Liver/peripheral blood (L/P) ratio data, and theoretical postmortem redistribution factor (Ft): alphabetical listing for 44 drugs.
| Drug . | n . | L/P (median) . | Ft . |
|---|---|---|---|
| Acetaminophen | 15 | 1.1 | 1.0 |
| Amiodarone | 5 | 41.9 | 3.6 |
| Amitriptyline | 57 | 16.4 | 2.3 |
| Amlodipine | 9 | 27.8 | 2.9 |
| Amphetamine | 15 | 7.0 | 1.6 |
| Bupropion | 11 | 1.0 | 1.0 |
| Carisoprodol | 11 | 2.0 | 1.1 |
| Chlorpheniramine | 3 | 9.5 | 1.8 |
| Citalopram | 37 | 7.5 | 1.7 |
| Clomipramine | 5 | 61.0 | 4.3 |
| Clozapine | 12 | 6.7 | 1.6 |
| Cyclobenzaprine | 13 | 19.6 | 2.5 |
| Desipramine | 6 | 44.6 | 3.7 |
| Dextromethorphan | 4 | 8.6 | 1.8 |
| Diltiazem | 8 | 17.2 | 2.4 |
| Diphenhydramine | 54 | 6.7 | 1.6 |
| Doxepin | 20 | 19.4 | 2.5 |
| Doxylamine | 3 | 2.9 | 1.2 |
| Fentanyl | 16 | 5.9 | 1.5 |
| Fluoxetine | 48 | 30.0 | 3.1 |
| Gabapentin | 28 | 0.65 | 0.97 |
| Guaifenesin | 5 | 0.9 | 1.0 |
| Hydrocodone | 38 | 3.0 | 1.2 |
| Hydroxyzine | 10 | 12.3 | 2.0 |
| Imipramine | 6 | 28.8 | 3.0 |
| Lamotrigine | 3 | 8.5 | 1.8 |
| Meprobamate | 8 | 0.9 | 1.0 |
| Methadone | 94 | 4.8 | 1.4 |
| Methamphetamine | 18 | 6.2 | 1.6 |
| Metoprolol | 6 | 3.5 | 1.3 |
| Mirtazapine | 5 | 12.0 | 2.0 |
| Naproxen | 20 | 1.0 | 1.0 |
| Olanzapine | 20 | 12.0 | 2.0 |
| Paroxetine | 19 | 29.2 | 3.0 |
| Promethazine | 9 | 9.1 | 1.8 |
| Propoxyphene | 35 | 9.0 | 1.8 |
| Propranolol | 6 | 10.9 | 1.9 |
| Quetiapine | 65 | 11.2 | 2.0 |
| Sertraline | 9 | 76.0 | 4.8 |
| Tramadol | 36 | 2.3 | 1.1 |
| Trazodone | 19 | 2.8 | 1.2 |
| Venlafaxine | 42 | 3.3 | 1.3 |
| Zolpidem | 14 | 2.4 | 1.2 |
| Ethanol | 1.0 |
| Drug . | n . | L/P (median) . | Ft . |
|---|---|---|---|
| Acetaminophen | 15 | 1.1 | 1.0 |
| Amiodarone | 5 | 41.9 | 3.6 |
| Amitriptyline | 57 | 16.4 | 2.3 |
| Amlodipine | 9 | 27.8 | 2.9 |
| Amphetamine | 15 | 7.0 | 1.6 |
| Bupropion | 11 | 1.0 | 1.0 |
| Carisoprodol | 11 | 2.0 | 1.1 |
| Chlorpheniramine | 3 | 9.5 | 1.8 |
| Citalopram | 37 | 7.5 | 1.7 |
| Clomipramine | 5 | 61.0 | 4.3 |
| Clozapine | 12 | 6.7 | 1.6 |
| Cyclobenzaprine | 13 | 19.6 | 2.5 |
| Desipramine | 6 | 44.6 | 3.7 |
| Dextromethorphan | 4 | 8.6 | 1.8 |
| Diltiazem | 8 | 17.2 | 2.4 |
| Diphenhydramine | 54 | 6.7 | 1.6 |
| Doxepin | 20 | 19.4 | 2.5 |
| Doxylamine | 3 | 2.9 | 1.2 |
| Fentanyl | 16 | 5.9 | 1.5 |
| Fluoxetine | 48 | 30.0 | 3.1 |
| Gabapentin | 28 | 0.65 | 0.97 |
| Guaifenesin | 5 | 0.9 | 1.0 |
| Hydrocodone | 38 | 3.0 | 1.2 |
| Hydroxyzine | 10 | 12.3 | 2.0 |
| Imipramine | 6 | 28.8 | 3.0 |
| Lamotrigine | 3 | 8.5 | 1.8 |
| Meprobamate | 8 | 0.9 | 1.0 |
| Methadone | 94 | 4.8 | 1.4 |
| Methamphetamine | 18 | 6.2 | 1.6 |
| Metoprolol | 6 | 3.5 | 1.3 |
| Mirtazapine | 5 | 12.0 | 2.0 |
| Naproxen | 20 | 1.0 | 1.0 |
| Olanzapine | 20 | 12.0 | 2.0 |
| Paroxetine | 19 | 29.2 | 3.0 |
| Promethazine | 9 | 9.1 | 1.8 |
| Propoxyphene | 35 | 9.0 | 1.8 |
| Propranolol | 6 | 10.9 | 1.9 |
| Quetiapine | 65 | 11.2 | 2.0 |
| Sertraline | 9 | 76.0 | 4.8 |
| Tramadol | 36 | 2.3 | 1.1 |
| Trazodone | 19 | 2.8 | 1.2 |
| Venlafaxine | 42 | 3.3 | 1.3 |
| Zolpidem | 14 | 2.4 | 1.2 |
| Ethanol | 1.0 |
Liver/peripheral blood (L/P) ratio data, and theoretical postmortem redistribution factor (Ft): alphabetical listing for 44 drugs.
| Drug . | n . | L/P (median) . | Ft . |
|---|---|---|---|
| Acetaminophen | 15 | 1.1 | 1.0 |
| Amiodarone | 5 | 41.9 | 3.6 |
| Amitriptyline | 57 | 16.4 | 2.3 |
| Amlodipine | 9 | 27.8 | 2.9 |
| Amphetamine | 15 | 7.0 | 1.6 |
| Bupropion | 11 | 1.0 | 1.0 |
| Carisoprodol | 11 | 2.0 | 1.1 |
| Chlorpheniramine | 3 | 9.5 | 1.8 |
| Citalopram | 37 | 7.5 | 1.7 |
| Clomipramine | 5 | 61.0 | 4.3 |
| Clozapine | 12 | 6.7 | 1.6 |
| Cyclobenzaprine | 13 | 19.6 | 2.5 |
| Desipramine | 6 | 44.6 | 3.7 |
| Dextromethorphan | 4 | 8.6 | 1.8 |
| Diltiazem | 8 | 17.2 | 2.4 |
| Diphenhydramine | 54 | 6.7 | 1.6 |
| Doxepin | 20 | 19.4 | 2.5 |
| Doxylamine | 3 | 2.9 | 1.2 |
| Fentanyl | 16 | 5.9 | 1.5 |
| Fluoxetine | 48 | 30.0 | 3.1 |
| Gabapentin | 28 | 0.65 | 0.97 |
| Guaifenesin | 5 | 0.9 | 1.0 |
| Hydrocodone | 38 | 3.0 | 1.2 |
| Hydroxyzine | 10 | 12.3 | 2.0 |
| Imipramine | 6 | 28.8 | 3.0 |
| Lamotrigine | 3 | 8.5 | 1.8 |
| Meprobamate | 8 | 0.9 | 1.0 |
| Methadone | 94 | 4.8 | 1.4 |
| Methamphetamine | 18 | 6.2 | 1.6 |
| Metoprolol | 6 | 3.5 | 1.3 |
| Mirtazapine | 5 | 12.0 | 2.0 |
| Naproxen | 20 | 1.0 | 1.0 |
| Olanzapine | 20 | 12.0 | 2.0 |
| Paroxetine | 19 | 29.2 | 3.0 |
| Promethazine | 9 | 9.1 | 1.8 |
| Propoxyphene | 35 | 9.0 | 1.8 |
| Propranolol | 6 | 10.9 | 1.9 |
| Quetiapine | 65 | 11.2 | 2.0 |
| Sertraline | 9 | 76.0 | 4.8 |
| Tramadol | 36 | 2.3 | 1.1 |
| Trazodone | 19 | 2.8 | 1.2 |
| Venlafaxine | 42 | 3.3 | 1.3 |
| Zolpidem | 14 | 2.4 | 1.2 |
| Ethanol | 1.0 |
| Drug . | n . | L/P (median) . | Ft . |
|---|---|---|---|
| Acetaminophen | 15 | 1.1 | 1.0 |
| Amiodarone | 5 | 41.9 | 3.6 |
| Amitriptyline | 57 | 16.4 | 2.3 |
| Amlodipine | 9 | 27.8 | 2.9 |
| Amphetamine | 15 | 7.0 | 1.6 |
| Bupropion | 11 | 1.0 | 1.0 |
| Carisoprodol | 11 | 2.0 | 1.1 |
| Chlorpheniramine | 3 | 9.5 | 1.8 |
| Citalopram | 37 | 7.5 | 1.7 |
| Clomipramine | 5 | 61.0 | 4.3 |
| Clozapine | 12 | 6.7 | 1.6 |
| Cyclobenzaprine | 13 | 19.6 | 2.5 |
| Desipramine | 6 | 44.6 | 3.7 |
| Dextromethorphan | 4 | 8.6 | 1.8 |
| Diltiazem | 8 | 17.2 | 2.4 |
| Diphenhydramine | 54 | 6.7 | 1.6 |
| Doxepin | 20 | 19.4 | 2.5 |
| Doxylamine | 3 | 2.9 | 1.2 |
| Fentanyl | 16 | 5.9 | 1.5 |
| Fluoxetine | 48 | 30.0 | 3.1 |
| Gabapentin | 28 | 0.65 | 0.97 |
| Guaifenesin | 5 | 0.9 | 1.0 |
| Hydrocodone | 38 | 3.0 | 1.2 |
| Hydroxyzine | 10 | 12.3 | 2.0 |
| Imipramine | 6 | 28.8 | 3.0 |
| Lamotrigine | 3 | 8.5 | 1.8 |
| Meprobamate | 8 | 0.9 | 1.0 |
| Methadone | 94 | 4.8 | 1.4 |
| Methamphetamine | 18 | 6.2 | 1.6 |
| Metoprolol | 6 | 3.5 | 1.3 |
| Mirtazapine | 5 | 12.0 | 2.0 |
| Naproxen | 20 | 1.0 | 1.0 |
| Olanzapine | 20 | 12.0 | 2.0 |
| Paroxetine | 19 | 29.2 | 3.0 |
| Promethazine | 9 | 9.1 | 1.8 |
| Propoxyphene | 35 | 9.0 | 1.8 |
| Propranolol | 6 | 10.9 | 1.9 |
| Quetiapine | 65 | 11.2 | 2.0 |
| Sertraline | 9 | 76.0 | 4.8 |
| Tramadol | 36 | 2.3 | 1.1 |
| Trazodone | 19 | 2.8 | 1.2 |
| Venlafaxine | 42 | 3.3 | 1.3 |
| Zolpidem | 14 | 2.4 | 1.2 |
| Ethanol | 1.0 |
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