 (7.1)	1753 (13.4)	1976 (24.0)	1273 (35.8)	699 (73.5)	<0.001
Non-ideal physical activity, n (%)	3405 (25.9)	7342 (49.1)	7798 (59.5)	5913 (71.7)	3062 (86.2)	886 (93.2)	<0.001
Non-ideal eating habit, n (%)	264 (2.0)	1,072 (7.2)	1,699 (13.0)	1,644 (19.9)	1,148 (32.3)	670 (70.5)	<0.001
Non-ideal blood pressure, n (%)	2026 (15.4)	7677 (51.3)	10 196 (77.8)	7329 (88.9)	3376 (95.0)	932 (98.0)	<0.001
Non-ideal fasting glucose, n (%)	434 (3.3)	2302 (15.4)	5003 (38.2)	5208 (63.2)	2936 (82.6)	872 (91.7)	<0.001
Non-ideal total cholesterol, n (%)	3,736 (28.4)	9,466 (63.2)	10,075 (76.9)	6,917 (83.9)	3,293 (92.7)	926 (97.4)	<0.001
Age, years	50 (45–56)	54 (48–60)	56 (50–62)	57 (51–62)	56 (51–62)	55 (50–60)	<0.001
Men, n (%)	2836 (21.6)	4722 (31.5)	5523 (42.2)	4377 (53.1)	2202 (62.0)	726 (76.3)	<0.001
Body mass index, kg/m²	20.3 (18.8–21.9)	21.2 (19.4–23)	22.5 (20.4–24.5)	24.8 (22–27)	26.4 (25–28.7)	27.1 (25.5–29.3)	<0.001
Systolic blood pressure, mmHg	108 (100–115)	117 (107–128)	125 (116–135)	128 (120–138)	130 (123–140)	131 (123–140)	<0.001
Diastolic blood pressure, mmHg	67 (61–73)	73 (66–81)	78 (70–84)	80 (73–87)	82 (76–89)	83 (77–89)	<0.001
Glucose, mg/dL	89 (84–94)	91.5 (86–97)	96 (89–104)	102 (94–111)	106 (101–118)	109 (103–123)	<0.001
Total cholesterol, mg/dL	187 (170–204)	208 (186–231)	215 (194–239)	216 (197–238)	218 (201–242)	218.5 (201–238)	<0.001
Alcohol consumption, n (%)	1855 (14.1)	2808 (18.8)	3189 (24.3)	2384 (28.9)	1148 (32.3)	366 (38.5)	<0.001
Breast cancer, n (%)	7940 (60.3)	7653 (51.1)	5641 (43.1)	2863 (34.7)	1002 (28.2)	170 (17.9)	<0.001
Colorectal cancer, n (%)	2982 (22.7)	4459 (29.8)	4862 (37.1)	3811 (46.2)	1938 (54.5)	575 (60.5)	<0.001
Stomach cancer, n (%)	2485 (18.9)	3174 (21.2)	2899 (22.1)	1736 (21.1)	714 (20.1)	227 (23.9)	<0.001
The number of cancers
1, n (%)	12,914 (98.1)	14,652 (97.9)	12 792(97.7)	8 086(98.0)	3,453 (97.2)	930 (97.8)	0.009
2, n (%)	239 (1.8)	314 (2.1)	305 (2.3)	159 (1.9)	99 (2.8)	21 (2.2)
3, n (%)	5 (0)	2 (0)	0 (0)	2 (0)	1 (0)	0 (0)

Number of non-ideal Life’s Simple 7

0–1 (n = 13 158)

2 (n = 14 968)

3 (n = 13 097)

4 (n = 8 247)

5 (n = 3 553)

6–7 (n = 951)

P-value

The number of non-ideal cardiovascular health components

0, n (%)

2 913 (22.1)

0 (0)

<0.001

1, n (%)

10 245 (77.9)

0 (0)

2, n (%)

0 (0)

14 968 (100)

0 (0)

3, n (%)

0 (0)

13 097 (100)

0 (0)

4, n (%)

0 (0)

8 247 (100)

0 (0)

5, n (%)

0 (0)

3,553 (100)

0 (0)

6, n (%)

0 (0)

851 (89.5)

7, n (%)

0 (0)

100 (10.5)

Non-ideal body mass index, n (%)

145 (1.1)

1013 (6.8)

2767 (21.1)

4001 (48.5)

2677 (75.3)

821 (86.3)

<0.001

Non-ideal smoking, n (%)

235 (1.8)

1064 (7.1)

1753 (13.4)

1976 (24.0)

1273 (35.8)

699 (73.5)

<0.001

Non-ideal physical activity, n (%)

3405 (25.9)

7342 (49.1)

7798 (59.5)

5913 (71.7)

3062 (86.2)

886 (93.2)

<0.001

Non-ideal eating habit, n (%)

264 (2.0)

1,072 (7.2)

1,699 (13.0)

1,644 (19.9)

1,148 (32.3)

670 (70.5)

<0.001

Non-ideal blood pressure, n (%)

2026 (15.4)

7677 (51.3)

10 196 (77.8)

7329 (88.9)

3376 (95.0)

932 (98.0)

<0.001

Non-ideal fasting glucose, n (%)

434 (3.3)

2302 (15.4)

5003 (38.2)

5208 (63.2)

2936 (82.6)

872 (91.7)

<0.001

Non-ideal total cholesterol, n (%)

3,736 (28.4)

9,466 (63.2)

10,075 (76.9)

6,917 (83.9)

3,293 (92.7)

926 (97.4)

<0.001

Age, years

50 (45–56)

54 (48–60)

56 (50–62)

57 (51–62)

56 (51–62)

55 (50–60)

<0.001

Men, n (%)

2836 (21.6)

4722 (31.5)

5523 (42.2)

4377 (53.1)

2202 (62.0)

726 (76.3)

<0.001

Body mass index, kg/m²

20.3 (18.8–21.9)

21.2 (19.4–23)

22.5 (20.4–24.5)

24.8 (22–27)

26.4 (25–28.7)

27.1 (25.5–29.3)

<0.001

Systolic blood pressure, mmHg

108 (100–115)

117 (107–128)

125 (116–135)

128 (120–138)

130 (123–140)

131 (123–140)

<0.001

Diastolic blood pressure, mmHg

67 (61–73)

73 (66–81)

78 (70–84)

80 (73–87)

82 (76–89)

83 (77–89)

<0.001

Glucose, mg/dL

89 (84–94)

91.5 (86–97)

96 (89–104)

102 (94–111)

106 (101–118)

109 (103–123)

<0.001

Total cholesterol, mg/dL

187 (170–204)

208 (186–231)

215 (194–239)

216 (197–238)

218 (201–242)

218.5 (201–238)

<0.001

Alcohol consumption, n (%)

1855 (14.1)

2808 (18.8)

3189 (24.3)

2384 (28.9)

1148 (32.3)

366 (38.5)

<0.001

Breast cancer, n (%)

7940 (60.3)

7653 (51.1)

5641 (43.1)

2863 (34.7)

1002 (28.2)

170 (17.9)

<0.001

Colorectal cancer, n (%)

2982 (22.7)

4459 (29.8)

4862 (37.1)

3811 (46.2)

1938 (54.5)

575 (60.5)

<0.001

Stomach cancer, n (%)

2485 (18.9)

3174 (21.2)

2899 (22.1)

1736 (21.1)

714 (20.1)

227 (23.9)

<0.001

The number of cancers

1, n (%)

12,914 (98.1)

14,652 (97.9)

12 792(97.7)

8 086(98.0)

3,453 (97.2)

930 (97.8)

0.009

2, n (%)

239 (1.8)

314 (2.1)

305 (2.3)

159 (1.9)

99 (2.8)

21 (2.2)

3, n (%)

5 (0)

2 (0)

0 (0)

2 (0)

1 (0)

0 (0)

	Number of non-ideal Life’s Simple 7
The number of non-ideal cardiovascular health components
0, n (%)	2 913 (22.1)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	<0.001
1, n (%)	10 245 (77.9)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
2, n (%)	0 (0)	14 968 (100)	0 (0)	0 (0)	0 (0)	0 (0)
3, n (%)	0 (0)	0 (0)	13 097 (100)	0 (0)	0 (0)	0 (0)
4, n (%)	0 (0)	0 (0)	0 (0)	8 247 (100)	0 (0)	0 (0)
5, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	3,553 (100)	0 (0)
6, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	851 (89.5)
7, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	100 (10.5)
Non-ideal body mass index, n (%)	145 (1.1)	1013 (6.8)	2767 (21.1)	4001 (48.5)	2677 (75.3)	821 (86.3)	<0.001
Non-ideal smoking, n (%)	235 (1.8)	1064 (7.1)	1753 (13.4)	1976 (24.0)	1273 (35.8)	699 (73.5)	<0.001
Non-ideal physical activity, n (%)	3405 (25.9)	7342 (49.1)	7798 (59.5)	5913 (71.7)	3062 (86.2)	886 (93.2)	<0.001
Non-ideal eating habit, n (%)	264 (2.0)	1,072 (7.2)	1,699 (13.0)	1,644 (19.9)	1,148 (32.3)	670 (70.5)	<0.001
Non-ideal blood pressure, n (%)	2026 (15.4)	7677 (51.3)	10 196 (77.8)	7329 (88.9)	3376 (95.0)	932 (98.0)	<0.001
Non-ideal fasting glucose, n (%)	434 (3.3)	2302 (15.4)	5003 (38.2)	5208 (63.2)	2936 (82.6)	872 (91.7)	<0.001
Non-ideal total cholesterol, n (%)	3,736 (28.4)	9,466 (63.2)	10,075 (76.9)	6,917 (83.9)	3,293 (92.7)	926 (97.4)	<0.001
Age, years	50 (45–56)	54 (48–60)	56 (50–62)	57 (51–62)	56 (51–62)	55 (50–60)	<0.001
Men, n (%)	2836 (21.6)	4722 (31.5)	5523 (42.2)	4377 (53.1)	2202 (62.0)	726 (76.3)	<0.001
Body mass index, kg/m²	20.3 (18.8–21.9)	21.2 (19.4–23)	22.5 (20.4–24.5)	24.8 (22–27)	26.4 (25–28.7)	27.1 (25.5–29.3)	<0.001
Systolic blood pressure, mmHg	108 (100–115)	117 (107–128)	125 (116–135)	128 (120–138)	130 (123–140)	131 (123–140)	<0.001
Diastolic blood pressure, mmHg	67 (61–73)	73 (66–81)	78 (70–84)	80 (73–87)	82 (76–89)	83 (77–89)	<0.001
Glucose, mg/dL	89 (84–94)	91.5 (86–97)	96 (89–104)	102 (94–111)	106 (101–118)	109 (103–123)	<0.001
Total cholesterol, mg/dL	187 (170–204)	208 (186–231)	215 (194–239)	216 (197–238)	218 (201–242)	218.5 (201–238)	<0.001
Alcohol consumption, n (%)	1855 (14.1)	2808 (18.8)	3189 (24.3)	2384 (28.9)	1148 (32.3)	366 (38.5)	<0.001
Breast cancer, n (%)	7940 (60.3)	7653 (51.1)	5641 (43.1)	2863 (34.7)	1002 (28.2)	170 (17.9)	<0.001
Colorectal cancer, n (%)	2982 (22.7)	4459 (29.8)	4862 (37.1)	3811 (46.2)	1938 (54.5)	575 (60.5)	<0.001
Stomach cancer, n (%)	2485 (18.9)	3174 (21.2)	2899 (22.1)	1736 (21.1)	714 (20.1)	227 (23.9)	<0.001
The number of cancers
1, n (%)	12,914 (98.1)	14,652 (97.9)	12 792(97.7)	8 086(98.0)	3,453 (97.2)	930 (97.8)	0.009
2, n (%)	239 (1.8)	314 (2.1)	305 (2.3)	159 (1.9)	99 (2.8)	21 (2.2)
3, n (%)	5 (0)	2 (0)	0 (0)	2 (0)	1 (0)	0 (0)

Number of non-ideal Life’s Simple 7

0–1 (n = 13 158)

2 (n = 14 968)

3 (n = 13 097)

4 (n = 8 247)

5 (n = 3 553)

6–7 (n = 951)

P-value

The number of non-ideal cardiovascular health components

0, n (%)

2 913 (22.1)

0 (0)

<0.001

1, n (%)

10 245 (77.9)

0 (0)

2, n (%)

0 (0)

14 968 (100)

0 (0)

3, n (%)

0 (0)

13 097 (100)

0 (0)

4, n (%)

0 (0)

8 247 (100)

0 (0)

5, n (%)

0 (0)

3,553 (100)

0 (0)

6, n (%)

0 (0)

851 (89.5)

7, n (%)

0 (0)

100 (10.5)

Non-ideal body mass index, n (%)

145 (1.1)

1013 (6.8)

2767 (21.1)

4001 (48.5)

2677 (75.3)

821 (86.3)

<0.001

Non-ideal smoking, n (%)

235 (1.8)

1064 (7.1)

1753 (13.4)

1976 (24.0)

1273 (35.8)

699 (73.5)

<0.001

Non-ideal physical activity, n (%)

3405 (25.9)

7342 (49.1)

7798 (59.5)

5913 (71.7)

3062 (86.2)

886 (93.2)

<0.001

Non-ideal eating habit, n (%)

264 (2.0)

1,072 (7.2)

1,699 (13.0)

1,644 (19.9)

1,148 (32.3)

670 (70.5)

<0.001

Non-ideal blood pressure, n (%)

2026 (15.4)

7677 (51.3)

10 196 (77.8)

7329 (88.9)

3376 (95.0)

932 (98.0)

<0.001

Non-ideal fasting glucose, n (%)

434 (3.3)

2302 (15.4)

5003 (38.2)

5208 (63.2)

2936 (82.6)

872 (91.7)

<0.001

Non-ideal total cholesterol, n (%)

3,736 (28.4)

9,466 (63.2)

10,075 (76.9)

6,917 (83.9)

3,293 (92.7)

926 (97.4)

<0.001

Age, years

50 (45–56)

54 (48–60)

56 (50–62)

57 (51–62)

56 (51–62)

55 (50–60)

<0.001

Men, n (%)

2836 (21.6)

4722 (31.5)

5523 (42.2)

4377 (53.1)

2202 (62.0)

726 (76.3)

<0.001

Body mass index, kg/m²

20.3 (18.8–21.9)

21.2 (19.4–23)

22.5 (20.4–24.5)

24.8 (22–27)

26.4 (25–28.7)

27.1 (25.5–29.3)

<0.001

Systolic blood pressure, mmHg

108 (100–115)

117 (107–128)

125 (116–135)

128 (120–138)

130 (123–140)

131 (123–140)

<0.001

Diastolic blood pressure, mmHg

67 (61–73)

73 (66–81)

78 (70–84)

80 (73–87)

82 (76–89)

83 (77–89)

<0.001

Glucose, mg/dL

89 (84–94)

91.5 (86–97)

96 (89–104)

102 (94–111)

106 (101–118)

109 (103–123)

<0.001

Total cholesterol, mg/dL

187 (170–204)

208 (186–231)

215 (194–239)

216 (197–238)

218 (201–242)

218.5 (201–238)

<0.001

Alcohol consumption, n (%)

1855 (14.1)

2808 (18.8)

3189 (24.3)

2384 (28.9)

1148 (32.3)

366 (38.5)

<0.001

Breast cancer, n (%)

7940 (60.3)

7653 (51.1)

5641 (43.1)

2863 (34.7)

1002 (28.2)

170 (17.9)

<0.001

Colorectal cancer, n (%)

2982 (22.7)

4459 (29.8)

4862 (37.1)

3811 (46.2)

1938 (54.5)

575 (60.5)

<0.001

Stomach cancer, n (%)

2485 (18.9)

3174 (21.2)

2899 (22.1)

1736 (21.1)

714 (20.1)

227 (23.9)

<0.001

The number of cancers

1, n (%)

12,914 (98.1)

14,652 (97.9)

12 792(97.7)

8 086(98.0)

3,453 (97.2)

930 (97.8)

0.009

2, n (%)

239 (1.8)

314 (2.1)

305 (2.3)

159 (1.9)

99 (2.8)

21 (2.2)

3, n (%)

5 (0)

2 (0)

0 (0)

2 (0)

1 (0)

0 (0)

Table 1

Open in new tab

Characteristics of study participants

	Number of non-ideal Life’s Simple 7
	0–1 (n = 13 158)	2 (n = 14 968)	3 (n = 13 097)	4 (n = 8 247)	5 (n = 3 553)	6–7 (n = 951)	P-value
The number of non-ideal cardiovascular health components
0, n (%)	2 913 (22.1)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	<0.001
1, n (%)	10 245 (77.9)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
2, n (%)	0 (0)	14 968 (100)	0 (0)	0 (0)	0 (0)	0 (0)
3, n (%)	0 (0)	0 (0)	13 097 (100)	0 (0)	0 (0)	0 (0)
4, n (%)	0 (0)	0 (0)	0 (0)	8 247 (100)	0 (0)	0 (0)
5, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	3,553 (100)	0 (0)
6, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	851 (89.5)
7, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	100 (10.5)
Non-ideal body mass index, n (%)	145 (1.1)	1013 (6.8)	2767 (21.1)	4001 (48.5)	2677 (75.3)	821 (86.3)	<0.001
Non-ideal smoking, n (%)	235 (1.8)	1064 (7.1)	1753 (13.4)	1976 (24.0)	1273 (35.8)	699 (73.5)	<0.001
Non-ideal physical activity, n (%)	3405 (25.9)	7342 (49.1)	7798 (59.5)	5913 (71.7)	3062 (86.2)	886 (93.2)	<0.001
Non-ideal eating habit, n (%)	264 (2.0)	1,072 (7.2)	1,699 (13.0)	1,644 (19.9)	1,148 (32.3)	670 (70.5)	<0.001
Non-ideal blood pressure, n (%)	2026 (15.4)	7677 (51.3)	10 196 (77.8)	7329 (88.9)	3376 (95.0)	932 (98.0)	<0.001
Non-ideal fasting glucose, n (%)	434 (3.3)	2302 (15.4)	5003 (38.2)	5208 (63.2)	2936 (82.6)	872 (91.7)	<0.001
Non-ideal total cholesterol, n (%)	3,736 (28.4)	9,466 (63.2)	10,075 (76.9)	6,917 (83.9)	3,293 (92.7)	926 (97.4)	<0.001
Age, years	50 (45–56)	54 (48–60)	56 (50–62)	57 (51–62)	56 (51–62)	55 (50–60)	<0.001
Men, n (%)	2836 (21.6)	4722 (31.5)	5523 (42.2)	4377 (53.1)	2202 (62.0)	726 (76.3)	<0.001
Body mass index, kg/m²	20.3 (18.8–21.9)	21.2 (19.4–23)	22.5 (20.4–24.5)	24.8 (22–27)	26.4 (25–28.7)	27.1 (25.5–29.3)	<0.001
Systolic blood pressure, mmHg	108 (100–115)	117 (107–128)	125 (116–135)	128 (120–138)	130 (123–140)	131 (123–140)	<0.001
Diastolic blood pressure, mmHg	67 (61–73)	73 (66–81)	78 (70–84)	80 (73–87)	82 (76–89)	83 (77–89)	<0.001
Glucose, mg/dL	89 (84–94)	91.5 (86–97)	96 (89–104)	102 (94–111)	106 (101–118)	109 (103–123)	<0.001
Total cholesterol, mg/dL	187 (170–204)	208 (186–231)	215 (194–239)	216 (197–238)	218 (201–242)	218.5 (201–238)	<0.001
Alcohol consumption, n (%)	1855 (14.1)	2808 (18.8)	3189 (24.3)	2384 (28.9)	1148 (32.3)	366 (38.5)	<0.001
Breast cancer, n (%)	7940 (60.3)	7653 (51.1)	5641 (43.1)	2863 (34.7)	1002 (28.2)	170 (17.9)	<0.001
Colorectal cancer, n (%)	2982 (22.7)	4459 (29.8)	4862 (37.1)	3811 (46.2)	1938 (54.5)	575 (60.5)	<0.001
Stomach cancer, n (%)	2485 (18.9)	3174 (21.2)	2899 (22.1)	1736 (21.1)	714 (20.1)	227 (23.9)	<0.001
The number of cancers
1, n (%)	12,914 (98.1)	14,652 (97.9)	12 792(97.7)	8 086(98.0)	3,453 (97.2)	930 (97.8)	0.009
2, n (%)	239 (1.8)	314 (2.1)	305 (2.3)	159 (1.9)	99 (2.8)	21 (2.2)
3, n (%)	5 (0)	2 (0)	0 (0)	2 (0)	1 (0)	0 (0)

	Number of non-ideal Life’s Simple 7
	0–1 (n = 13 158)	2 (n = 14 968)	3 (n = 13 097)	4 (n = 8 247)	5 (n = 3 553)	6–7 (n = 951)	P-value
The number of non-ideal cardiovascular health components
0, n (%)	2 913 (22.1)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	<0.001
1, n (%)	10 245 (77.9)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
2, n (%)	0 (0)	14 968 (100)	0 (0)	0 (0)	0 (0)	0 (0)
3, n (%)	0 (0)	0 (0)	13 097 (100)	0 (0)	0 (0)	0 (0)
4, n (%)	0 (0)	0 (0)	0 (0)	8 247 (100)	0 (0)	0 (0)
5, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	3,553 (100)	0 (0)
6, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	851 (89.5)
7, n (%)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	100 (10.5)
Non-ideal body mass index, n (%)	145 (1.1)	1013 (6.8)	2767 (21.1)	4001 (48.5)	2677 (75.3)	821 (86.3)	<0.001
Non-ideal smoking, n (%)	235 (1.8)	1064 (7.1)	1753 (13.4)	1976 (24.0)	1273 (35.8)	699 (73.5)	<0.001
Non-ideal physical activity, n (%)	3405 (25.9)	7342 (49.1)	7798 (59.5)	5913 (71.7)	3062 (86.2)	886 (93.2)	<0.001
Non-ideal eating habit, n (%)	264 (2.0)	1,072 (7.2)	1,699 (13.0)	1,644 (19.9)	1,148 (32.3)	670 (70.5)	<0.001
Non-ideal blood pressure, n (%)	2026 (15.4)	7677 (51.3)	10 196 (77.8)	7329 (88.9)	3376 (95.0)	932 (98.0)	<0.001
Non-ideal fasting glucose, n (%)	434 (3.3)	2302 (15.4)	5003 (38.2)	5208 (63.2)	2936 (82.6)	872 (91.7)	<0.001
Non-ideal total cholesterol, n (%)	3,736 (28.4)	9,466 (63.2)	10,075 (76.9)	6,917 (83.9)	3,293 (92.7)	926 (97.4)	<0.001
Age, years	50 (45–56)	54 (48–60)	56 (50–62)	57 (51–62)	56 (51–62)	55 (50–60)	<0.001
Men, n (%)	2836 (21.6)	4722 (31.5)	5523 (42.2)	4377 (53.1)	2202 (62.0)	726 (76.3)	<0.001
Body mass index, kg/m²	20.3 (18.8–21.9)	21.2 (19.4–23)	22.5 (20.4–24.5)	24.8 (22–27)	26.4 (25–28.7)	27.1 (25.5–29.3)	<0.001
Systolic blood pressure, mmHg	108 (100–115)	117 (107–128)	125 (116–135)	128 (120–138)	130 (123–140)	131 (123–140)	<0.001
Diastolic blood pressure, mmHg	67 (61–73)	73 (66–81)	78 (70–84)	80 (73–87)	82 (76–89)	83 (77–89)	<0.001
Glucose, mg/dL	89 (84–94)	91.5 (86–97)	96 (89–104)	102 (94–111)	106 (101–118)	109 (103–123)	<0.001
Total cholesterol, mg/dL	187 (170–204)	208 (186–231)	215 (194–239)	216 (197–238)	218 (201–242)	218.5 (201–238)	<0.001
Alcohol consumption, n (%)	1855 (14.1)	2808 (18.8)	3189 (24.3)	2384 (28.9)	1148 (32.3)	366 (38.5)	<0.001
Breast cancer, n (%)	7940 (60.3)	7653 (51.1)	5641 (43.1)	2863 (34.7)	1002 (28.2)	170 (17.9)	<0.001
Colorectal cancer, n (%)	2982 (22.7)	4459 (29.8)	4862 (37.1)	3811 (46.2)	1938 (54.5)	575 (60.5)	<0.001
Stomach cancer, n (%)	2485 (18.9)	3174 (21.2)	2899 (22.1)	1736 (21.1)	714 (20.1)	227 (23.9)	<0.001
The number of cancers
1, n (%)	12,914 (98.1)	14,652 (97.9)	12 792(97.7)	8 086(98.0)	3,453 (97.2)	930 (97.8)	0.009
2, n (%)	239 (1.8)	314 (2.1)	305 (2.3)	159 (1.9)	99 (2.8)	21 (2.2)
3, n (%)	5 (0)	2 (0)	0 (0)	2 (0)	1 (0)	0 (0)

Data are expressed as median (interquartile range) or number (percentage).

P-values were calculated using the analysis of variance for continuous variables and χ² tests for categorical variables. Participants were categorized into six groups according to the number of non-ideal cardiovascular health metrics components.

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