Echocardiographic parameters of RV size and systolic function on patients with a systemic RV and healthy volunteers
| Parameter . | Control group (N = 38) . | All SRV patients (N = 38) . | TGA post-atrial switch repair (N = 24) . | ccTGA (N = 14) . |
|---|---|---|---|---|
| Basal diameter, cm | 3.2 ± 0.4 | 5.5 ± 1.1; P < 0.0001 | 5.6 ± 1.0 | 5.3 ± 1.2; P = 0.432 |
| Mid diameter, cm | 2.2 ± 0.3 | 5.1 ± 9.8; P < 0.0001 | 4.8 ± 7.0 | 5.6 ± 1.2; P = 0.017 |
| Length, cm | 7.9 ± 0.6 | 7.9 ± 1.2; P = 0.803 | 8.1 ± 1.1 | 7.6 ± 1.3; P = 0.149 |
| EDAi, cm2/m2 | 14 ± 3.1 | 20 ± 5.1; P < 0.0001 | 21 ± 4.0 | 19 ± 6.4; P = 0.062 |
| ESAi, cm2/m2 | 9 ± 1.9 | 15 ± 5.0; P < 0.0001 | 15 ± 4.9 | 14 ± 5.3; P = 0.498 |
| FAC, % | 41 ± 4 | 27 ± 9; P < 0.0001 | 26 ± 8.8 | 28 ± 9.6; P = 0.486 |
| TAPSE, mm | 25 ± 4.0 | 12 ± 4.2; P < 0.0001 | 11 ± 2.8 | 14 ± 5.4; P = 0.037 |
| S′, cm/s | 15 ± 2.5 | 6.7 ± 2.3; P < 0.0001 | 6.3 ± 2.1 | 7.5 ± 2.7; P = 0.176 |
| RV 4-chamber LS, % | −22 ± 2.6 | −14 ± 3.2; P < 0.0001 | −13 ± 2.9 | −15 ± 3.4; P = 0.114 |
| RV free wall LS, % | −26 ± 3.8 | −15 ± 3.2; P < 0.0001 | −15 ± 2.8 | −16 ± 3.6; P = 0.165 |
| 3D EDVi, mL/m2 | 60 ± 12 | 121 ± 43; P < 0.0001 | 124 ± 30 | 115 ± 61; P = 0.345 |
| 3D ESVi, mL/m2 | 30 ± 7.2 | 80 ± 38; P < 0.0001 | 83 ± 27 | 75 ± 53; P = 0.161 |
| 3D EF, % | 60 ± 4 | 36 ± 8; P < 0.0001 | 34 ± 7 | 38 ± 9; P = 0.179 |
| Components of RV EF | ||||
| LEF, % | 25 ± 4.6 | 12 ± 5.0; P < 0.0001 | 10 ± 3.3 | 15 ± 5.7; P < 0.0001 |
| REF, % | 30 ± 6.4 | 14 ± 5.9; P < 0.0001 | 13 ± 4.9 | 16 ± 7.1; P = 0.075 |
| AEF, % | 29 ± 4.2 | 16 ± 4.7; P < 0.0001 | 17 ± 4.5 | 14 ± 4.7; P = 0.171 |
| LEFi | 0.42 ± 0.08 | 0.33 ± 0.10; P = 0.0002 | 0.29 ± 0.08 | 0.41 ± 0.11; P = 0.0008 |
| REFi | 0.51 ± 0.09 | 0.39 ± 0.11; P < 0.0001 | 0.38 ± 0.10 | 0.41 ± 0.11; P = 0.370 |
| AEFi | 0.48 ± 0.06 | 0.44 ± 0.10; P = 0.026 | 0.48 ± 0.09 | 0.36 ± 0.08; P = 0.0002 |
| Parameter . | Control group (N = 38) . | All SRV patients (N = 38) . | TGA post-atrial switch repair (N = 24) . | ccTGA (N = 14) . |
|---|---|---|---|---|
| Basal diameter, cm | 3.2 ± 0.4 | 5.5 ± 1.1; P < 0.0001 | 5.6 ± 1.0 | 5.3 ± 1.2; P = 0.432 |
| Mid diameter, cm | 2.2 ± 0.3 | 5.1 ± 9.8; P < 0.0001 | 4.8 ± 7.0 | 5.6 ± 1.2; P = 0.017 |
| Length, cm | 7.9 ± 0.6 | 7.9 ± 1.2; P = 0.803 | 8.1 ± 1.1 | 7.6 ± 1.3; P = 0.149 |
| EDAi, cm2/m2 | 14 ± 3.1 | 20 ± 5.1; P < 0.0001 | 21 ± 4.0 | 19 ± 6.4; P = 0.062 |
| ESAi, cm2/m2 | 9 ± 1.9 | 15 ± 5.0; P < 0.0001 | 15 ± 4.9 | 14 ± 5.3; P = 0.498 |
| FAC, % | 41 ± 4 | 27 ± 9; P < 0.0001 | 26 ± 8.8 | 28 ± 9.6; P = 0.486 |
| TAPSE, mm | 25 ± 4.0 | 12 ± 4.2; P < 0.0001 | 11 ± 2.8 | 14 ± 5.4; P = 0.037 |
| S′, cm/s | 15 ± 2.5 | 6.7 ± 2.3; P < 0.0001 | 6.3 ± 2.1 | 7.5 ± 2.7; P = 0.176 |
| RV 4-chamber LS, % | −22 ± 2.6 | −14 ± 3.2; P < 0.0001 | −13 ± 2.9 | −15 ± 3.4; P = 0.114 |
| RV free wall LS, % | −26 ± 3.8 | −15 ± 3.2; P < 0.0001 | −15 ± 2.8 | −16 ± 3.6; P = 0.165 |
| 3D EDVi, mL/m2 | 60 ± 12 | 121 ± 43; P < 0.0001 | 124 ± 30 | 115 ± 61; P = 0.345 |
| 3D ESVi, mL/m2 | 30 ± 7.2 | 80 ± 38; P < 0.0001 | 83 ± 27 | 75 ± 53; P = 0.161 |
| 3D EF, % | 60 ± 4 | 36 ± 8; P < 0.0001 | 34 ± 7 | 38 ± 9; P = 0.179 |
| Components of RV EF | ||||
| LEF, % | 25 ± 4.6 | 12 ± 5.0; P < 0.0001 | 10 ± 3.3 | 15 ± 5.7; P < 0.0001 |
| REF, % | 30 ± 6.4 | 14 ± 5.9; P < 0.0001 | 13 ± 4.9 | 16 ± 7.1; P = 0.075 |
| AEF, % | 29 ± 4.2 | 16 ± 4.7; P < 0.0001 | 17 ± 4.5 | 14 ± 4.7; P = 0.171 |
| LEFi | 0.42 ± 0.08 | 0.33 ± 0.10; P = 0.0002 | 0.29 ± 0.08 | 0.41 ± 0.11; P = 0.0008 |
| REFi | 0.51 ± 0.09 | 0.39 ± 0.11; P < 0.0001 | 0.38 ± 0.10 | 0.41 ± 0.11; P = 0.370 |
| AEFi | 0.48 ± 0.06 | 0.44 ± 0.10; P = 0.026 | 0.48 ± 0.09 | 0.36 ± 0.08; P = 0.0002 |
Data are presented as mean ± SD.
P (in All SRV) value indicates difference compared with the control group.
P (in ccTGA) value indicates difference compared with the TGA group.
EDAi, indexed end-diastolic area; EDVi, indexed end-diastolic volume; ESAi, indexed end-systolic area; ESVi, indexed end-systolic volume; LS, longitudinal strain.
Echocardiographic parameters of RV size and systolic function on patients with a systemic RV and healthy volunteers
| Parameter . | Control group (N = 38) . | All SRV patients (N = 38) . | TGA post-atrial switch repair (N = 24) . | ccTGA (N = 14) . |
|---|---|---|---|---|
| Basal diameter, cm | 3.2 ± 0.4 | 5.5 ± 1.1; P < 0.0001 | 5.6 ± 1.0 | 5.3 ± 1.2; P = 0.432 |
| Mid diameter, cm | 2.2 ± 0.3 | 5.1 ± 9.8; P < 0.0001 | 4.8 ± 7.0 | 5.6 ± 1.2; P = 0.017 |
| Length, cm | 7.9 ± 0.6 | 7.9 ± 1.2; P = 0.803 | 8.1 ± 1.1 | 7.6 ± 1.3; P = 0.149 |
| EDAi, cm2/m2 | 14 ± 3.1 | 20 ± 5.1; P < 0.0001 | 21 ± 4.0 | 19 ± 6.4; P = 0.062 |
| ESAi, cm2/m2 | 9 ± 1.9 | 15 ± 5.0; P < 0.0001 | 15 ± 4.9 | 14 ± 5.3; P = 0.498 |
| FAC, % | 41 ± 4 | 27 ± 9; P < 0.0001 | 26 ± 8.8 | 28 ± 9.6; P = 0.486 |
| TAPSE, mm | 25 ± 4.0 | 12 ± 4.2; P < 0.0001 | 11 ± 2.8 | 14 ± 5.4; P = 0.037 |
| S′, cm/s | 15 ± 2.5 | 6.7 ± 2.3; P < 0.0001 | 6.3 ± 2.1 | 7.5 ± 2.7; P = 0.176 |
| RV 4-chamber LS, % | −22 ± 2.6 | −14 ± 3.2; P < 0.0001 | −13 ± 2.9 | −15 ± 3.4; P = 0.114 |
| RV free wall LS, % | −26 ± 3.8 | −15 ± 3.2; P < 0.0001 | −15 ± 2.8 | −16 ± 3.6; P = 0.165 |
| 3D EDVi, mL/m2 | 60 ± 12 | 121 ± 43; P < 0.0001 | 124 ± 30 | 115 ± 61; P = 0.345 |
| 3D ESVi, mL/m2 | 30 ± 7.2 | 80 ± 38; P < 0.0001 | 83 ± 27 | 75 ± 53; P = 0.161 |
| 3D EF, % | 60 ± 4 | 36 ± 8; P < 0.0001 | 34 ± 7 | 38 ± 9; P = 0.179 |
| Components of RV EF | ||||
| LEF, % | 25 ± 4.6 | 12 ± 5.0; P < 0.0001 | 10 ± 3.3 | 15 ± 5.7; P < 0.0001 |
| REF, % | 30 ± 6.4 | 14 ± 5.9; P < 0.0001 | 13 ± 4.9 | 16 ± 7.1; P = 0.075 |
| AEF, % | 29 ± 4.2 | 16 ± 4.7; P < 0.0001 | 17 ± 4.5 | 14 ± 4.7; P = 0.171 |
| LEFi | 0.42 ± 0.08 | 0.33 ± 0.10; P = 0.0002 | 0.29 ± 0.08 | 0.41 ± 0.11; P = 0.0008 |
| REFi | 0.51 ± 0.09 | 0.39 ± 0.11; P < 0.0001 | 0.38 ± 0.10 | 0.41 ± 0.11; P = 0.370 |
| AEFi | 0.48 ± 0.06 | 0.44 ± 0.10; P = 0.026 | 0.48 ± 0.09 | 0.36 ± 0.08; P = 0.0002 |
| Parameter . | Control group (N = 38) . | All SRV patients (N = 38) . | TGA post-atrial switch repair (N = 24) . | ccTGA (N = 14) . |
|---|---|---|---|---|
| Basal diameter, cm | 3.2 ± 0.4 | 5.5 ± 1.1; P < 0.0001 | 5.6 ± 1.0 | 5.3 ± 1.2; P = 0.432 |
| Mid diameter, cm | 2.2 ± 0.3 | 5.1 ± 9.8; P < 0.0001 | 4.8 ± 7.0 | 5.6 ± 1.2; P = 0.017 |
| Length, cm | 7.9 ± 0.6 | 7.9 ± 1.2; P = 0.803 | 8.1 ± 1.1 | 7.6 ± 1.3; P = 0.149 |
| EDAi, cm2/m2 | 14 ± 3.1 | 20 ± 5.1; P < 0.0001 | 21 ± 4.0 | 19 ± 6.4; P = 0.062 |
| ESAi, cm2/m2 | 9 ± 1.9 | 15 ± 5.0; P < 0.0001 | 15 ± 4.9 | 14 ± 5.3; P = 0.498 |
| FAC, % | 41 ± 4 | 27 ± 9; P < 0.0001 | 26 ± 8.8 | 28 ± 9.6; P = 0.486 |
| TAPSE, mm | 25 ± 4.0 | 12 ± 4.2; P < 0.0001 | 11 ± 2.8 | 14 ± 5.4; P = 0.037 |
| S′, cm/s | 15 ± 2.5 | 6.7 ± 2.3; P < 0.0001 | 6.3 ± 2.1 | 7.5 ± 2.7; P = 0.176 |
| RV 4-chamber LS, % | −22 ± 2.6 | −14 ± 3.2; P < 0.0001 | −13 ± 2.9 | −15 ± 3.4; P = 0.114 |
| RV free wall LS, % | −26 ± 3.8 | −15 ± 3.2; P < 0.0001 | −15 ± 2.8 | −16 ± 3.6; P = 0.165 |
| 3D EDVi, mL/m2 | 60 ± 12 | 121 ± 43; P < 0.0001 | 124 ± 30 | 115 ± 61; P = 0.345 |
| 3D ESVi, mL/m2 | 30 ± 7.2 | 80 ± 38; P < 0.0001 | 83 ± 27 | 75 ± 53; P = 0.161 |
| 3D EF, % | 60 ± 4 | 36 ± 8; P < 0.0001 | 34 ± 7 | 38 ± 9; P = 0.179 |
| Components of RV EF | ||||
| LEF, % | 25 ± 4.6 | 12 ± 5.0; P < 0.0001 | 10 ± 3.3 | 15 ± 5.7; P < 0.0001 |
| REF, % | 30 ± 6.4 | 14 ± 5.9; P < 0.0001 | 13 ± 4.9 | 16 ± 7.1; P = 0.075 |
| AEF, % | 29 ± 4.2 | 16 ± 4.7; P < 0.0001 | 17 ± 4.5 | 14 ± 4.7; P = 0.171 |
| LEFi | 0.42 ± 0.08 | 0.33 ± 0.10; P = 0.0002 | 0.29 ± 0.08 | 0.41 ± 0.11; P = 0.0008 |
| REFi | 0.51 ± 0.09 | 0.39 ± 0.11; P < 0.0001 | 0.38 ± 0.10 | 0.41 ± 0.11; P = 0.370 |
| AEFi | 0.48 ± 0.06 | 0.44 ± 0.10; P = 0.026 | 0.48 ± 0.09 | 0.36 ± 0.08; P = 0.0002 |
Data are presented as mean ± SD.
P (in All SRV) value indicates difference compared with the control group.
P (in ccTGA) value indicates difference compared with the TGA group.
EDAi, indexed end-diastolic area; EDVi, indexed end-diastolic volume; ESAi, indexed end-systolic area; ESVi, indexed end-systolic volume; LS, longitudinal strain.
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