| Clinical . | . | Resistance Mutation . | Sensitive Polymorphisms . | ||||
|---|---|---|---|---|---|---|---|
| History . | Nb . | UL97 . | UL54 . | UL56 . | UL97 . | UL54 . | UL56 . |
| Congenital HCMV | 6 | 0 | 0 | 0 | 0 | 5 | 0 |
| HIV | 2 | 0 | 0 | 0 | 1 | 2 | 0 |
| IBD | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| CVID | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Transplant Recipients | 83 | 21 | 5 | 1 | 4 | 58 | 4 |
| HSCT | 30 | 3 | 3 | 1 | 2 | 23 | 2 |
| SOT | 53 | 18 | 2 | 0 | 2 | 35 | 2 |
| Heart | 11 | 4 | 1 | 0 | 0 | 5 | 1 |
| Lung | 6 | 4 | 1 | 0 | 0 | 5 | 0 |
| Liver | 8 | 3 | 0 | 0 | 0 | 6 | 0 |
| Kidney | 25 | 7 | 0 | 0 | 2 | 17 | 1 |
| Liver-kidney | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Pancreas-kidney | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| Sample Type | |||||||
| Plasma | 84 | 20 | 4 | 1 | 5 | 58 | 4 |
| Whole blood | 4 | 1 | 1 | 0 | 0 | 4 | 0 |
| GI biopsy | 5 | 0 | 0 | 0 | 0 | 4 | 0 |
| Aqueous humour | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Total | 94 | 21 | 5 | 1 | 5 | 67 | 4 |
| Clinical . | . | Resistance Mutation . | Sensitive Polymorphisms . | ||||
|---|---|---|---|---|---|---|---|
| History . | Nb . | UL97 . | UL54 . | UL56 . | UL97 . | UL54 . | UL56 . |
| Congenital HCMV | 6 | 0 | 0 | 0 | 0 | 5 | 0 |
| HIV | 2 | 0 | 0 | 0 | 1 | 2 | 0 |
| IBD | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| CVID | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Transplant Recipients | 83 | 21 | 5 | 1 | 4 | 58 | 4 |
| HSCT | 30 | 3 | 3 | 1 | 2 | 23 | 2 |
| SOT | 53 | 18 | 2 | 0 | 2 | 35 | 2 |
| Heart | 11 | 4 | 1 | 0 | 0 | 5 | 1 |
| Lung | 6 | 4 | 1 | 0 | 0 | 5 | 0 |
| Liver | 8 | 3 | 0 | 0 | 0 | 6 | 0 |
| Kidney | 25 | 7 | 0 | 0 | 2 | 17 | 1 |
| Liver-kidney | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Pancreas-kidney | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| Sample Type | |||||||
| Plasma | 84 | 20 | 4 | 1 | 5 | 58 | 4 |
| Whole blood | 4 | 1 | 1 | 0 | 0 | 4 | 0 |
| GI biopsy | 5 | 0 | 0 | 0 | 0 | 4 | 0 |
| Aqueous humour | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Total | 94 | 21 | 5 | 1 | 5 | 67 | 4 |
Abbreviations: CVID, common variable immunodeficiency; GI, gastrointestinal; HCMV, human cytomegalovirus; HIV, human immunodeficiency virus; HSCT, hematopoietic stem cell transplant; IBD, inflammatory bowel disease; SNP, single-nucleotide polymorphism; SOT, solid organ transplant.
Number of subjects with resistance mutations and sensitive polymorphisms in the antiviral target genes are indicated according to the clinical history and the type of sample.
The number of subjects.
| Clinical . | . | Resistance Mutation . | Sensitive Polymorphisms . | ||||
|---|---|---|---|---|---|---|---|
| History . | Nb . | UL97 . | UL54 . | UL56 . | UL97 . | UL54 . | UL56 . |
| Congenital HCMV | 6 | 0 | 0 | 0 | 0 | 5 | 0 |
| HIV | 2 | 0 | 0 | 0 | 1 | 2 | 0 |
| IBD | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| CVID | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Transplant Recipients | 83 | 21 | 5 | 1 | 4 | 58 | 4 |
| HSCT | 30 | 3 | 3 | 1 | 2 | 23 | 2 |
| SOT | 53 | 18 | 2 | 0 | 2 | 35 | 2 |
| Heart | 11 | 4 | 1 | 0 | 0 | 5 | 1 |
| Lung | 6 | 4 | 1 | 0 | 0 | 5 | 0 |
| Liver | 8 | 3 | 0 | 0 | 0 | 6 | 0 |
| Kidney | 25 | 7 | 0 | 0 | 2 | 17 | 1 |
| Liver-kidney | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Pancreas-kidney | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| Sample Type | |||||||
| Plasma | 84 | 20 | 4 | 1 | 5 | 58 | 4 |
| Whole blood | 4 | 1 | 1 | 0 | 0 | 4 | 0 |
| GI biopsy | 5 | 0 | 0 | 0 | 0 | 4 | 0 |
| Aqueous humour | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Total | 94 | 21 | 5 | 1 | 5 | 67 | 4 |
| Clinical . | . | Resistance Mutation . | Sensitive Polymorphisms . | ||||
|---|---|---|---|---|---|---|---|
| History . | Nb . | UL97 . | UL54 . | UL56 . | UL97 . | UL54 . | UL56 . |
| Congenital HCMV | 6 | 0 | 0 | 0 | 0 | 5 | 0 |
| HIV | 2 | 0 | 0 | 0 | 1 | 2 | 0 |
| IBD | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| CVID | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Transplant Recipients | 83 | 21 | 5 | 1 | 4 | 58 | 4 |
| HSCT | 30 | 3 | 3 | 1 | 2 | 23 | 2 |
| SOT | 53 | 18 | 2 | 0 | 2 | 35 | 2 |
| Heart | 11 | 4 | 1 | 0 | 0 | 5 | 1 |
| Lung | 6 | 4 | 1 | 0 | 0 | 5 | 0 |
| Liver | 8 | 3 | 0 | 0 | 0 | 6 | 0 |
| Kidney | 25 | 7 | 0 | 0 | 2 | 17 | 1 |
| Liver-kidney | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Pancreas-kidney | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| Sample Type | |||||||
| Plasma | 84 | 20 | 4 | 1 | 5 | 58 | 4 |
| Whole blood | 4 | 1 | 1 | 0 | 0 | 4 | 0 |
| GI biopsy | 5 | 0 | 0 | 0 | 0 | 4 | 0 |
| Aqueous humour | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Total | 94 | 21 | 5 | 1 | 5 | 67 | 4 |
Abbreviations: CVID, common variable immunodeficiency; GI, gastrointestinal; HCMV, human cytomegalovirus; HIV, human immunodeficiency virus; HSCT, hematopoietic stem cell transplant; IBD, inflammatory bowel disease; SNP, single-nucleotide polymorphism; SOT, solid organ transplant.
Number of subjects with resistance mutations and sensitive polymorphisms in the antiviral target genes are indicated according to the clinical history and the type of sample.
The number of subjects.
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