Performance comparison of different network construction methods based on different modal data
| Data . | Method . | NC versus AD . | EMCI versus LMCI . | LMCI versus AD . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ||
| fMRI | SCC | 78.72 | 76.09 | 81.25 | 78.67 | 75.00 | 72.92 | 78.13 | 75.52 | 77.08 | 73.47 | 80.85 | 77.16 |
| KCC | 79.79 | 77.78 | 81.63 | 79.71 | 76.25 | 75.00 | 78.12 | 76.56 | 78.13 | 74.47 | 81.63 | 78.05 | |
| PCC | 87.23 | 77.27 | 90.28 | 83.38 | 85.00 | 85.71 | 84.21 | 84.96 | 84.38 | 85.37 | 83.64 | 84.50 | |
| SNP | SCC | 75.53 | 76.6 | 74.47 | 75.53 | 72.50 | 71.15 | 75.00 | 73.08 | 73.96 | 70.00 | 78.26 | 74.13 |
| KCC | 77.66 | 74.47 | 80.85 | 77.66 | 73.75 | 71.42 | 77.42 | 74.42 | 76.04 | 73.47 | 78.72 | 76.10 | |
| PCC | 84.48 | 87.50 | 81.48 | 84.49 | 83.75 | 88.37 | 78.38 | 83.38 | 83.33 | 81.40 | 84.91 | 83.15 | |
| Dual | SCC | 82.98 | 83.33 | 82.69 | 83.01 | 78.75 | 76.09 | 82.35 | 79.22 | 79.17 | 78.26 | 80.00 | 79.13 |
| KCC | 84.04 | 85.37 | 83.02 | 84.19 | 80.00 | 78.26 | 82.35 | 80.21 | 80.21 | 79.55 | 80.77 | 80.16 | |
| PCC | 93.62 | 95.35 | 92.16 | 93.75 | 91.25 | 91.67 | 90.63 | 91.15 | 91.95 | 92.11 | 91.84 | 91.97 | |
| Data . | Method . | NC versus AD . | EMCI versus LMCI . | LMCI versus AD . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ||
| fMRI | SCC | 78.72 | 76.09 | 81.25 | 78.67 | 75.00 | 72.92 | 78.13 | 75.52 | 77.08 | 73.47 | 80.85 | 77.16 |
| KCC | 79.79 | 77.78 | 81.63 | 79.71 | 76.25 | 75.00 | 78.12 | 76.56 | 78.13 | 74.47 | 81.63 | 78.05 | |
| PCC | 87.23 | 77.27 | 90.28 | 83.38 | 85.00 | 85.71 | 84.21 | 84.96 | 84.38 | 85.37 | 83.64 | 84.50 | |
| SNP | SCC | 75.53 | 76.6 | 74.47 | 75.53 | 72.50 | 71.15 | 75.00 | 73.08 | 73.96 | 70.00 | 78.26 | 74.13 |
| KCC | 77.66 | 74.47 | 80.85 | 77.66 | 73.75 | 71.42 | 77.42 | 74.42 | 76.04 | 73.47 | 78.72 | 76.10 | |
| PCC | 84.48 | 87.50 | 81.48 | 84.49 | 83.75 | 88.37 | 78.38 | 83.38 | 83.33 | 81.40 | 84.91 | 83.15 | |
| Dual | SCC | 82.98 | 83.33 | 82.69 | 83.01 | 78.75 | 76.09 | 82.35 | 79.22 | 79.17 | 78.26 | 80.00 | 79.13 |
| KCC | 84.04 | 85.37 | 83.02 | 84.19 | 80.00 | 78.26 | 82.35 | 80.21 | 80.21 | 79.55 | 80.77 | 80.16 | |
| PCC | 93.62 | 95.35 | 92.16 | 93.75 | 91.25 | 91.67 | 90.63 | 91.15 | 91.95 | 92.11 | 91.84 | 91.97 | |
The bold values indicate the highest results of each indicator under each classification task and each data modality, and the proposed approach always performs the best.
Performance comparison of different network construction methods based on different modal data
| Data . | Method . | NC versus AD . | EMCI versus LMCI . | LMCI versus AD . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ||
| fMRI | SCC | 78.72 | 76.09 | 81.25 | 78.67 | 75.00 | 72.92 | 78.13 | 75.52 | 77.08 | 73.47 | 80.85 | 77.16 |
| KCC | 79.79 | 77.78 | 81.63 | 79.71 | 76.25 | 75.00 | 78.12 | 76.56 | 78.13 | 74.47 | 81.63 | 78.05 | |
| PCC | 87.23 | 77.27 | 90.28 | 83.38 | 85.00 | 85.71 | 84.21 | 84.96 | 84.38 | 85.37 | 83.64 | 84.50 | |
| SNP | SCC | 75.53 | 76.6 | 74.47 | 75.53 | 72.50 | 71.15 | 75.00 | 73.08 | 73.96 | 70.00 | 78.26 | 74.13 |
| KCC | 77.66 | 74.47 | 80.85 | 77.66 | 73.75 | 71.42 | 77.42 | 74.42 | 76.04 | 73.47 | 78.72 | 76.10 | |
| PCC | 84.48 | 87.50 | 81.48 | 84.49 | 83.75 | 88.37 | 78.38 | 83.38 | 83.33 | 81.40 | 84.91 | 83.15 | |
| Dual | SCC | 82.98 | 83.33 | 82.69 | 83.01 | 78.75 | 76.09 | 82.35 | 79.22 | 79.17 | 78.26 | 80.00 | 79.13 |
| KCC | 84.04 | 85.37 | 83.02 | 84.19 | 80.00 | 78.26 | 82.35 | 80.21 | 80.21 | 79.55 | 80.77 | 80.16 | |
| PCC | 93.62 | 95.35 | 92.16 | 93.75 | 91.25 | 91.67 | 90.63 | 91.15 | 91.95 | 92.11 | 91.84 | 91.97 | |
| Data . | Method . | NC versus AD . | EMCI versus LMCI . | LMCI versus AD . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ACC (%) . | SEN (%) . | SPE (%) . | BAC (%) . | ||
| fMRI | SCC | 78.72 | 76.09 | 81.25 | 78.67 | 75.00 | 72.92 | 78.13 | 75.52 | 77.08 | 73.47 | 80.85 | 77.16 |
| KCC | 79.79 | 77.78 | 81.63 | 79.71 | 76.25 | 75.00 | 78.12 | 76.56 | 78.13 | 74.47 | 81.63 | 78.05 | |
| PCC | 87.23 | 77.27 | 90.28 | 83.38 | 85.00 | 85.71 | 84.21 | 84.96 | 84.38 | 85.37 | 83.64 | 84.50 | |
| SNP | SCC | 75.53 | 76.6 | 74.47 | 75.53 | 72.50 | 71.15 | 75.00 | 73.08 | 73.96 | 70.00 | 78.26 | 74.13 |
| KCC | 77.66 | 74.47 | 80.85 | 77.66 | 73.75 | 71.42 | 77.42 | 74.42 | 76.04 | 73.47 | 78.72 | 76.10 | |
| PCC | 84.48 | 87.50 | 81.48 | 84.49 | 83.75 | 88.37 | 78.38 | 83.38 | 83.33 | 81.40 | 84.91 | 83.15 | |
| Dual | SCC | 82.98 | 83.33 | 82.69 | 83.01 | 78.75 | 76.09 | 82.35 | 79.22 | 79.17 | 78.26 | 80.00 | 79.13 |
| KCC | 84.04 | 85.37 | 83.02 | 84.19 | 80.00 | 78.26 | 82.35 | 80.21 | 80.21 | 79.55 | 80.77 | 80.16 | |
| PCC | 93.62 | 95.35 | 92.16 | 93.75 | 91.25 | 91.67 | 90.63 | 91.15 | 91.95 | 92.11 | 91.84 | 91.97 | |
The bold values indicate the highest results of each indicator under each classification task and each data modality, and the proposed approach always performs the best.
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