Table 1: Open in new tab Patient profile...

	Total, n = 86	RA alone, n = 51	Plus PMR-A, n = 24	Plus PMR-P, n = 11	P-Value
Baseline characteristics
Age (years)	68.0 ± 8.0	69.0 ± 7.2	67.9 ± 8.0	63.2 ± 10.3	0.087
Sex: male	69 (80)	44 (86)	15 (63)	10 (91)	0.035
Height (cm)	162 ± 9	161 ± 7	162 ± 11	164 ± 7	0.655
Weight (kg)	59.3 ± 11.9	60.1 ± 12.2	56.3 ± 12.0	62.1 ± 9.3	0.306
Hypertension	34 (40)	24 (47)	7 (29)	3 (27)	0.225
Diabetes	39 (45)	29 (57)	6 (25)	4 (36)	0.029
eGFR (ml/min/1.73 m²)	47.6 ± 21.3	50.8 ± 19.9	43.9 ± 22.3	41.4 ± 25.0	0.254
Haemodialysis	7 (8)	3 (6)	3 (13)	1 (9)	0.615
BNP (pg/ml)	830 ± 1042	694 ± 833	1088 ± 1443	897 ± 851	0.307
Ischaemic aetiology	64 (74)	49 (96)	7 (29)	8 (73)	<0.001
Atrial fibrillation	26 (30)	13 (26)	9 (38)	4 (36)	0.512
NYHA III or IV	61 (71)	32 (63)	20 (83)	9 (82)	0.130
Echocardiography
LVDd (mm)	65.8 ± 8.2	64.5 ± 8.1	66.6 ± 7.4	70.3 ± 9.5	0.091
LVDs (mm)	53.5 ± 11.0	50.4 ± 11.1	57.2 ± 8.3	60.0 ± 11.1	0.004
LVEDV (ml)	220 ± 71	205 ± 71	231 ± 58	263 ± 81	0.030
LVEF ()	35.9 ± 10.7	38.9 ± 11.8	31.6 ± 7.5	31.6 ± 7.2	0.008
MR mild	4 (5)	4 (8)	0 (0)	0 (0)	0.001
MR moderate	24 (28)	22 (43)	1 (4)	1 (9)
MR severe	58 (67)	25 (49)	23 (96)	10 (91)
Tenting height (mm)	9.1 ± 2.9	7.9 ± 2.7	10.4 ± 2.0	11.5 ± 2.1	<0.001
Tenting area (cm²)	1.61 ± 0.65	1.41 ± 0.63	1.89 ± 0.58	1.85 ± 0.59	0.008
ALOA (°)	57.6 ± 13.2	59.9 ± 13.0	55.7 ± 12.7	52.9 ± 14.4	0.206
ALCA (°)	26.1 ± 10.1	24.3 ± 10.5	29.9 ± 9.8	25.7 ± 7.4	0.104
PLOA (°)	77.2 ± 18.9	78.3 ± 21.3	75.5 ± 14.3	76.7 ± 18.3	0.852
PLCA (°)	51.5 ± 14.6	48.2 ± 15.2	53.9 ± 13.4	59.9 ± 11.0	0.037
Surgical procedures
Ring size (mm)	27.3 ± 1.9	26.9 ± 2.5	28.6 ± 2.5	26.3 ± 1.5	<0.001
CABG	58 (67)	43 (84)	7 (29)	8 (73)	<0.001
Maze	15 (17)	5 (10)	7 (29)	3 (27)	0.078
Tricuspid valve surgery	26 (30)	11 (22)	12 (50)	3 (27)	0.043

Total, n = 86

RA alone, n = 51

Plus PMR-A, n = 24

Plus PMR-P, n = 11

P-Value

Baseline characteristics

Age (years)

68.0 ± 8.0

69.0 ± 7.2

67.9 ± 8.0

63.2 ± 10.3

0.087

Sex: male

69 (80)

44 (86)

15 (63)

10 (91)

0.035

Height (cm)

162 ± 9

161 ± 7

162 ± 11

164 ± 7

0.655

Weight (kg)

59.3 ± 11.9

60.1 ± 12.2

56.3 ± 12.0

62.1 ± 9.3

0.306

Hypertension

34 (40)

24 (47)

7 (29)

3 (27)

0.225

Diabetes

39 (45)

29 (57)

6 (25)

4 (36)

0.029

eGFR (ml/min/1.73 m²)

47.6 ± 21.3

50.8 ± 19.9

43.9 ± 22.3

41.4 ± 25.0

0.254

Haemodialysis

7 (8)

3 (6)

3 (13)

1 (9)

0.615

BNP (pg/ml)

830 ± 1042

694 ± 833

1088 ± 1443

897 ± 851

0.307

Ischaemic aetiology

64 (74)

49 (96)

7 (29)

8 (73)

<0.001

Atrial fibrillation

26 (30)

13 (26)

9 (38)

4 (36)

0.512

NYHA III or IV

61 (71)

32 (63)

20 (83)

9 (82)

0.130

Echocardiography

LVDd (mm)

65.8 ± 8.2

64.5 ± 8.1

66.6 ± 7.4

70.3 ± 9.5

0.091

LVDs (mm)

53.5 ± 11.0

50.4 ± 11.1

57.2 ± 8.3

60.0 ± 11.1

0.004

LVEDV (ml)

220 ± 71

205 ± 71

231 ± 58

263 ± 81

0.030

LVEF ()

35.9 ± 10.7

38.9 ± 11.8

31.6 ± 7.5

31.6 ± 7.2

0.008

MR mild

4 (5)

4 (8)

0 (0)

0.001

MR moderate

24 (28)

22 (43)

1 (4)

1 (9)

MR severe

58 (67)

25 (49)

23 (96)

10 (91)

Tenting height (mm)

9.1 ± 2.9

7.9 ± 2.7

10.4 ± 2.0

11.5 ± 2.1

<0.001

Tenting area (cm²)

1.61 ± 0.65

1.41 ± 0.63

1.89 ± 0.58

1.85 ± 0.59

0.008

ALOA (°)

57.6 ± 13.2

59.9 ± 13.0

55.7 ± 12.7

52.9 ± 14.4

0.206

ALCA (°)

26.1 ± 10.1

24.3 ± 10.5

29.9 ± 9.8

25.7 ± 7.4

0.104

PLOA (°)

77.2 ± 18.9

78.3 ± 21.3

75.5 ± 14.3

76.7 ± 18.3

0.852

PLCA (°)

51.5 ± 14.6

48.2 ± 15.2

53.9 ± 13.4

59.9 ± 11.0

0.037

Surgical procedures

Ring size (mm)

27.3 ± 1.9

26.9 ± 2.5

28.6 ± 2.5

26.3 ± 1.5

<0.001

CABG

58 (67)

43 (84)

7 (29)

8 (73)

<0.001

Maze

15 (17)

5 (10)

7 (29)

3 (27)

0.078

Tricuspid valve surgery

26 (30)

11 (22)

12 (50)

3 (27)

0.043

	Total, n = 86	RA alone, n = 51	Plus PMR-A, n = 24	Plus PMR-P, n = 11	P-Value
Baseline characteristics
Age (years)	68.0 ± 8.0	69.0 ± 7.2	67.9 ± 8.0	63.2 ± 10.3	0.087
Sex: male	69 (80)	44 (86)	15 (63)	10 (91)	0.035
Height (cm)	162 ± 9	161 ± 7	162 ± 11	164 ± 7	0.655
Weight (kg)	59.3 ± 11.9	60.1 ± 12.2	56.3 ± 12.0	62.1 ± 9.3	0.306
Hypertension	34 (40)	24 (47)	7 (29)	3 (27)	0.225
Diabetes	39 (45)	29 (57)	6 (25)	4 (36)	0.029
eGFR (ml/min/1.73 m²)	47.6 ± 21.3	50.8 ± 19.9	43.9 ± 22.3	41.4 ± 25.0	0.254
Haemodialysis	7 (8)	3 (6)	3 (13)	1 (9)	0.615
BNP (pg/ml)	830 ± 1042	694 ± 833	1088 ± 1443	897 ± 851	0.307
Ischaemic aetiology	64 (74)	49 (96)	7 (29)	8 (73)	<0.001
Atrial fibrillation	26 (30)	13 (26)	9 (38)	4 (36)	0.512
NYHA III or IV	61 (71)	32 (63)	20 (83)	9 (82)	0.130
Echocardiography
LVDd (mm)	65.8 ± 8.2	64.5 ± 8.1	66.6 ± 7.4	70.3 ± 9.5	0.091
LVDs (mm)	53.5 ± 11.0	50.4 ± 11.1	57.2 ± 8.3	60.0 ± 11.1	0.004
LVEDV (ml)	220 ± 71	205 ± 71	231 ± 58	263 ± 81	0.030
LVEF ()	35.9 ± 10.7	38.9 ± 11.8	31.6 ± 7.5	31.6 ± 7.2	0.008
MR mild	4 (5)	4 (8)	0 (0)	0 (0)	0.001
MR moderate	24 (28)	22 (43)	1 (4)	1 (9)
MR severe	58 (67)	25 (49)	23 (96)	10 (91)
Tenting height (mm)	9.1 ± 2.9	7.9 ± 2.7	10.4 ± 2.0	11.5 ± 2.1	<0.001
Tenting area (cm²)	1.61 ± 0.65	1.41 ± 0.63	1.89 ± 0.58	1.85 ± 0.59	0.008
ALOA (°)	57.6 ± 13.2	59.9 ± 13.0	55.7 ± 12.7	52.9 ± 14.4	0.206
ALCA (°)	26.1 ± 10.1	24.3 ± 10.5	29.9 ± 9.8	25.7 ± 7.4	0.104
PLOA (°)	77.2 ± 18.9	78.3 ± 21.3	75.5 ± 14.3	76.7 ± 18.3	0.852
PLCA (°)	51.5 ± 14.6	48.2 ± 15.2	53.9 ± 13.4	59.9 ± 11.0	0.037
Surgical procedures
Ring size (mm)	27.3 ± 1.9	26.9 ± 2.5	28.6 ± 2.5	26.3 ± 1.5	<0.001
CABG	58 (67)	43 (84)	7 (29)	8 (73)	<0.001
Maze	15 (17)	5 (10)	7 (29)	3 (27)	0.078
Tricuspid valve surgery	26 (30)	11 (22)	12 (50)	3 (27)	0.043

Table 1:

Open in new tab

Patient profile

	Total, n = 86	RA alone, n = 51	Plus PMR-A, n = 24	Plus PMR-P, n = 11	P-Value
Baseline characteristics
Age (years)	68.0 ± 8.0	69.0 ± 7.2	67.9 ± 8.0	63.2 ± 10.3	0.087
Sex: male	69 (80)	44 (86)	15 (63)	10 (91)	0.035
Height (cm)	162 ± 9	161 ± 7	162 ± 11	164 ± 7	0.655
Weight (kg)	59.3 ± 11.9	60.1 ± 12.2	56.3 ± 12.0	62.1 ± 9.3	0.306
Hypertension	34 (40)	24 (47)	7 (29)	3 (27)	0.225
Diabetes	39 (45)	29 (57)	6 (25)	4 (36)	0.029
eGFR (ml/min/1.73 m²)	47.6 ± 21.3	50.8 ± 19.9	43.9 ± 22.3	41.4 ± 25.0	0.254
Haemodialysis	7 (8)	3 (6)	3 (13)	1 (9)	0.615
BNP (pg/ml)	830 ± 1042	694 ± 833	1088 ± 1443	897 ± 851	0.307
Ischaemic aetiology	64 (74)	49 (96)	7 (29)	8 (73)	<0.001
Atrial fibrillation	26 (30)	13 (26)	9 (38)	4 (36)	0.512
NYHA III or IV	61 (71)	32 (63)	20 (83)	9 (82)	0.130
Echocardiography
LVDd (mm)	65.8 ± 8.2	64.5 ± 8.1	66.6 ± 7.4	70.3 ± 9.5	0.091
LVDs (mm)	53.5 ± 11.0	50.4 ± 11.1	57.2 ± 8.3	60.0 ± 11.1	0.004
LVEDV (ml)	220 ± 71	205 ± 71	231 ± 58	263 ± 81	0.030
LVEF ()	35.9 ± 10.7	38.9 ± 11.8	31.6 ± 7.5	31.6 ± 7.2	0.008
MR mild	4 (5)	4 (8)	0 (0)	0 (0)	0.001
MR moderate	24 (28)	22 (43)	1 (4)	1 (9)
MR severe	58 (67)	25 (49)	23 (96)	10 (91)
Tenting height (mm)	9.1 ± 2.9	7.9 ± 2.7	10.4 ± 2.0	11.5 ± 2.1	<0.001
Tenting area (cm²)	1.61 ± 0.65	1.41 ± 0.63	1.89 ± 0.58	1.85 ± 0.59	0.008
ALOA (°)	57.6 ± 13.2	59.9 ± 13.0	55.7 ± 12.7	52.9 ± 14.4	0.206
ALCA (°)	26.1 ± 10.1	24.3 ± 10.5	29.9 ± 9.8	25.7 ± 7.4	0.104
PLOA (°)	77.2 ± 18.9	78.3 ± 21.3	75.5 ± 14.3	76.7 ± 18.3	0.852
PLCA (°)	51.5 ± 14.6	48.2 ± 15.2	53.9 ± 13.4	59.9 ± 11.0	0.037
Surgical procedures
Ring size (mm)	27.3 ± 1.9	26.9 ± 2.5	28.6 ± 2.5	26.3 ± 1.5	<0.001
CABG	58 (67)	43 (84)	7 (29)	8 (73)	<0.001
Maze	15 (17)	5 (10)	7 (29)	3 (27)	0.078
Tricuspid valve surgery	26 (30)	11 (22)	12 (50)	3 (27)	0.043

	Total, n = 86	RA alone, n = 51	Plus PMR-A, n = 24	Plus PMR-P, n = 11	P-Value
Baseline characteristics
Age (years)	68.0 ± 8.0	69.0 ± 7.2	67.9 ± 8.0	63.2 ± 10.3	0.087
Sex: male	69 (80)	44 (86)	15 (63)	10 (91)	0.035
Height (cm)	162 ± 9	161 ± 7	162 ± 11	164 ± 7	0.655
Weight (kg)	59.3 ± 11.9	60.1 ± 12.2	56.3 ± 12.0	62.1 ± 9.3	0.306
Hypertension	34 (40)	24 (47)	7 (29)	3 (27)	0.225
Diabetes	39 (45)	29 (57)	6 (25)	4 (36)	0.029
eGFR (ml/min/1.73 m²)	47.6 ± 21.3	50.8 ± 19.9	43.9 ± 22.3	41.4 ± 25.0	0.254
Haemodialysis	7 (8)	3 (6)	3 (13)	1 (9)	0.615
BNP (pg/ml)	830 ± 1042	694 ± 833	1088 ± 1443	897 ± 851	0.307
Ischaemic aetiology	64 (74)	49 (96)	7 (29)	8 (73)	<0.001
Atrial fibrillation	26 (30)	13 (26)	9 (38)	4 (36)	0.512
NYHA III or IV	61 (71)	32 (63)	20 (83)	9 (82)	0.130
Echocardiography
LVDd (mm)	65.8 ± 8.2	64.5 ± 8.1	66.6 ± 7.4	70.3 ± 9.5	0.091
LVDs (mm)	53.5 ± 11.0	50.4 ± 11.1	57.2 ± 8.3	60.0 ± 11.1	0.004
LVEDV (ml)	220 ± 71	205 ± 71	231 ± 58	263 ± 81	0.030
LVEF ()	35.9 ± 10.7	38.9 ± 11.8	31.6 ± 7.5	31.6 ± 7.2	0.008
MR mild	4 (5)	4 (8)	0 (0)	0 (0)	0.001
MR moderate	24 (28)	22 (43)	1 (4)	1 (9)
MR severe	58 (67)	25 (49)	23 (96)	10 (91)
Tenting height (mm)	9.1 ± 2.9	7.9 ± 2.7	10.4 ± 2.0	11.5 ± 2.1	<0.001
Tenting area (cm²)	1.61 ± 0.65	1.41 ± 0.63	1.89 ± 0.58	1.85 ± 0.59	0.008
ALOA (°)	57.6 ± 13.2	59.9 ± 13.0	55.7 ± 12.7	52.9 ± 14.4	0.206
ALCA (°)	26.1 ± 10.1	24.3 ± 10.5	29.9 ± 9.8	25.7 ± 7.4	0.104
PLOA (°)	77.2 ± 18.9	78.3 ± 21.3	75.5 ± 14.3	76.7 ± 18.3	0.852
PLCA (°)	51.5 ± 14.6	48.2 ± 15.2	53.9 ± 13.4	59.9 ± 11.0	0.037
Surgical procedures
Ring size (mm)	27.3 ± 1.9	26.9 ± 2.5	28.6 ± 2.5	26.3 ± 1.5	<0.001
CABG	58 (67)	43 (84)	7 (29)	8 (73)	<0.001
Maze	15 (17)	5 (10)	7 (29)	3 (27)	0.078
Tricuspid valve surgery	26 (30)	11 (22)	12 (50)	3 (27)	0.043

Values are presented as mean ± SD or actual values (%).

ALCA: anterior leaflet closing angle; ALOA: anterior leaflet opening angle; BNP: B-type natriuretic peptide; CABG: coronary artery bypass grafting; eGFR: estimated glomerular filtration rate; LVDd: left ventricular end-diastolic diameter; LVDs: left ventricular end-systolic diameter; LVEDV: left ventricular end-diastolic volume; LVEF: left ventricular ejection fraction; MR: mitral regurgitation; NYHA: New York Heart Association functional classification; PLCA: posterior leaflet closing angle; PLOA: posterior leaflet opening angle; PMR-A: papillary muscle relocation anteriorly; PMR-P: papillary muscle relocation posteriorly; RA: restrictive annuloplasty; SD: standard deviation.

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