Frequency of plaques containing lipid and calcium components and its overlap in ACS-causing culprit lesions with ruptured and intact fibrous cap
| Parameter . | RFC-ACS (n = 204) . | IFC-ACS (n = 78) . | P-value . |
|---|---|---|---|
| Lipid components (LC) present, n (%) | 204 (100) | 63 (80.8) | <0.001 |
| Calcium components (CC) present, n (%) | 164 (80.4) | 43 (55.1) | <0.001 |
| Coexisting components (LCC) present, n (%) | 157 (77.0) | 29 (37.2) | <0.001 |
| Minimum lumen area (MLA) (mm2; mean ± SD) | 1.9 (0.6) | 2.3 (1.7) | ns |
| Thin cap fibroatheroma, n (%) | 198 (97.1) | 19 (24.4) | <0.001 |
| Mean FC thickness (µm; mean ± SD) | 56.2 (15.2) | 107.6 (60.5) | <0.001 |
| Macrophages present, n (%) | 202 (99.0) | 64 (82.1) | <0.001 |
| Parameter . | RFC-ACS (n = 204) . | IFC-ACS (n = 78) . | P-value . |
|---|---|---|---|
| Lipid components (LC) present, n (%) | 204 (100) | 63 (80.8) | <0.001 |
| Calcium components (CC) present, n (%) | 164 (80.4) | 43 (55.1) | <0.001 |
| Coexisting components (LCC) present, n (%) | 157 (77.0) | 29 (37.2) | <0.001 |
| Minimum lumen area (MLA) (mm2; mean ± SD) | 1.9 (0.6) | 2.3 (1.7) | ns |
| Thin cap fibroatheroma, n (%) | 198 (97.1) | 19 (24.4) | <0.001 |
| Mean FC thickness (µm; mean ± SD) | 56.2 (15.2) | 107.6 (60.5) | <0.001 |
| Macrophages present, n (%) | 202 (99.0) | 64 (82.1) | <0.001 |
The presence of each individual component along the entire culprit lesion; mean FC thickness refers to fibrous caps, overlying a fibroatheroma.
IFC-ACS, intact-fibrous cap acute coronary syndrome; LCC, lipid- and calcified plaque components; n, number; RFC-ACS, ruptured-fibrous cap acute coronary syndrome.
Frequency of plaques containing lipid and calcium components and its overlap in ACS-causing culprit lesions with ruptured and intact fibrous cap
| Parameter . | RFC-ACS (n = 204) . | IFC-ACS (n = 78) . | P-value . |
|---|---|---|---|
| Lipid components (LC) present, n (%) | 204 (100) | 63 (80.8) | <0.001 |
| Calcium components (CC) present, n (%) | 164 (80.4) | 43 (55.1) | <0.001 |
| Coexisting components (LCC) present, n (%) | 157 (77.0) | 29 (37.2) | <0.001 |
| Minimum lumen area (MLA) (mm2; mean ± SD) | 1.9 (0.6) | 2.3 (1.7) | ns |
| Thin cap fibroatheroma, n (%) | 198 (97.1) | 19 (24.4) | <0.001 |
| Mean FC thickness (µm; mean ± SD) | 56.2 (15.2) | 107.6 (60.5) | <0.001 |
| Macrophages present, n (%) | 202 (99.0) | 64 (82.1) | <0.001 |
| Parameter . | RFC-ACS (n = 204) . | IFC-ACS (n = 78) . | P-value . |
|---|---|---|---|
| Lipid components (LC) present, n (%) | 204 (100) | 63 (80.8) | <0.001 |
| Calcium components (CC) present, n (%) | 164 (80.4) | 43 (55.1) | <0.001 |
| Coexisting components (LCC) present, n (%) | 157 (77.0) | 29 (37.2) | <0.001 |
| Minimum lumen area (MLA) (mm2; mean ± SD) | 1.9 (0.6) | 2.3 (1.7) | ns |
| Thin cap fibroatheroma, n (%) | 198 (97.1) | 19 (24.4) | <0.001 |
| Mean FC thickness (µm; mean ± SD) | 56.2 (15.2) | 107.6 (60.5) | <0.001 |
| Macrophages present, n (%) | 202 (99.0) | 64 (82.1) | <0.001 |
The presence of each individual component along the entire culprit lesion; mean FC thickness refers to fibrous caps, overlying a fibroatheroma.
IFC-ACS, intact-fibrous cap acute coronary syndrome; LCC, lipid- and calcified plaque components; n, number; RFC-ACS, ruptured-fibrous cap acute coronary syndrome.
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