Physical and respiratory functions between respiratory muscle weakness with and without frailty status
| . | Overall . | Non-frail . | Frail . | ||||
|---|---|---|---|---|---|---|---|
| . | . | RMW (−) . | RMW (+) . | P-value . | RMW (−) . | RMW (+) . | P-value . |
| . | (n = 1217) . | (n = 615) . | (n = 307) . | . | (n = 146) . | (n = 149) . | . |
| Gait speed, m/s | 1.08 (0.87–1.26) | 1.16 (1.00–1.32) | 1.05 (0.86–1.24) | <0.001 | 0.93 (0.73–1.11) | 0.80 (0.60–1.03) | 0.008 |
| Grip strength, kg | 24.6 (19.1–32.4) | 29.1 (21.7–35.1) | 24.3 (18.6–32.4) | <0.001 | 22.0 (17.0–26.1) | 20.0 (14.5–23.0) | <0.001 |
| SPPB, point | 12 (10–12) | 12 (12–12) | 12 (10–12) | <0.001 | 11 (8–12) | 10 (7–12) | 0.008 |
| 6MWD, m | 396 (289–477) | 437 (362–500) | 377 (277–458) | <0.001 | 326 (228–407) | 274 (161–380) | 0.008 |
| %FVC, % | 81 (67–93) | 87 (76–98) | 74 (58–87) | <0.001 | 82 (66–92) | 69 (57–82) | <0.001 |
| FEV1/FVC, % | 78 (72–82) | 79 (74–83) | 77 (70–82) | <0.001 | 75 (70–82) | 77 (70–83) | 0.307 |
| PImax, cmH2O | 53.5 (34.5–74.5) | 70.9 (56.0–88.8) | 31.8 (23.1–44.2) | <0.001 | 60.3 (45.6–72.7) | 26.2 (19.9–36.4) | <0.001 |
| %PImax, % | 81 (57–105) | 99 (84–121) | 53 (39–61) | <0.001 | 91 (82–105) | 47 (33–58) | <0.001 |
| . | Overall . | Non-frail . | Frail . | ||||
|---|---|---|---|---|---|---|---|
| . | . | RMW (−) . | RMW (+) . | P-value . | RMW (−) . | RMW (+) . | P-value . |
| . | (n = 1217) . | (n = 615) . | (n = 307) . | . | (n = 146) . | (n = 149) . | . |
| Gait speed, m/s | 1.08 (0.87–1.26) | 1.16 (1.00–1.32) | 1.05 (0.86–1.24) | <0.001 | 0.93 (0.73–1.11) | 0.80 (0.60–1.03) | 0.008 |
| Grip strength, kg | 24.6 (19.1–32.4) | 29.1 (21.7–35.1) | 24.3 (18.6–32.4) | <0.001 | 22.0 (17.0–26.1) | 20.0 (14.5–23.0) | <0.001 |
| SPPB, point | 12 (10–12) | 12 (12–12) | 12 (10–12) | <0.001 | 11 (8–12) | 10 (7–12) | 0.008 |
| 6MWD, m | 396 (289–477) | 437 (362–500) | 377 (277–458) | <0.001 | 326 (228–407) | 274 (161–380) | 0.008 |
| %FVC, % | 81 (67–93) | 87 (76–98) | 74 (58–87) | <0.001 | 82 (66–92) | 69 (57–82) | <0.001 |
| FEV1/FVC, % | 78 (72–82) | 79 (74–83) | 77 (70–82) | <0.001 | 75 (70–82) | 77 (70–83) | 0.307 |
| PImax, cmH2O | 53.5 (34.5–74.5) | 70.9 (56.0–88.8) | 31.8 (23.1–44.2) | <0.001 | 60.3 (45.6–72.7) | 26.2 (19.9–36.4) | <0.001 |
| %PImax, % | 81 (57–105) | 99 (84–121) | 53 (39–61) | <0.001 | 91 (82–105) | 47 (33–58) | <0.001 |
Values are median (interquartile range).
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PImax, maximal inspiratory pressure; RMW, respiratory muscle weakness; SPPB, short physical performance battery; 6MWD, 6-min walk distance.
Physical and respiratory functions between respiratory muscle weakness with and without frailty status
| . | Overall . | Non-frail . | Frail . | ||||
|---|---|---|---|---|---|---|---|
| . | . | RMW (−) . | RMW (+) . | P-value . | RMW (−) . | RMW (+) . | P-value . |
| . | (n = 1217) . | (n = 615) . | (n = 307) . | . | (n = 146) . | (n = 149) . | . |
| Gait speed, m/s | 1.08 (0.87–1.26) | 1.16 (1.00–1.32) | 1.05 (0.86–1.24) | <0.001 | 0.93 (0.73–1.11) | 0.80 (0.60–1.03) | 0.008 |
| Grip strength, kg | 24.6 (19.1–32.4) | 29.1 (21.7–35.1) | 24.3 (18.6–32.4) | <0.001 | 22.0 (17.0–26.1) | 20.0 (14.5–23.0) | <0.001 |
| SPPB, point | 12 (10–12) | 12 (12–12) | 12 (10–12) | <0.001 | 11 (8–12) | 10 (7–12) | 0.008 |
| 6MWD, m | 396 (289–477) | 437 (362–500) | 377 (277–458) | <0.001 | 326 (228–407) | 274 (161–380) | 0.008 |
| %FVC, % | 81 (67–93) | 87 (76–98) | 74 (58–87) | <0.001 | 82 (66–92) | 69 (57–82) | <0.001 |
| FEV1/FVC, % | 78 (72–82) | 79 (74–83) | 77 (70–82) | <0.001 | 75 (70–82) | 77 (70–83) | 0.307 |
| PImax, cmH2O | 53.5 (34.5–74.5) | 70.9 (56.0–88.8) | 31.8 (23.1–44.2) | <0.001 | 60.3 (45.6–72.7) | 26.2 (19.9–36.4) | <0.001 |
| %PImax, % | 81 (57–105) | 99 (84–121) | 53 (39–61) | <0.001 | 91 (82–105) | 47 (33–58) | <0.001 |
| . | Overall . | Non-frail . | Frail . | ||||
|---|---|---|---|---|---|---|---|
| . | . | RMW (−) . | RMW (+) . | P-value . | RMW (−) . | RMW (+) . | P-value . |
| . | (n = 1217) . | (n = 615) . | (n = 307) . | . | (n = 146) . | (n = 149) . | . |
| Gait speed, m/s | 1.08 (0.87–1.26) | 1.16 (1.00–1.32) | 1.05 (0.86–1.24) | <0.001 | 0.93 (0.73–1.11) | 0.80 (0.60–1.03) | 0.008 |
| Grip strength, kg | 24.6 (19.1–32.4) | 29.1 (21.7–35.1) | 24.3 (18.6–32.4) | <0.001 | 22.0 (17.0–26.1) | 20.0 (14.5–23.0) | <0.001 |
| SPPB, point | 12 (10–12) | 12 (12–12) | 12 (10–12) | <0.001 | 11 (8–12) | 10 (7–12) | 0.008 |
| 6MWD, m | 396 (289–477) | 437 (362–500) | 377 (277–458) | <0.001 | 326 (228–407) | 274 (161–380) | 0.008 |
| %FVC, % | 81 (67–93) | 87 (76–98) | 74 (58–87) | <0.001 | 82 (66–92) | 69 (57–82) | <0.001 |
| FEV1/FVC, % | 78 (72–82) | 79 (74–83) | 77 (70–82) | <0.001 | 75 (70–82) | 77 (70–83) | 0.307 |
| PImax, cmH2O | 53.5 (34.5–74.5) | 70.9 (56.0–88.8) | 31.8 (23.1–44.2) | <0.001 | 60.3 (45.6–72.7) | 26.2 (19.9–36.4) | <0.001 |
| %PImax, % | 81 (57–105) | 99 (84–121) | 53 (39–61) | <0.001 | 91 (82–105) | 47 (33–58) | <0.001 |
Values are median (interquartile range).
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PImax, maximal inspiratory pressure; RMW, respiratory muscle weakness; SPPB, short physical performance battery; 6MWD, 6-min walk distance.
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