Table 2

Cox proportional hazard regressions: hazard ratio for all-cause death in cardiac resynchronization therapy with pacemaker vs. cardiac resynchronization therapy with defibrillator

AnalysisHazard ratio (95% CI)P-value
Unadjusted1.63 (1.38–1.92)<0.001
Age-adjusteda,b1.13 (0.95–1.35)0.165
Age and comorbidity adjustedc0.99 (0.81–1.20)0.89
Sensitivity analysis
Age and comorbidity adjusted + ambiguous NYHA patientsc1.04 (0.86–1.27)0.67
PSM approach
Age and comorbidity adjustedd1.16 (0.93–1.44)0.195
AnalysisHazard ratio (95% CI)P-value
Unadjusted1.63 (1.38–1.92)<0.001
Age-adjusteda,b1.13 (0.95–1.35)0.165
Age and comorbidity adjustedc0.99 (0.81–1.20)0.89
Sensitivity analysis
Age and comorbidity adjusted + ambiguous NYHA patientsc1.04 (0.86–1.27)0.67
PSM approach
Age and comorbidity adjustedd1.16 (0.93–1.44)0.195

CI, confidence interval; CRT-P; cardiac resynchronization therapy with pacemaker; CRT-D; cardiac resynchronization therapy with defibrillator; NYHA; New York Heart Association; PSM, propensity score matching.

a

Bivariate Cox regression.

b

Hazard ratio for increasing age (per year) 1.06 (95% CI: 1.05–1.07), P < 0.001.

c

Univariate Cox regression using weights from entropy balancing.

d

Univariate Cox regression using the propensity score matched sample.

Table 2

Cox proportional hazard regressions: hazard ratio for all-cause death in cardiac resynchronization therapy with pacemaker vs. cardiac resynchronization therapy with defibrillator

AnalysisHazard ratio (95% CI)P-value
Unadjusted1.63 (1.38–1.92)<0.001
Age-adjusteda,b1.13 (0.95–1.35)0.165
Age and comorbidity adjustedc0.99 (0.81–1.20)0.89
Sensitivity analysis
Age and comorbidity adjusted + ambiguous NYHA patientsc1.04 (0.86–1.27)0.67
PSM approach
Age and comorbidity adjustedd1.16 (0.93–1.44)0.195
AnalysisHazard ratio (95% CI)P-value
Unadjusted1.63 (1.38–1.92)<0.001
Age-adjusteda,b1.13 (0.95–1.35)0.165
Age and comorbidity adjustedc0.99 (0.81–1.20)0.89
Sensitivity analysis
Age and comorbidity adjusted + ambiguous NYHA patientsc1.04 (0.86–1.27)0.67
PSM approach
Age and comorbidity adjustedd1.16 (0.93–1.44)0.195

CI, confidence interval; CRT-P; cardiac resynchronization therapy with pacemaker; CRT-D; cardiac resynchronization therapy with defibrillator; NYHA; New York Heart Association; PSM, propensity score matching.

a

Bivariate Cox regression.

b

Hazard ratio for increasing age (per year) 1.06 (95% CI: 1.05–1.07), P < 0.001.

c

Univariate Cox regression using weights from entropy balancing.

d

Univariate Cox regression using the propensity score matched sample.

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