Table 3. Open in new tab Relevant...

Therapy

References

Neck wrinkle condition of the patients

Functional effects

BTX-A

^6-8

Mild to moderate

Reduce platysmal bands and marginally improve neck lines

Skin tissue filler

Hyaluronic acid

^26-29

Mild to moderate

Restore soft tissue volume

Polylactic acid

³⁰

Not mentioned

Stimulate fibroblasts to proliferate and secrete collagen

Calcium hydroxyapatite

³¹

Class I-III (Dedo’s classification system)

Dual-function filler intended to volumize immediately and then stimulate neocollagenesis through local fibrohistiocytic response

Stromal vascular fraction gel

³²

Mild to deep

Increase the collagen density of neck wrinkles

Intradermal radiofrequency

³³

Not mentioned

Nonablative skin rejuvenation through its thermal effects

Thread lift implantation

³⁴

Shallow to moderately deep

Stimulate fibroblast, collagenization, and neoangiogenesis to improve skin texture and laxity

Microfocused ultrasound

^35,36

Moderate to severe

Tighten and lift lax neck skin

Laser treatment

^37,38

Mild to moderate

Improve skin texture and neck laxity, nonablative skin remodeling of neck lines

Platelet-rich plasma

³⁹

Not mentioned

Improve micropigmentation, skin texture, and skin homogeneity

Mesoderm therapy

⁴⁰

Not mentioned

Promote collagen regeneration and improve tightness and smoothness of neck skin

Autologous keratin and fibroblast

⁴¹

Mild to severe

Support tissue scaffolds and continuous secretion collagen

Table 3.

Open in new tab

Relevant Minimally Invasive Treatments for Neck Wrinkles

Therapy		References	Neck wrinkle condition of the patients	Functional effects
BTX-A		^6-8	Mild to moderate	Reduce platysmal bands and marginally improve neck lines
Skin tissue filler	Hyaluronic acid	^26-29	Mild to moderate	Restore soft tissue volume
	Polylactic acid	³⁰	Not mentioned	Stimulate fibroblasts to proliferate and secrete collagen
	Calcium hydroxyapatite	³¹	Class I-III (Dedo’s classification system)	Dual-function filler intended to volumize immediately and then stimulate neocollagenesis through local fibrohistiocytic response
Stromal vascular fraction gel		³²	Mild to deep	Increase the collagen density of neck wrinkles
Intradermal radiofrequency		³³	Not mentioned	Nonablative skin rejuvenation through its thermal effects
Thread lift implantation		³⁴	Shallow to moderately deep	Stimulate fibroblast, collagenization, and neoangiogenesis to improve skin texture and laxity
Microfocused ultrasound		^35,36	Moderate to severe	Tighten and lift lax neck skin
Laser treatment		^37,38	Mild to moderate	Improve skin texture and neck laxity, nonablative skin remodeling of neck lines
Platelet-rich plasma		³⁹	Not mentioned	Improve micropigmentation, skin texture, and skin homogeneity
Mesoderm therapy		⁴⁰	Not mentioned	Promote collagen regeneration and improve tightness and smoothness of neck skin
Autologous keratin and fibroblast		⁴¹	Mild to severe	Support tissue scaffolds and continuous secretion collagen

Therapy		References	Neck wrinkle condition of the patients	Functional effects
BTX-A		^6-8	Mild to moderate	Reduce platysmal bands and marginally improve neck lines
Skin tissue filler	Hyaluronic acid	^26-29	Mild to moderate	Restore soft tissue volume
	Polylactic acid	³⁰	Not mentioned	Stimulate fibroblasts to proliferate and secrete collagen
	Calcium hydroxyapatite	³¹	Class I-III (Dedo’s classification system)	Dual-function filler intended to volumize immediately and then stimulate neocollagenesis through local fibrohistiocytic response
Stromal vascular fraction gel		³²	Mild to deep	Increase the collagen density of neck wrinkles
Intradermal radiofrequency		³³	Not mentioned	Nonablative skin rejuvenation through its thermal effects
Thread lift implantation		³⁴	Shallow to moderately deep	Stimulate fibroblast, collagenization, and neoangiogenesis to improve skin texture and laxity
Microfocused ultrasound		^35,36	Moderate to severe	Tighten and lift lax neck skin
Laser treatment		^37,38	Mild to moderate	Improve skin texture and neck laxity, nonablative skin remodeling of neck lines
Platelet-rich plasma		³⁹	Not mentioned	Improve micropigmentation, skin texture, and skin homogeneity
Mesoderm therapy		⁴⁰	Not mentioned	Promote collagen regeneration and improve tightness and smoothness of neck skin
Autologous keratin and fibroblast		⁴¹	Mild to severe	Support tissue scaffolds and continuous secretion collagen

BTX-A = botulinum toxin A.

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